Results 51 to 60 of about 296,412 (302)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Transforming a traditional manufacturing system into a JUST-INJIME system with KANBAN [PDF]

open access: yes1988 Winter Simulation Conference Proceedings, 1988
Traditional Manufacturing systems, characterized by many U.S. fi rms, are known for maintaining relatively high levels of raw material, work-in-process, and finished goods inventories as a hedge against uncertainty in supplier delivery and quality, production rates and quality, and customer demand.
Harold Dyck   +2 more
openaire   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Living Transformation: The Alchemy of Change in an Epochal Shift

open access: yes, 2023
Just as quantum scientists experienced an existential disorientation, so must we, to understand how their findings upend what we think we know about transformative learning.
Lange, EA
core   +1 more source

Coordinating Innovation in Digital Infrastructure: The Case of Transforming Offshore Project Delivery [PDF]

open access: yes, 2020
The relationship between digitalization, digital innovation, and digital transformation is an emerging topic in information systems (IS) research. Whereas IS researchers widely acknowledge that digitalization underpins both digital innovation and digital
Østerlie, Thomas   +3 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Seafarers in shipping’s decarbonization: role transformation, protection deficits, and just transition pathways

open access: yesFrontiers in Marine Science
The shipping industry is undergoing a critical phase of green transition, in which seafarers constitute the core driving force of decarbonization.
Juntao Gao, Jing Zhou
doaj   +1 more source

Application of the Elzaki iterative method to fractional partial differential equations

open access: yesBoundary Value Problems, 2023
In this article, we present an iterative transformation method for solving fractional partial differential equations that combines the Elzaki transform and iterative methods.
Yong He, Wei Zhang
doaj   +1 more source

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