Results 71 to 80 of about 222,060 (267)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The development of public health policy in the context of the transformation of socio-economic systems

RUDN Journal of Public Administration
The study examines the mechanisms of implementation of state policy in the field of healthcare and analyzes the level of implementation of the State Program “Development of healthcare in Moscow (Metropolitan Healthcare)”, which allows us to assess their ...
Margarita V. Alexandrova, Ekaterina A. Maslyukova, Olga V. Yutkina   +2 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Widening the aperture of the opportunity lens: engaging local stakeholders in the interpretation of crime concentrations

Crime Science
This article discusses the value of integrating spatial crime analysis with local stakeholder engagement to fully leverage opportunity theory in community crime prevention.
Nancy La Vigne, Alejandro Giménez-Santana, Gaspard Tissandier, Adriana Santos   +3 more
doaj   +1 more source

Taxation in insolvency (bankruptcy) procedures of legal entities

Правоприменение
Subject. The article analyzes a set of norms related to the legal regulation of personal income tax, corporate income tax, VAT, and other taxes, as well as the order of their collection (payment) from a bankrupt, depending on its organizational and legal
I. A. Tsindeliani, T. D. Sadovskaya, E. G. Vasilyeva, Zh. G. Popkova   +3 more
doaj   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Managing environmental sanitation in the catchment area of Benya Lagoon, Ghana: Education, regulation or infrastructure management as a matter of strategic priority?

Cogent Social Sciences, 2019
Poor environmental sanitation is a menace in many parts of the world, but particularly so in the developing countries, including Ghana. While several strategies may be available for managing this environmental menace, interventions in education ...
Justice Mensah
doaj   +1 more source

Ethnographies of Justice: Doing Some Justice to “Justice and Law”

PoLAR: Political and Legal Anthropology Review, 2020
AbstractThis symposium seeks to generate fresh theoretical thinking about the relations between justice and law. In particular, it aims to reappraise justice conceptually by insisting on a theoretical openness to justice within and beyond law, and indeed against law.
openaire   +1 more source