Results 191 to 200 of about 304,067 (315)

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Genres of Inquiry in Design-Science Research: Justification and Evaluation of Knowledge Production

, 2015
Recognizing that design is at the core of information systems development has led to a design-science research paradigm where differing kinds of knowledge goals give form to differing kinds of knowledge processes within a single study.
Kaul, M., Kaul, Mala, Storey, Veda C., Storey, V., Baskerville, Richard L, Baskerville, Richard   +5 more
core  

The FDA's adoption of Bayesian methodology: transforming clinical trial justification from biosimilars to broader drug development. [PDF]

Front Med (Lausanne)
Niazi SK.
europepmc   +1 more source

Physical Origin of Temperature Induced Activation Energy Switching in Electrically Conductive Cement

Advanced Science, EarlyView.
The temperature‐induced Arrhenius activation energy switching phenomenon of electrical conduction in electrically conductive cement originates from structural degradation within the biphasic ionic‐electronic conduction architecture and shows percolation‐governed characteristics: pore network opening dominates the low‐percolation regime with downward ...
Jiacheng Zhang, Xinyuan Ke, Andrew Heath, Richard J. Ball, Jiawei Xie, Jinchen Fan, Guisheng Li, Kevin Paine   +7 more
wiley   +1 more source

Justification of Imaging Referrals: A Cross-Sectional Survey of Referring Physicians' Knowledge, Practices, and Barriers. [PDF]

AJPM Focus
Abuzaid M, Almuqbil N, Hamd ZY.
europepmc   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

Advanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey, Sudhir Kumar Rai, Li Ma, Lauren Higa, Vedbar Khadka, Hua Yang, Youping Deng   +6 more
wiley   +1 more source

HR regulation and legal justification (Unit 1-2) : presentation course HUMAN RIGHTS

Tuliakov V. O. HR regulation and legal justification (Unit 1-2) : presentation course HUMAN RIGHTS / V. O. Tuliakov. - Odesa, 2025. - 18 p.
Туляков, Вячеслав Олексійович, Tuliakov, Viacheslav O., Туляков, В. О.   +2 more
core  

Idiopathic granulomatous mastitis: A scoping review to determine the quality and geography of the evidence base. [PDF]

Breast
Ahari D, Argus L, Castelhano R, Shah S, Johri G, MacInnes E, Darlow C, Lyburn I, Sharma N, Sharma V, Shukla R, Bradley R, Arafin N, Kirwan CC.   +13 more
europepmc   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

A Technical Framework for Predicting Regulatory Deficiencies in Pharmaceutical Chemistry, Manufacturing, and Controls (CMC) Submissions Using Machine Learning. [PDF]

Cureus
Modi P.
europepmc   +1 more source