Results 51 to 60 of about 2,294,108 (294)

Paradigm-Based Evaluation for Eco-Just Systems Transformation

Journal of MultiDisciplinary Evaluation, 2023
Social and ecological systems shape the extent to which humans and the rest of nature live together in a state of well-being. In this article, we work with two intertwined paradigms (i.e., worldviews) that underlie our social and ecological systems.
Beverly Parsons, Katherine Winters
openaire   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Application of the Elzaki iterative method to fractional partial differential equations

Boundary Value Problems, 2023
In this article, we present an iterative transformation method for solving fractional partial differential equations that combines the Elzaki transform and iterative methods.
Yong He, Wei Zhang
doaj   +1 more source

Transverse and longitudinal vibrations in amorphous silicon

, 2015
We show that harmonic vibrations in amorphous silicon can be decomposed to transverse and longitudinal components in all frequency range even in the absence of the well defined wave vector ${\bf q}$. For this purpose we define the transverse component of
Beltukov, Y. M., Fusco, C., Parshin, D. A., Tanguy, A.   +3 more
core   +3 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Seafarers in shipping’s decarbonization: role transformation, protection deficits, and just transition pathways

Frontiers in Marine Science
The shipping industry is undergoing a critical phase of green transition, in which seafarers constitute the core driving force of decarbonization.
Juntao Gao, Jing Zhou
doaj   +1 more source

Knowledge mapping of resilience and human rights in supply chains: A roadmapping taxonomy for twin green and digital transition design

Frontiers in Environmental Science, 2023
Supply chain sustainability (SCS) has gone beyond the sustainability-performance approach, towards the increasing adoption of the sustainability-practice approach.
Chung-Lien Pan, Chung-Lien Pan, Chung-Lien Pan, Chung-Lien Pan, Han-Teng Liao, Han-Teng Liao, Han-Teng Liao, Yuan Zhang, Yuan Zhang   +8 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Digital mental health care: five lessons from Act 1 and a preview of Acts 2–5

npj Digital Medicine, 2023
Digital tools are transforming mental health care. The promise of this transformation to improve outcomes has not yet been realized fully. While some have become skeptical, this article argues that we are just at the end of Act 1, with several ...
Thomas Insel
doaj   +1 more source

Nachhaltige Arbeit in Europa: Sozialökologische Transformation von Arbeit und Impulse aus der Pandemie

Momentum Quarterly, 2023
In der Coronapandemie haben der Staat und seine Institutionen eine enorme Handlungsfähigkeit bewiesen. Binnen weniger Tage und unter Verkürzung üblicher Konsultations- und Abstimmungsverfahren wurden die Folgen der Krise für die Gesundheit der Bürger ...
Sebastian Brandl, Ingo Matuschek
doaj   +1 more source