Results 91 to 100 of about 1,185,551 (209)

Corpses as Repositories of Information and Funerals as Information Centres: Why Natural Selection Favours the Bereaved

Ethology, EarlyView.
Corpses are repositories of information about the cause of death. The distress of the bereaved acts as an honest signal drawing conspecifics to the body, enabling them to learn quickly about the death, adapt their behaviour, and spread knowledge of threats across multiple social levels.
Jacob Dembitzer, Dror Ben‐Ami
wiley   +1 more source

The Effect of PTPN22 Polymorphism on Juvenile Idiopathic Arthritis Subtypes and Disease Activity in a Finnish Study Population

International Journal of Immunogenetics, EarlyView.
ABSTRACT Genetic factors that modulate immune regulation are increasingly recognised as contributors to the heterogeneity and clinical course of autoimmune diseases. Polymorphisms of protein tyrosine phosphatase non‐receptor type 22 (PTPN22) are associated with several autoimmune diseases.
Sonja Kvist, Johanna Teräsjärvi, Heidi Rahikkala, Jussi Mertsola, Milja Möttönen, Qiushui He   +5 more
wiley   +1 more source

Involving young people in research investigating comorbidity associated with childhood-onset rheumatic disease: perspectives of a series of focus groups

BMC Rheumatology
Background Childhood-onset rheumatic diseases, such as juvenile idiopathic arthritis, juvenile-onset lupus and juvenile dermatomyositis, appear to be associated with an increased risk of comorbidities in adulthood compared to the general population.
Sab Siddiq, Jenny Sammy Ainsworth, Clare E. Pain, Eve M.D. Smith, Sizheng Steven Zhao, David M. Hughes, Liza J. McCann   +6 more
doaj   +1 more source

Childhood systemic lupus erythematosus in Latin America. The GLADEL experience in 230 children

, 2008
: To evaluate disease characteristics of childhood onset SLE in Latin America and to compare this information with an adult population in the same cohort of GLADEL.
D Wojdyla, MH Cardiel, Romero Grisales, Hugo de Jesús, Ramírez Gómez, Luis Alberto, Cardiel Ríos, Mario Humberto, O Uribe Uribe, H Grisales Romero, O Osio Uribe, BA Pons-Estel, Osio Uribe, Oscar, Pons Estel, Bernardo, LA Ramírez Gómez, Wojdyla, Daniel, Uribe Uribe, Oscar   +13 more
core   +1 more source

Management of Non‐Plaque‐Induced Gingival Conditions: A Systematic Review—Part 2: Inflammatory and Immune Conditions; Neoplasms; and Gingival Pigmentation

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra, Cecile Wasielewski, Bruno Špiljak, Maja Sabalić‐Schoener, Sebastien Jungo, Ivan Alajbeg   +5 more
wiley   +1 more source

Belimumab in the treatment of systemic lupus erythematosus with juvenile onset: Results of a single-center retrospective study

Научно-практическая ревматология
The treatment of systemic lupus erythematosus with juvenile onset (jSLE) remains a difficult task, taking into account the more aggressive course of the disease, requiring the appointment of various therapy regimens, including mainly a combination of ...
Maria I. Kaleda, Irina P. Nikishina, Tamari N. Pachkoria, Anna N. Shapovalenko   +3 more
doaj   +1 more source

Clinical predictors of proteinuric remission following an LN flare - evidence from the UK JSLE cohort study

Pediatric Rheumatology Online Journal, 2018
Background Proteinuria is a well-known risk factor for progression of renal dysfunction in a variety of chronic kidney diseases. In adult-onset Systemic Lupus Erytematosus (SLE) patients with lupus nephritis (LN), proteinuria takes a significant period ...
Eve M. D. Smith, Peng Yin, Andrea L. Jorgensen, Michael W. Beresford, on behalf of the UK JSLE Study Group   +4 more
doaj   +1 more source

Juvenile-onset Systemic Lupus Erythematosus: Recent Advances in Pathogenesis and Treatment

Current Rheumatology Reports
Abstract Purpose of Review This review summarizes recent advances in understanding the pathogenesis and therapeutic landscape of juvenile-onset systemic lupus erythematosus (jSLE), with a focus on how emerging genetic and immunologic insights inform patient stratification, targeted treatments ...
Natoli, Valentina, Charras, Amandine, Smith, Eve MD, Hedrich, Christian M.   +3 more
openaire   +2 more sources

Occurrence of infections in dogs receiving ciclosporin in a single‐centre UK referral population

Journal of Small Animal Practice, EarlyView.
Objectives The study aimed (a) to describe the occurrence and nature of new infections in dogs receiving oral ciclosporin and (b) to identify any risk factors associated with the development of a new infection whilst receiving ciclosporin. Materials and Methods In this retrospective cohort study, medical records of dogs presented to a private UK ...
S. Dormon, J. Walker, G. Gallow, L. Goonan, T. Sparks, A. Paul   +5 more
wiley   +1 more source

Case report: Single infusion of combined anti-CD20 and anti-CD38 monoclonal antibodies in pediatric refractory lupus nephritis

Frontiers in Immunology
Lupus nephritis (LN), present in 30%–50% of systemic lupus erythematosus (SLE) patients, often necessitates standard immunosuppressive therapy (glucocorticoids, MMF, CYC) as suggested by the European League Against Rheumatism/European Renal Association ...
Decimo Silvio Chiarenza, Raul Mancini, Carolina Bigatti, Carolina Bigatti, Gianluca Caridi, Alessandro Consolaro, Alessandro Consolaro, Valentina Natoli, Valentina Natoli, Gabriele Mortari, Xhuliana Kajana, Francesca Lugani, Marco Gattorno, Marco Gattorno, Gian Marco Ghiggeri, Edoardo La Porta, Gabriele Gaggero, Enrico E. Verrina, Andrea Angeletti   +18 more
doaj   +1 more source