Results 91 to 100 of about 296,412 (302)

Measuring social-ecological resilience reveals opportunities for transforming environmental governance

Ecology and Society, 2019
Understanding the resilience of social-ecological systems can advance our ability to transform environmental governance and achieve ecologically sustainable and socially just outcomes. However, measuring this multidimensional emergent system property has
Anne K. Salomon, Allyson E. Quinlan, Gabrielle H. Pang, Daniel K. Okamoto, Leonardo Vazquez-Vera   +4 more
doaj   +1 more source

The end of the beginning: Understanding benefits realisation in transformation projects in the UK government

, 2020
This paper addresses the challenges in realising benefits from government transformation projects. No consensus has emerged on how organisational transformation from an information systems project can be efficiently achieved. By clarifying the context of
Cha, J., Winch, G.
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The Chinese Meaning of Just War and Its Impact on the Foreign Policy of the People’s Republic of China [PDF]

The image of China’s peaceful rise, which the Chinese government is keen to enforce in the world, stands in contrast to the view of China’s ascent as a threat.
Nadine Godehardt
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Safe and just operating spaces for regional social-ecological systems [PDF]

, 2014
Humanity faces a major global challenge in achieving wellbeing for all, while simultaneously ensuring that the biophysical processes and ecosystem services that underpin wellbeing are exploited within scientifically informed boundaries of sustainability.
Zhang, Ke, Cole, Megan, Dawson, Terence, Dawson, Terence P.; id_orcid, Carstensen, Jacob, Mackay, Anson W., Cornell, Sarah E., Lenton, Timothy M., Hossain, MS, Cole, MJ, Haberl, Helmut, Dearing, John A., Aponte Quiñones, Heyde Alexandra, Brown, S, Nykvist, Björn, Nykvist, B, Cornell, SE, Haberl, H, Eigenbrod, Felix, Hossain, Md.Sarwar, Lenton, Timothy, Jeffers, E, Lenton, TM, Poppy, Guy M., Carstensen, J, Raworth, Kate, Floerke, M, Poppy, GM, Jeffers, Elizabeth, Dyke, James G., Langdon, PG, Raworth, K, Wang, R, Hossain, Md Sarwar, Dyke, JG, Dawson, TP, Doncaster, C. Patrick, Dawson, Terence P., Langdon, Peter G., Hossain, Md. Sarwar, Flöerke, Martina, Wang, Rong, Mackay, AW, Dearing, JA, Doncaster, CP, Mackay, Anson, Eigenbrod, F, Cole, Megan J., Brown, Sally, Flörke, Martina, Cornell, Sarah, Zhang, K   +51 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Understanding the dynamics of urban just transitions: An interdisciplinary analysis with latent dirichlet allocation (LDA)

Journal of Urban Management
Despite the presence of literature on just transitions in cities, the knowledge gap exists in analyzing the evolving trends and trajectories of justice themes in urban transitions.
Yuhang Sun, Ye Luo, Xuepeng Qian, Liang Dong   +3 more
doaj   +1 more source

Land use and human impact in the Dinaric karst. [PDF]

International Journal of Speleology, 1999
The artice presents Dinaric karst, human impacts in the area, and its long history of deforestation, transformation into stony semi-desert, and a century long reforestation, where plans to restore the primary thick soil were just hoping against hope.
Gams Ivan, Gabrovec Matej
doaj