Results 21 to 30 of about 1,119,311 (215)

Quality of life in patients with juvenile-onset systemic lupus erythematosus

Journal of V. N. Karazin Kharkiv National University: Series Medicine
Background. Childhood-onset systemic lupus erythematosus (cSLE) is a rare, multisystem, and potentially life-threatening autoimmune disease with significant comorbidities and the development of a chronic, debilitating condition for the patient.
L.F. Bohmat, N.S. Shevchenko, I.M. Bessonova, T.O. Holovko   +3 more
doaj   +2 more sources

Effectiveness of Belimumab for Glucocorticoid Discontinuation in Juvenile-Onset Lupus Nephritis. [PDF]

Indian J Nephrol
Lupus nephritis (LN) is an important complication of systemic lupus erythematosus, for which glucocorticoids (GCs) are the primary treatment. Due to the side effects associated with GCs, their long-term use should ideally be tapered and discontinued. At present, no such possibility exists without problematic flares after discontinuation.
Kise T, Uehara M.
europepmc   +3 more sources

Juvenile-onset multifocal osteonecrosis in systemic lupus erythematosus

Medicine, 2021
Abstract Rationale: Osteonecrosis (ON) is a devastating illness that leads to bone ischemia and potential joint destruction. Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease, with multi-system involvement which is closely associated with occurrence of ON.
Jin, Wenyuan, Yang, Xinghui, Lu, Meiping
openaire   +2 more sources

Rituximab therapy for juvenile-onset systemic lupus erythematosus [PDF]

Pediatric Nephrology, 2007
Rituximab (RTX), an anti-CD20 monoclonal antibody, has been proposed for use in the therapy of systemic lupus erythematosus (SLE). We present the initial long-term experience of the safety and efficacy of rituximab for treatment of SLE in children.
Nwobi, Obioma, Abitbol, Carolyn L., Chandar, Jayanthi, Seeherunvong, Wacharee, Zilleruelo, Gastón   +4 more
openaire   +2 more sources

Difference in clinical profile between juvenile onset and adult-onset systemic lupus erythematosus: a meta-analysis [PDF]

, 2021
The aim was to systematically review the studies that compared clinical and serological variation between adult-onset systematic lupus erythematosus (aSLE) andjuvenile-onset systematic lupus erythematosus (jSLE).
Goghawala, Gayatri Anand, Patel, Kaushal, Abbas, Kiran, Shah, Parshwa Keyur, Patel, Harshil Devang, Srivastava, Puja, Shah, Mihika Ashish, Pandya, Sapan C., Shah, Mandar Kalpesh, Kathayat, Priyangi Manohar, Shah, Sharan Dharmesh   +10 more
core   +1 more source

The role of neutrophil apoptosis in juvenile‐onset systemic lupus erythematosus [PDF]

Arthritis & Rheumatism, 2009
AbstractObjectiveAccumulation of apoptotic cells may lead to the development of systemic lupus erythematosus (SLE) through a breakdown in immune tolerance. Altered neutrophil apoptosis may contribute to nuclear autoantigen exposure, ultimately leading to autoantibody generation.
Angela, Midgley, Zoe, McLaren, Robert J, Moots, Steven W, Edwards, Michael W, Beresford   +4 more
openaire   +2 more sources

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Juvenile systemic lupus erythematosus presenting only as nonscarring alopecia

Indian Journal of Paediatric Dermatology, 2022
Juvenile onset systemic lupus erythematosus (JSLE) is a rare multisystem, autoimmune disorder. Alopecia in SLE generally follows a pre-established disease with systemic symptoms. A 13-year-old girl presented with sudden hair loss over the vertex of scalp
N M Vinitha, Reena Rai, G Uma Maheswari
doaj   +1 more source

Juvenile-onset systemic lupus erythematosus in Malay children

Saudi Medical Journal, 2018
[No abstract available].
Ali S, Jawad, Wan Zuraida W A, Hamid
openaire   +2 more sources

Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: A multicenter study

Joint Bone Spine, 2023
Neuropsychiatric (NP) involvement is a restricted area in juvenile-onset systemic lupus erythematosus (jSLE).To investigate the prevalence, demographic and clinical features, and outcomes of the neurological involvement in the Turkish jSLE population.This study was based upon 24 referral centers' SLE cohorts, multicenter and multidisciplinary network ...
Poyrazoğlu, Muammer H, Kısaarslan, Ayşenur Paç, Çiçek, Sümeyra Özdemir, Batu, Ezgi D, Şahin, Sezgin, Gürgöze, Metin K, Çetinkaya, Sibel Balcı, Ekinci, Miray Kışla, Atmış, Bahriye, Barut, Kenan, Adrovic, Amra, Ağar, Buket Esen, Şahin, Nihal, Demir, Ferhat, Bağlan, Esra, Kara, Mehtap Akbalık, Selçuk, Şenay Zırhlı, Özdel, Semanur, Çomak, Elif, Akkoyunlu, Betül, Yener, Gülçin Otar, Öztürk, Kübra, Yıldız, Mehmet, Haşlak, Fatih, Şener, Seher, Kısaoğlu, Hakan, Baba, Özge, Kızıldağ, Zehra, İşgüder, Rana, Çağlayan, Şengül, Güven Bilgin, Raziye B, Aytaç, Gülçin, Yücel, Burcu Bozkaya, Tanatar, Ayşe, Sönmez, Hafize E, Çakan, Mustafa, Kara, Aslıhan, Elmas, Ahmet T, Kılıç, Beltinge Demircioğlu, Ayaz, Nuray Aktay, Kasap, Belde, Acar, Banu Çelikel, Ozkaya, Ozan, Yüksel, Selçuk, Aydoğ, Özlem, Aksu, Güzide, Akman, Sema, Dönmez, Osman, Bülbül, Mehmet, Büyükçelik, Mithat, Tabel, Yılmaz, Sözeri, Betül, Kalyoncu, Mukaddes, Bilginer, Yelda, Ünsal, Erbil, Kasapçopur, Özgür, Özen, Seza, Düşünsel, Ruhan, Yıldırım, DENİZ, Bakkaloğlu, SEVCAN AZİME   +59 more
openaire   +12 more sources