Comorbidities and clinical outcomes in adult- and juvenile-onset Huntington's disease: a study of linked Swedish National Registries (2002-2019). [PDF]
J Neurol, 2023 Furby H +7 more
europepmc +1 more source
Delayed Onset and Reduced Cognitive Deficits through Pre-Conditioning with 3-Nitropropionic Acid is Dependent on Sex and CAG Repeat Length in the R6/2 Mouse Model of Huntington's Disease. [PDF]
, 2016 BACKGROUND: Impairments in energy metabolism are implicated in Huntington's disease (HD) pathogenesis. Reduced levels of the mitochondrial enzyme succinate dehydrogenase (SDH), the main element of complex II, are observed post mortem in the brains of HD ...
Morton, A Jennifer +1 more
core
Prey Remains From Stomachs of Killer Whales ( Orcinus orca ) Stranded in Alaska, 2005–2021
Marine Mammal Science, Volume 41, Issue 4, October 2025.
Anna L. Bryan +6 more
wiley +1 more source
Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage [PDF]
, 2017 To test the hypotheses that mutant huntingtin protein length and wild-type huntingtin dosage have important effects on disease-related transcriptional dysfunction, we compared the changes in mRNA in seven genetic mouse models of Huntington's disease (HD)
Albin, Roger +23 more
core
Huntington disease: natural history, biomarkers and prospects for therapeutics [PDF]
, 2014 Huntington disease (HD) can be seen as a model neurodegenerative disorder, in that it is caused by a single genetic mutation and is amenable to predictive genetic testing, with estimation of years to predicted onset, enabling the entire range of disease ...
Aylward, EH +14 more
core
Effects of dance therapy on balance, gait and neuro-psychological performances in patients with Parkinson's disease and postural instability [PDF]
, 2012 Postural Instability (PI) is a core feature of Parkinson’s Disease (PD) and a major cause of falls and disabilities. Impairment of executive functions has been called as an aggravating factor on motor performances. Dance therapy has been shown effective
Agnetti, Virgilio +6 more
core
Alexander's disease and the story of Louise. [PDF]
, 2018 We describe the rare condition known as Alexander's disease or Alexander's leukodystrophy, which is essentially a childhood dementia. We then present the case of Louise Davies (we are using Louise's real name with the permission and special request of ...
Florschutz, G +2 more
core
Behavioral Genetics Research and Criminal DNA Databases [PDF]
, 2006 Kaye discusses DNA databanks and the potential use of such databanks for behavioral genetics research. He addresses the concern that DNA databanks serve as a limitless repository for future research and that the samples used in the databanks could be ...
Kaye, D. H.
core +2 more sources
SPATIAL MEMORY IN HUNTINGTON'S DISEASE: A COMPARATIVE REVIEW OF HUMAN AND ANIMAL DATA [PDF]
, 2016 Fink, Kyle D +4 more
core +1 more source
Making (anti-) sense out of huntingtin levels in Huntington disease [PDF]
, 2015 core +1 more source