Results 101 to 110 of about 1,119,311 (215)

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, Volume 78, Issue 9, Page 1961-1974, September 2026.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source

Juvenile-onset Systemic Lupus Erythematosus: Recent Advances in Pathogenesis and Treatment

Current Rheumatology Reports
Abstract Purpose of Review This review summarizes recent advances in understanding the pathogenesis and therapeutic landscape of juvenile-onset systemic lupus erythematosus (jSLE), with a focus on how emerging genetic and immunologic insights inform patient stratification, targeted treatments ...
Natoli, Valentina, Charras, Amandine, Smith, Eve MD, Hedrich, Christian M.   +3 more
openaire   +2 more sources

Case report: Single infusion of combined anti-CD20 and anti-CD38 monoclonal antibodies in pediatric refractory lupus nephritis

Frontiers in Immunology
Lupus nephritis (LN), present in 30%–50% of systemic lupus erythematosus (SLE) patients, often necessitates standard immunosuppressive therapy (glucocorticoids, MMF, CYC) as suggested by the European League Against Rheumatism/European Renal Association ...
Decimo Silvio Chiarenza, Raul Mancini, Carolina Bigatti, Carolina Bigatti, Gianluca Caridi, Alessandro Consolaro, Alessandro Consolaro, Valentina Natoli, Valentina Natoli, Gabriele Mortari, Xhuliana Kajana, Francesca Lugani, Marco Gattorno, Marco Gattorno, Gian Marco Ghiggeri, Edoardo La Porta, Gabriele Gaggero, Enrico E. Verrina, Andrea Angeletti   +18 more
doaj   +1 more source

Hepatitis C virus antibodies in high risk juvenile onset systemic lupus erythematosus

Revista Brasileira de Reumatologia, 2016
Objective To evaluate the prevalence of hepatitis C virus (HCV) infection in high risk juvenile systemic lupus erythematosus (JSLE). Study design Forty low income JSLE patients (6M:34F; mean age 19 ± 4.4 yrs; mean disease duration 6 ± 3.2 yrs) were ...
Nádia E. Aikawa, Ana P. Nascimento, André L.S. Hayata, Eloisa Bonfá, Cláudia Goldenstein-Schainberg   +4 more
doaj   +1 more source

Problems of systemic connective tissue diseases of childhood in historical perspective

Научно-практическая ревматология
The relevance of study systemic connective tissue diseases with juvenile onset for modern medicine is determined by the trend towards their growth in the population, the difficulty of early diagnosis, the rapid development of disability and a poor life ...
M. I. Kaleda, I. P. Nikishina
doaj   +1 more source

Juvenile lupus-like with negative serology: a clinical dilemma and diagnostic challenge

Journal of Rheumatic Diseases
Systemic lupus erythematosus (SLE) is an autoimmune disorder that can affect various organs. Juvenile-onset SLE (jSLE) may be more severe than the adult-onset form, but the diagnosis and classification remain challenging due to the complex nature of the ...
Alhanouf Adnan Alsharif, Abdulaziz Marzouq Almutairi, Emtenan Badar Basahl, Abdulaziz Abdulllah Alshathri, Jameela Abdulaziz Kari, Mohammed Ahmad Shalaby, Mohammed Ahmad Nashawi   +6 more
doaj   +1 more source

Autoimmunity: Molecular Mechanisms, Biomarkers, and Therapeutic Opportunities

MedComm, Volume 7, Issue 9, September 2026.
Major types of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming involved in autoimmune diseases. The roles of immunometabolism, epigenetics, posttranscriptional regulation, and functional reprogramming in autoimmune diseases have been a major research focus in recent years.
Jialong Kuang, Yin Zhu, Fang Xu, Yongjing Liu, Yuan Li, Ling Yuan, Liqin Wei, Bo Huang, Yan Chen, Pei Huang, Zuochen Du   +10 more
wiley   +1 more source

IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study. [PDF]

, 2015
IgG anti-apolipoprotein A-1 (IgG anti-apoA-1) antibodies are present in patients with systemic lupus erythematosus (SLE) and may link inflammatory disease activity and the increased risk of developing atherosclerosis and cardiovascular disease (CVD) in ...
Davari, M, Yiannis Ioannou, Isenberg, D, Paul Bassett, Rahman, A, David Isenberg, Anisur Rahman, Maria Davari, Alber, KF, Ioannou, Y, Oliver Leach, Giles, I, Bassett, P, Karim Alber, Ian Giles, Leach, O, Sara Croca, Chambers, S, Croca, S, Sharon Chambers   +19 more
core   +1 more source

Other title: Final Report

, 2015
application/pdf; "November 2015."; Includes bibliographical references."Two recent reports called attention to the high costs and unsatisfactory outcomes of Kansas’s juvenile justice system. ...
Kansas Juvenile Justice Workgroup.
core   +1 more source

The future of Korean rheumatology

Journal of Rheumatic Diseases
Systemic lupus erythematosus (SLE) is an autoimmune disorder that can affect various organs. Juvenile-onset SLE (jSLE) may be more severe than the adult-onset form, but the diagnosis and classification remain challenging due to the complex nature of the ...
Bon San Koo, Jae-Bum Jun
doaj   +1 more source