Results 41 to 50 of about 1,185,551 (209)

Neuropsychiatric lupus in Malaysian children: clinical characteristics, imaging features and 12-month outcomes

The Turkish Journal of Pediatrics, 2021
Background. Neuropsychiatric lupus (NPSLE) serves as a marker of severe disease in children with juvenile onset systemic lupus erythematosus (JSLE). This study aims to characterise the clinical and imaging features at diagnosis; and outcomes after
Sern Chin Lim, Yusma Lyana Md-Yusof, Bushra Johari, Roqiah Fatmawati Abdul-Kadir, Swee Ping Tang   +4 more
doaj   +1 more source

Mucocutaneous manifestations in juvenile-onset systemic lupus erythematosus: a review of literature [PDF]

Pediatric Rheumatology, 2015
Patients diagnosed with juvenile-onset systemic lupus erythematosus (JSLE) often have skin and oral lesions as part of their presentation. These mucocutaneous lesions, as defined by the American College of Rheumatology (ACR) in 1997, include malar rash, discoid rash, photosensitivity and oral ulcers. It is therefore essential to recognize mucocutaneous
Chiewchengchol, Direkrit, Murphy, Ruth, Edwards, Steven W, Beresford, Michael W   +3 more
openaire   +2 more sources

Bone mineral density in juvenile onset Systemic lupus erythematosus

Indian Pediatrics, 2015
To compare bone mineral density in patients with juvenile-onset Systemic lupus erythematosus and healthy controls.Serial bone mineral density measurements in 27 patients with juvenile-onset systemic lupus were compared to 97 healthy age-matched controls.All patients with juvenile-onset had low bone mineral density scores at initial assessment that ...
R, Abdwani, E, Abdulla, S, Yaroubi, H, Bererhi, I, Al-Zakwani   +4 more
openaire   +2 more sources

Depression Risk in Young Adults With Juvenile- and Adult-Onset Lupus: Twelve Years of Followup [PDF]

, 2018
OBJECTIVE: To compare major depression risk among young adults with juvenile-onset and adult-onset systemic lupus erythematosus (SLE), and to determine demographic and health-related predictors of depression.
Trupin, Laura, Erica F. Lawson, Laura Trupin, Lawson, Erica F, Andrea M. Knight, Knight, Andrea M, Patricia Katz, Katz, Patricia, Yelin, Edward, Edward Yelin   +9 more
core   +1 more source

Case Report: Novel UNC93B1 variant causes rheumatoid arthritis and interstitial pneumonia

Frontiers in Immunology
BackgroundUNC93B1 is a transmembrane protein essential for regulating toll-like receptors (TLRs). Pathogenic variants in human UNC93B1 have recently been described in a limited number of patients with childhood systemic lupus erythematosus and chilblain ...
Tingyan He, Junbin Ou, Lijuan Huang, Xinyi Zhou, Linlin Wang, Xiaolin Li, Jun Yang   +6 more
doaj   +1 more source

Exome sequencing enables molecular diagnosis in 10% of early-onset or familial systemic lupus erythematosus cases. [PDF]

EBioMedicine
International audienceBackground Systemic lupus erythematosus (SLE) is a chronic, multi-organ autoimmune disease characterised by a highly heterogeneous presentation.
Tusseau M, Khaldi-Plassart S, Labalme A, Mathieu AL, Riller Q, Molitor C, Simonet T, Viel S, Gaboriaud C, Thielens N, Heiser L, Chopin E, Rouvet I, Fabien N, Goncalves D, Fremeaux-Bacchi V, El-Sissy C, Pottier N, Larrue R, Ranchin B, Laurent A, Fouillet-Desjonqueres M, Jouret M, Mekinian A, Yamashita M, Morio T, Hachulla E, Melki I, Kone-Paut I, Ballot C, Reumaux H, Pillet P, Harambat J, Richez C, Richer O, Hatchuel Y, Louillet F, Lega JC, Durieu I, Welfringer-Morin A, Picard C, Messadi W, Sarrot-Reynauld F, Sanlaville D, Bader-Meunier B, Walzer T, Lesca G, Rieux-Laucat F, Belot A, GENIAL/LUMUGENE Collaborators.   +49 more
europepmc   +2 more sources

Supplemental material for The effectiveness and safety of biological therapeutics in juvenile-onset systemic lupus erythematosus (JSLE): a systematic review

, 2018
Supplemental material for The effectiveness and safety of biological therapeutics in juvenile-onset systemic lupus erythematosus (JSLE): a systematic review by E Peterknecht, M P Keasey and M W Beresford in ...
E Peterknecht (5876006), M W Beresford (5876012), M P Keasey (5876009)   +2 more
core   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

AB0481 Vitamin D Levels in Children, Adolescents, and Young Adults with Juvenile Onset Systemic Lupus Erythematosus: A Transversal Study

, 2014
Vitamin D Levels in Children, Adolescents, and Young Adults with Juvenile Onset Systemic Lupus Erythematosus: A Transversal ...
Lepri, Gemma, Matucci Cerinic, Marco, Stagi, Stefano, Cavalli, Loredana, Brandi, Maria Luisa, Bertini, Federico, Falcini, Fernanda   +6 more
core   +1 more source

Exome Sequencing Uncovers Phenotypic and Genotypic Heterogeneity in 196 Indian Families Evaluated for Autoinflammatory Disorders

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autoinflammatory disorders (AIDs) are a clinically heterogeneous group of inborn errors of immunity primarily caused by dysregulation in the innate immune system. Clinical diagnosis is often challenging due to clinical heterogeneity and the overlapping phenotypes with other inborn errors of immunity and monogenic conditions that mimic AIDs ...
Vaishnavi Ashok Badiger, Periyasamy Radhakrishnan, Suma Balan, Anand P. Rao, Prajna Udupa, Karthik Vijay Nair, Bhagesh Hunakunti, Adarsh Pooradan Prasannakumar, Sanket Limaye, Huzail Gani Shaikh, Rohit Naik, Mahesh Janarthanan, Sudharshan Sridharan, Vishal Sondhi, Sheela Nampoothiri, Hitesh Shah, Sabrinath Mahadevan, Mahabaleshwar Mamadapur, Devang Pandya, Katta Mohan Girisha, Abhay Shivpuri, Amita Moirangthem, Jyothi Raghuram, Gandham Sri Lakshmi Bhavani, Sachin Jeevanagi, Girish Subramaniam, Amita Aggarwal, Anju Shukla, Dhanya Lakshmi Narayanan   +28 more
wiley   +1 more source