Results 51 to 60 of about 1,119,311 (215)

Alveolar hemorrhage: distinct features of juvenile and adult onset systemic lupus erythematosus

, 2012
We compared outcomes of alveolar hemorrhage (AH) in juvenile (JSLE) and adult onset SLE (ASLE). From 263 JSLE and 1522 ASLE, the AH occurred in 13 (4.9%) and 15 (1.0%) patients, respectively (p < .001). Both groups had comparable disease duration (2.6
Campos, L. M. A., Araujo, D. B., Bonfa, E., Borba, E. F., Pereira, R. M. R., Shinjo, S. K., Silva, C. A.   +6 more
core   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Hepatitis A virus vaccination in childhood-onset systemic lupus erythematosus

, 2019
Objectives: Vaccination of systemic lupus erythematosus patients with non-live vaccines may decrease vaccine-preventable infections and mortalities.
Adrovic, A., Barut, K., Kasapcopur, O., Yuksel, P., Sahin, S., Kocazeybek, B. S., Sazak, S., Mertoglu, S., Beser, O. F.   +8 more
core   +1 more source

Carrion ecology: concepts, interdisciplinary synthesis, and perspectives

Biological Reviews, EarlyView.
ABSTRACT Carrion is a ubiquitous resource in both terrestrial and aquatic ecosystems, yet it has long been overlooked in ecological research. Over the past two decades, studies on carrion and the many organisms that exploit it have flourished, revealing not only wide‐ranging ecological functions but also significance far beyond ecology.
Marcos Moleón, José A. Sánchez‐Zapata, Travis L. DeVault, Wayne M. Getz, Zebensui Morales‐Reyes, Daniel Redondo‐Gómez, Lara Naves‐Alegre, Solange A. Batista‐Nunes, Esther Sebastián‐González, Juan M. Pérez‐García, Kelly A. Waters, Thijs van Overveld, Craig Smith, Nuria Selva, Thomas A. Schlacher, Graeme Ruxton, Jesús Rodríguez, Martina‐M. Quaggiotto, Paula L. Perrig, Norman Owen‐Smith, Thomas M. Newsome, Isabel Navas, Yoshihiro Nakashima, Ana Mateos, Carlos Martínez‐Carrasco, Daniel Martín‐Vega, Berta Martín‐López, Antoni Margalida, Sergio A. Lambertucci, Adam Kane, Kevin Healy, Akane Hashizume, Antonio J. García‐Fernández, José A. Donázar, M. Eric Benbow, James C. Beasley, Philip S. Barton, Kathleen A. Alexander, Eneko Arrondo   +38 more
wiley   +1 more source

Juvenile-onset systemic lupus erythematosus: different clinical and serological pattern than adult-onset systemic lupus erythematosus.

, 2009
OBJECTIVE: To investigate differences in clinical signs and symptoms, and in antinuclear antibodies (ANA), between patients with juvenile-onset and adult-onset systemic lupus erythematosus (SLE). METHODS: Clinical and serological data of 56 patients with
Joos, Rik, Isenberg, D, Elewaut, D., Hoffman, I E A, Houssiau, Frédéric, Lauwerys, BR, Huizinga, T W J, Cebecauer, L, Hoffman, IEA, De Keyser, Filip, Lauwerys, Bernard, De Keyser, F., Dehoorne, J, Dehoorne, Jo, Hendrickx, G, Huizinga, TWJ, Elewaut, Dirk, Joos, R, Houssiau, F, Isenberg, D.   +19 more
core   +1 more source

Urinary HER2, TWEAK and VCAM-1 levels are associated with new-onset proteinuria in paediatric lupus nephritis

Lupus Science and Medicine, 2022
Objective Lupus nephritis is a key driver of morbidity and mortality in SLE. Detecting active nephritis on a background of pre-existing renal damage is difficult, leading to potential undertreatment and accumulating injury.
Michelle A Petri, Emily von Scheven, Marisa S Klein-Gitelman, Patricia Costa-Reis, Kelly Maurer, Kathleen E Sullivan, Daniella Levy Erez, Xue Zhao, Walter Faig, Jon Burnham, Kathleen O'Neil   +10 more
doaj   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Childhood systemic lupus erythematosus in Latin America. The GLADEL experience in 230 children

, 2008
: To evaluate disease characteristics of childhood onset SLE in Latin America and to compare this information with an adult population in the same cohort of GLADEL.
D Wojdyla, MH Cardiel, Romero Grisales, Hugo de Jesús, Ramírez Gómez, Luis Alberto, Cardiel Ríos, Mario Humberto, O Uribe Uribe, H Grisales Romero, O Osio Uribe, BA Pons-Estel, Osio Uribe, Oscar, Pons Estel, Bernardo, LA Ramírez Gómez, Wojdyla, Daniel, Uribe Uribe, Oscar   +13 more
core   +1 more source

Autoantibody-based subgroups and longitudinal seroconversion in juvenile-onset systemic lupus erythematosus

Lupus Science and Medicine, 2023
Objective To explore the clinical value of autoantibody-based subgroup framework and the trend of autoantibody fluctuation in juvenile-onset SLE (JSLE).Methods Eighty-seven patients with JSLE were retrospectively collected and divided into subgroups via ...
Zhen Yang, Fei Ding, Chenxi Liu, Jingyi Lu, Hua Huang, Shengfang Bao, Yingying Jin, Xuemei Xu, Yanliang Jin   +8 more
doaj   +1 more source

Multi‐omics–driven precision medicine

iMeta, EarlyView.
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li, Zhe Zhao, Yifan Zhang, Yao Ma, Gaofei Hu, Min Zeng, Zhanqun Yang, Zixuan Zhao, Xin Zhou, Wei Hu, Yuxuan Sun, Meng Su, Jun Li, Matthew Whiteman, Wei Fu, Chao Zhong, Lemin Zheng, Long Chen, Hairong Lv, Rongsheng Zhao, Yi Zhun Zhu   +20 more
wiley   +1 more source