Results 41 to 50 of about 1,119,311 (215)

Predictors of remission on therapy in the juvenile-onset systemic lupus erythematosus patients.

open access: yes, 2022
Predictors of remission on therapy in the juvenile-onset systemic lupus erythematosus patients.
Butsabong Lerkvaleekul (12055191)   +5 more
core   +1 more source

Assessment of damage in juvenile‐onset systemic lupus erythematosus: A multicenter cohort study [PDF]

open access: yesArthritis Care & Research, 2003
AbstractObjectiveTo investigate the prevalence of cumulative organ damage in patients with juvenile‐onset systemic lupus erythematosus (SLE) and its association with demographic and clinical variables, medication use, and quality of life.MethodsThe occurrence of organ system damage, as measured by the Systemic Lupus International Collaborating Clinics ...
RAVELLI, ANGELO   +14 more
openaire   +3 more sources

Validation of Patient‐Reported Outcomes Measurement Information System (PROMIS) Pediatric Measures for Children With Chronic Nonbacterial Osteomyelitis

open access: yesArthritis Care &Research, EarlyView.
Objective To assess the validity of the Patient‐Reported Outcomes Measurement Information System (PROMIS) Pediatric measures in patients with chronic nonbacterial osteomyelitis (CNO). Methods Within the longitudinal patient registry of CNO, English‐speaking patients aged 8 years and older self‐reported PROMIS Pediatric measures of fatigue, pain ...
Mary M. Eckert   +43 more
wiley   +1 more source

Exome Sequencing Uncovers Phenotypic and Genotypic Heterogeneity in 196 Indian Families Evaluated for Autoinflammatory Disorders

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autoinflammatory disorders (AIDs) are a clinically heterogeneous group of inborn errors of immunity primarily caused by dysregulation in the innate immune system. Clinical diagnosis is often challenging due to clinical heterogeneity and the overlapping phenotypes with other inborn errors of immunity and monogenic conditions that mimic AIDs ...
Vaishnavi Ashok Badiger   +28 more
wiley   +1 more source

Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study [PDF]

open access: yes, 2005
Juvenile rheumatoid arthritis (JRA) comprises a group of chronic systemic inflammatory disorders that primarily affect joints and can cause long-term disability.
Woo, P   +9 more
core  

Kawasaki disease and juvenile systemic lupus erythematosus

open access: yes, 2012
Kawasaki disease (KD) is a common vasculitis in childhood. To the authors' knowledge, only one case of juvenile systemic lupus erythematosus (JSLE)-like onset mimicking KD and another case of KD and JSLE association have previously been described ...
Almeida, R. T.   +5 more
core   +1 more source

CAR-T cell therapy for juvenile-onset autoimmune diseases: a promising future?

open access: yesArthritis Research & Therapy
Chimeric antigen receptor (CAR) T-cell therapy targeting B cells has shown promising results, including drug-free remission, in adult-onset autoimmune diseases.
Maurine Jouret   +7 more
doaj   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

open access: yesArthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz   +13 more
wiley   +1 more source

Outcome of Early Onset Systemic Lupus Erythmatosus - A Tertiary Care Study

open access: yesPakistan Armed Forces Medical Journal
Objective: To evaluate the outcome of early onset systemic lupus erythematosus at tertiary care centre. Study Design: A cross sectional study. Place and Duration of Study: Combined Military Hospital, Kharian Pakistan, from Feb 2021 to Jan 2024 ...
Iffat Rafique   +5 more
doaj   +1 more source

Pharmacokinetics, Effectiveness and Safety of Certolizumab Pegol in Children and Adolescents With Active Juvenile Idiopathic Arthritis: 9+‐Year Results From a Multicenter, Open‐Label Study

open access: yesArthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients aged 2 to 17 years with ...
Hermine I. Brunner   +52 more
wiley   +1 more source

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