Results 101 to 110 of about 296,412 (302)

Digital transformation in Næstved Municipality: Digitalisation principles - friend or foe?

open access: yes, 2023
The purpose of this project is to examine the approach to digitalisation in a Danish municipality called Næstved. The municipality has chosen not to have a digital strategy and instead use digitalisation principles, which is why this project examines ...
Kristensen, William Dyrnesli   +2 more
core  

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

The Goldilocks Conundrum: The ‘Just Right’ Conditions for Design to Achieve Impact in Public and Third Sector Projects

open access: yes, 2016
What are the most important conditions necessary for a design-led approach to innovation or transformation to flourish in an organization? This paper introduces and discusses three ‘just right’ conditions for design to achieve the desired impact in the ...
White, Hazel, Yee, Joyce
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

ULOGA PREDUZETNIŠTVA I SPORTSKOG MENADŽMENTA U RAZVOJU KLUPSKOG PROFESIONALNOG SPORTA [PDF]

open access: yesSport Mont, 2005
Development of professional sport experienced the important transformation in the last fifty years. The key factors of transformation were involvement of entrepreneur, business people and individual investitures in sport.
Ljubivoje Mladenović
doaj  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

Image Quick Search Based on F-shift Transformation

open access: yes, 2020
Searching a given image belongs to which part of an image is a practical significance topic in computer vision, image and video processing. Commonly the images are compressed for efficient storage and transfer, while if we want to search a given image ...
Wang, J   +5 more
core   +1 more source

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