Results 31 to 40 of about 6,618 (141)
Frontiers in Cell and Developmental Biology, 2021 One of the major Ca2+ signaling pathways is store-operated Ca2+ entry (SOCE), which is responsible for Ca2+ flow into cells in response to the depletion of endoplasmic reticulum Ca2+ stores.
Ewelina Latoszek, Magdalena Czeredys
doaj +1 more source
Incidence of adult Huntington's disease in the UK: a UK-based primary care study and a systematic review. [PDF]
, 2016 OBJECTIVES: The prevalence of Huntington's disease (HD) recorded in the UK primary care records has increased twofold between 1990 and 2010. This investigation was undertaken to assess whether this might be due to an increased incidence.
Collett, Laura +7 more
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Psychogenic non-epileptic seizures in early Huntington's disease [PDF]
, 2016 Huntington's disease (HD) is a neurodegenerative condition characterised by motor dysfunction with involuntary movements and loss of voluntary control, cognitive deterioration and psychiatric problems.
Rodrigues, FB, Wild, EJ
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Nutritional management of individuals with Huntington’s disease: nutritional guidelines [PDF]
, 2012 The delivery of good nutritional care is a fundamental element of the management of individuals with Huntington’s disease and all patients with Huntington’s disease will, at some time, need dietary intervention because of the sequela of the disease; yet ...
Brotherton, Ailsa M +5 more
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4472 Plasma Neurofilament Light as a Biomarker for Pediatric Patients with Huntington’s Disease
Journal of Clinical and Translational Science, 2020 OBJECTIVES/GOALS: The goal of this study is to compare plasma neurofilament light (NfL) concentrations in asymptomatic children and young adults that carry the gene expansion (GE group) that causes Huntington’s Disease to similar subjects that do not ...
Jordan L Schultz
doaj +1 more source
Cortical and Striatal Circuits in Huntington's Disease
, 2020 Huntington's disease (HD) is a hereditary neurodegenerative disorder that typically manifests in midlife with motor, cognitive, and/or psychiatric symptoms.
Blumenstock, S., Dudanova, I.
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“Clinical profile of genetically proven huntington's disease patients from Eastern India”
Annals of Indian Academy of Neurology, 2020 Background and Aims: To study the clinical profile of genetically proven Huntington's disease (HD) patients from eastern India. Methods: This cross sectional study selected patients of HD after genetic confirmation of expanded CAG repeats in Huntingtin ...
Zakir Hussain +8 more
doaj +1 more source
Neurobiology of Disease, 2012 The pathophysiology of Huntington's disease (HD) is primarily associated with striatal degeneration and a number of behavioral symptoms such as involuntary movements, cognitive decline, psychiatric disorders, and in the most juvenile-onset cases with ...
Michele Pignatelli +3 more
doaj +1 more source
Epigenetics and triplet-repeat neurological diseases [PDF]
, 2015 The term ‘junk DNA’ has been reconsidered following the delineation of the functional significance of repetitive DNA regions. Typically associated with centromeres and telomeres, DNA repeats are found in nearly all organisms throughout their genomes ...
Festenstein, RJ, Nageshwaran, S
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Advanced Science, EarlyView.Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély +5 more
wiley +1 more source