Results 81 to 90 of about 296,412 (302)

An exploratory study of organisational transformation in manufacturing SMEs

open access: yes, 2010
In a competitive environment organisations are driven to continuously change and adapt to emerging conditions in order to sustain competitive advantage. The reported decline of the manufacturing sector in the UK is believed to be the result, in part, of ...
Mendibil, Kepa   +2 more
core  

The Transformation of Haus der Statistik: The three-dimensional City

open access: yes, 2022
This Master Thesis outlines the Transformation of Haus der Statistik a 6905,6m2 complex building located in Berlin Mitte near Alexanderplatz. The main motivation behind developing this Thesis was to form a proposal based on the given competition material,
Helleberg, Catrine Neddergaard   +2 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

How Democratic Is Just Enough? Critical Reflections on the Transformative Potential of the Berlin Food Policy Council

open access: yesUrban Planning
In recent years, global social movements have increasingly challenged the corporate food regime, advocating for socio‐ecological transformations in the agri‐food system. This article questions whether food activists’ discourse and actions may potentially
Lea Loretta Zentgraf
doaj   +1 more source

Strategic polymorphism requires just two combinators! [PDF]

open access: yes, 2003
In previous work, we introduced the notion of functional strategies: first-class generic functions that can traverse terms of any type while mixing uniform and type-specific behaviour.
Visser, Joost   +3 more
core  

The psychological dimension of transformation in teacher learning [PDF]

open access: yes, 2012
Against a background which recognises pedagogical content knowledge as the distinctive element of teacher competence/expertise, this theoretical essay argues for its central construct - that of transformation – to be understood by teachers and teacher ...
MacLellan, Effie, Effie Maclellan
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Etude on Recursion Elimination

open access: yesМоделирование и анализ информационных систем, 2018
Transformation-based program verification was a very important topic in early years of theory of programming. Great computer scientists contributed to these studies: John McCarthy, Amir Pnueli, Donald Knuth ... Many fascinating examples were examined and
Nikolay Shilov
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

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