Results 71 to 80 of about 3,985,783 (290)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
LawsWith the expression “Just transition”, the European Commission refers to a new development model to bring in the environmental and digital transition “leaving no one behind”.
Sara Pugliese
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
A just transition for cellular dairy?
Canadian Food StudiesFood systems globally are under growing pressure to transition in response to climate change, ecological degradation, shifting consumer expectations, and persistent social inequities.
Evan Bowness +3 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Just Energy Transition Partnerships (JETPs) are political agreements between a group of donor countries and an emerging economy partner country to mobilise and coordinate public and private finance to support a just energy transition.
Selvaraju, Sangeeth +3 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Mapping the scale and scope of just transition finance in private credit and equity funds
This report develops a framework to map the scale and scope of the just transition for private equity and credit funds that have specialist expertise in sustainable and socially responsible investing. It provides evidence to inform the case for continued
Chanda, Arka, Tyson, Judith
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Abstract This chapter provides an overview of the history of transitional justice in postwar Germany. It argues that history questions certain key assumptions common in the literature on transitional justice, referencing the notion of transitional justice operating effectively as a form of historical and political pedagogy.
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