Results 111 to 120 of about 2,077,233 (302)
The Forgotten 150th: Why the Civil War Sesquicentennial is Far From Over
, 2016 Last spring, my friends told me that it was the perfect time to get into Civil War reenacting. “The 150th is over,” they said, “No one is going to care about the Civil War anymore, so everyone will be selling all their stuff.” Somehow, this bit of ...
Lauck, Jeffrey L.
core
Leonard Brooks—War Artist (1911–2011) [PDF]
, 2012 Just 13 days after his 100th birthday, Leonard Brooks, a Second World War Canadian artist passed away. Trained as a commercial artist, Brooks joined the Royal Canadian Navy (RCN) in 1943 and was appointed an official war artist the following year.
Brandon, Laura
core +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Brussels blog round up for 6 October – 12 October: Merkel inGreece, the Catalonia debate rages on, and EU wins the NobelPeace Prize. [PDF]
, 2012 Reaction to the EU’s 2012 Nobel Peace Prize award has been mixed. Open Europe draws a comparison with the “once celebrated actor who just got a lif etime achievement award”, arguing that while European integration did play a signif icant role in ensuring
Brown, Stuart A., Gilson, Chris
core
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
A Just War No Longer Exists: The Teaching and Trial of Don Lorenzo Milani [PDF]
, 1988 Reviewed Book: Milano, Lorenzo. A Just War No Longer Exists: The Teaching and Trial of Don Lorenzo Milani.
Kelly, Robert A.
core +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source