Results 121 to 130 of about 1,189,304 (300)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

The Concepts of War and Peace in Christian Philosophy

open access: yesReligions
This article examines the concepts of war and peace through the lens of Christian philosophy, integrating anthropological, ethical, and socio-political perspectives. It argues that while conflict is rooted in human biology and social organization, war is
Géza Kuminetz
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Book review: the philosophy of war and exile by Nolen Gertz [PDF]

open access: yes, 2015
Through a close critique of PTSD theory, just war theory, and Western ethics, combined with an empirical study of contemporary military training and torture methods, The Philosophy of War and Exile by Nolen Gertz is a compelling resource, writes Esther ...
Adaire, Esther
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Conceptions of War in Islamic Legal Theory and Practice [PDF]

open access: yes, 2007
The term Jihad, meaning Muslim ‘holy war,’ is a powerful symbol in contemporary society, signifying not only radical violence but the clash of Islamic and Western societies.
Pettygrove, Margaret
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

The Mozi and Just War Theory in Pre-Han Thought [PDF]

open access: yes, 2014
主題: 墨家思想研究的國際視野Conference Theme: International Perspectives in the Research of the Mohist ThoughtChina’s Warring States era (481–221 BCE) was marked by cruel, destructive, recurring warfare between the seven major warring states and numerous minor states.
Fraser, CJ
core  

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