Results 91 to 100 of about 1,185,148 (303)
The Russo-Ukrainian conflict and the ethics of war of Augustine and Aquinas
Ethic@: an International Journal for Moral PhilosophyThis article analyzes the justice of the Russo-Ukrainian War from the views of just war theorists Augustine and Aquinas. Augustine of Hippo, in his war ethics, believed that war is both a consequence of sin and a potential remedy.
Pedro Erik Carneiro
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Who Fought Just War? Walzer’s Theory and the War in the Former Yugoslavia
Međunarodne Studije, 2015 Applying Walzer’s theory, this article analyzes the morality of the war in the former Yugoslavia. The main findings are the following: Serbia fought an unjust war during the entire 1991-99 period.
Miljenko Antić
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Warfighting for cyber deterrence: a strategic and moral imperative [PDF]
, 2017 Theories of cyber deterrence are developing rapidly. However, the literature is missing an important ingredient—warfighting for deterrence. This controversial idea, most commonly associated with nuclear strategy during the later stages of the Cold War ...
Lonsdale, David J.
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Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Jus in bello a operace Irácká svoboda
Obrana a Strategie, 2010 War is a constant feature of human affairs and a permanent topic of ethical debates. Moral reasoning about war and peace known as just war theory has its roots in Christian ethics and is connected to positive international law.
Eva DUŘPEKTOVÁ, Zdeněk KŘÍŽ
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Killer Drones, Legal Ethics, and the Inconvenient Referent
Lateral, 2018 I offer a close reading of the legal and political discourses by means of which the United States government recently has sought to legitimate its use of weaponized drones to carry out targeted assassinations of suspected anti-U.S.
Vaheed Ramazani
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Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan +6 more
wiley +1 more source