Results 71 to 80 of about 1,185,551 (209)

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Mental disorders in children with rheumatic diseases

Научно-практическая ревматология
The prevalence of concomitant mental disorders in children with rheumatic diseases is notably higher than in the overall population. However, psychiatric comorbidity in pediatric rheumatology remains poorly understood, whereas approaches to mental ...
A. V. Santimov, S. V. Grechanyi, G. A. Novik   +2 more
doaj   +1 more source

Nail Disorders in Systemic Conditions

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail findings in children can be indicative of an underlying systemic disease. Many of these findings are seen in multiple entities and are not specific to one disease. The importance of specifically examining for these nail changes cannot be overstated.
Jane Sanders Bellet
wiley   +1 more source

Across ancestries, HLA-B∗08:01∼DRB1∗03:01 (DR3) and HLA-DQA∗01:02 (DR2) increase the risk to develop juvenile-onset systemic lupus erythematosus through low complement C4 levels

Journal of Translational Autoimmunity
Objective: Systemic lupus erythematosus (SLE) is a systemic autoimmune/inflammatory disease with a strong genetic component. Genetic burden is higher in children when compared to patients with adult-onset SLE, contributing to earlier disease expression ...
Yves Renaudineau, Amandine Charras, Valentina Natoli, Nicolas Congy-Jolivet, Sam Haldenby, Xuan Liu, Yongxiang Fang, Eve MD. Smith, Michael W. Beresford, Christian M. Hedrich, Carla Roberts, Eslam Al-Abadi, Kate Armon, Kathryn Bailey, Coziana Ciurtin, Janet Gardner-Medwin, Kirsty Haslam, Daniel P. Hawley, Alice Leahy, Valentina Leone, Flora McErlane, Gita Modgil, Clarissa Pilkington, Athimalaipet V. Ramanan, Satyapal Rangaraj, Phil Riley, Arani Sridhar   +26 more
doaj   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Childhood-onset bullous systemic lupus erythematosus

, 2014
Bullous systemic lupus erythematosus has rarely been described in pediatric lupus population and the real prevalence of childhood-onset bullous systemic lupus erythematosus has not been reported.
Campos, L. M. A., Romiti, R., Aikawa, N. E., Lourenco, D. M. R., Gomes, R. Cunha, Silva, C. A.   +5 more
core   +1 more source

Toll‐Like Receptor 4 Signaling in Natural N‐Acylethanolamines and Derivative NAE‐Like Compounds: Mechanisms and Implications for Neuroimmune and Inflammatory Processes in a Systematic Search Approach

Phytotherapy Research, EarlyView.
ABSTRACT N‐acylethanolamines (NAEs) are endogenous fatty acid amides structurally related to the endocannabinoid anandamide and function as bioactive lipid mediators with broad regulatory roles in inflammation and neuroinflammation. Among pattern‐recognition receptors, Toll‐like receptor 4 (TLR4) occupies a central position in innate immune ...
Damiana Scuteri, Francesca Guida, Giacinto Bagetta, Sabatino Maione, Maria Tiziana Corasaniti, Morena Zusso   +5 more
wiley   +1 more source

Eating disorders in children with rheumatic diseases

Научно-практическая ревматология
The high comorbidity of eating disorders, especially anorexia nervosa, and various autoimmune diseases is well known but only a few foreign publications address the prevalence and course of eating disorders in children with immuneinflammatory rheumatic ...
A. V. Santimov, S. V. Grechanyi, G. A. Novik, M. V. Zhdanova, N. V. Slizovskii   +4 more
doaj   +1 more source

Macrophage activation syndrome triggered by systemic lupus erythematosus flare: successful treatment with a combination of dexamethasone sodium phosphate, intravenous immunoglobulin, and cyclosporine: a case report

Journal of Medical Case Reports, 2021
Background Macrophage activation syndrome is classified as a secondary form of hemophagocytic lymphohistiocytosis. It is a hyperinflammatory complication observed to be comorbid with a variety of autoimmune diseases, including adult-onset Still’s disease
Wesam Gouda, Faisal Alsaqabi, Abdelhfeez Moshrif, Awad S. Abbas, Tarek M. Abdel-Aziz, Md Asiful Islam   +5 more
doaj   +1 more source

Irreversible blindness in juvenile systemic lupus erythematosus

, 2011
Blindness caused by severe vasculitis or uveitis is rare in juvenile systemic lupus erythematosus (JSLE) patients. In a 27-year period, 5367 patients were followed at our Paediatric Rheumatology Division and 263 (4.9%) patients had JSLE (American College
AIKAWA, N. E., SILVA, C. A., SALLUM, A. M. E., JESUS, A. A., ALMEIDA, R. T., SA, L. C. F.   +5 more
core   +1 more source