Results 41 to 50 of about 1,352,476 (294)

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Review of Stutterer Interrupted: the Comedian Who Almost Didn't Happen by Nina G.

Disability Studies Quarterly, 2020
No abstract available.
Jennifer Justice
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Status of the Criminal Justice Information Sharing System; Legislative report

, 2009
Annual; Began with Jan. 1, 2009.; Description based on: Jan. 1, 2009; title from cover.; Mandated by Public Act 08-01, section 40 (h), an Act Concerning Criminal Justice Reform.; Imprint from letter of transmittal.; Latest issue consulted: Jan. 1, 2009.;
Connecticut. Criminal Justice Information System Governing Board.
core   +1 more source

Mobile health interventions for HIV/STI prevention among youth in low- and middle-income countries (LMICs): a systematic review of studies reporting implementation outcomes

Implementation Science Communications, 2021
Background Advances and proliferation of technologies such as mobile phones may provide opportunities to improve access to HIV/STI services and reach young people with high risk for HIV and STI.
Ucheoma Nwaozuru, Chisom Obiezu-Umeh, Thembekile Shato, Florida Uzoaru, Stacey Mason, Victoria Carter, Sunita Manu, Karan Modi, Jessica Parker, Oliver Ezechi, Juliet Iwelunmor   +10 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Comparing social stigma of anorexia nervosa, bulimia nervosa, and binge-eating disorder: A quantitative experimental study

Journal of Eating Disorders
Background Currently, we know little regarding how stigma attributed to eating disorders compares to that of other psychological disorders and additionally within different types of eating disorders.
Carlye S. Aird, Bennett A. A. Reisinger, Stephanie N. Webb, David H. Gleaves   +3 more
doaj   +1 more source

Ensuring the competitiveness of innovation projects through the management of their life cycle parameters [PDF]

E3S Web of Conferences, 2019
The purpose of this paper is to develop guidelines for the assessment and implementation of innovation projects, which ensure its competitiveness through the management of life cycle parameters.
Minaeva Elena, Yutkina Olga, Anoshina Yuliya, Maslyukova Ekaterina, Karapetyan Irina   +4 more
doaj   +1 more source