Results 221 to 230 of about 54,427 (263)

Bone Mineral Density and Serum Vitamin D 25-hydroxyvitamin D Levels in Childhood- or Juvenile-onset Systemic Lupus Erythematosus: A Systematic Review and Meta-analysis

Academic and Clinical Pediatrics
Patients with systemic lupus erythematosus (SLE), particularly those with childhood or juvenile onset, face a higher risk of complications due to low bone mineral density (BMD) and reduced serum Vitamin D levels. The aim of this study was to
Leonardo Alpha Diaz, Vanessa Els, Ni Wayan Puspita Sari, Madeline Juliand Sitranata, R. Suteja, Ketut Dewi Kumara Wati   +5 more
semanticscholar   +1 more source

Disease modifying immunosuppressant drugs for juvenile-onset systemic lupus erythematosus

Cochrane Database of Systematic Reviews, 2010
This is the protocol for a review and there is no abstract. The objectives are as follows: To summarise the evidence from randomised controlled trials for the effectiveness and safety of DMARDs in the treatment of juvenile-onset systemic lupus erythematosus, specifically: To quantify the effects of DMARDs on disease activity, health related ...
Craig, Jean V., Pain, Clare E., Beresford, Michael William   +2 more
openaire   +2 more sources

Renal biomarkers in Juvenile-onset systemic lupus erythematosus

2013
Background: Juvenile-onset Systemic Lupus Erythematosus (JSLE) is a rare, but severe, autoimmune condition with lupus nephritis (LN) occurring in up to 80% of patients and predisposing to an increased mortality. Aims/Objectives: As part of the UK JSLE Cohort Study this study aimed to identify whether standard and/or novel biomarkers are useful for ...
openaire   +1 more source

Juvenile-onset systemic lupus erythematosus: how to diagnose and manage

Paediatrics and Child Health, 2015
Abstract Systemic lupus erythematosus (SLE) is the prototypic autoimmune disorder, characterised by auto-antibody production against nuclear antigens. Juvenile-onset systemic lupus erythematosus (JSLE) is a more severe form than the adult-onset disease, with a more balanced gender ratio.
Louise Oni, Colin Thorbinson, Michael W. Beresford   +2 more
openaire   +1 more source

Serious infections and tuberculosis adversely impact outcomes of juvenile onset systemic lupus erythematosus in India

Lupus
Background Infections are a major cause of morbidity and mortality in juvenile systemic lupus erythematosus (SLE). We assessed the incidence and risk factors for major infections in juvenile SLE. Methods A retrospective review of 225 patients of juvenile
Rudrarpan Chatterjee, S. Pattanaik, D. Misra, V. Agarwal, Able Lawrence, Ramnath Misra, A. Aggarwal   +6 more
semanticscholar   +1 more source

Genetic and epigenetic factors shape phenotypes and outcomes in systemic lupus erythematosus – focus on juvenile-onset systemic lupus erythematosus

Current Opinion in Rheumatology
Purpose of review Systemic lupus erythematosus (SLE) is a severe autoimmune/inflammatory disease. Patients with juvenile disease-onset and those of non-European ancestry are most severely affected.
A. Charras, Linda T Hiraki, Laura B Lewandowski, C. Hedrich   +3 more
semanticscholar   +1 more source

The unseen onset: myelitis and nephritis as the first clue to juvenile lupus

International Journal of Contemporary Pediatrics
Juvenile systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder that commonly affects the kidneys and central nervous system. While lupus nephritis and neuropsychiatric manifestations are well-recognized complications, the concurrent ...
Sreeja Mogiligari, Vijayaraju Parimi
semanticscholar   +1 more source

Juvenile onset systemic lupus erythematosus thyroid dysfunction: A subgroup with mild disease?

Journal of Autoimmunity, 2009
The aim of this study was to evaluate the frequency of thyroid dysfunction and thyroid antibodies in patients with juvenile onset Systemic Lupus Erythematosus (JOSLE) and its association with clinical and immunological features. Seventy-seven patients with JOSLE, 64 females, median age 19 years, were consecutively enrolled from March to December 2007 ...
Luciana, Parente Costa, Eloisa, Bonfá, Ciro D, Martinago, Ricardo M, de Oliveira, Jozélio Freire, Carvalho, Rosa M R, Pereira   +5 more
openaire   +2 more sources

HLA-DRB1 antigens in Taiwanese patients with juvenile-onset systemic lupus erythematosus

Rheumatology International, 2001
This study was done to investigate the frequency of HLA-DRB1 antigens in juvenile-onset systemic lupus erythematosus (SLE) in the Taiwanese population.Thirty-four Taiwanese patients with juvenile onset SLE and 200 unrelated healthy controls were studied.
J L, Huang, C K, Shaw, A, Lee, T D, Lee, Y H, Chou, M L, Kuo   +5 more
openaire   +2 more sources

A Study on Semaphorin 3A Level in Juvenile-onset Systemic Lupus Erythematosus Patients.

Current Rheumatology Reviews
BACKGROUND Juvenile-onset systemic lupus erythematosus (jSLE) is an uncommon yet severe autoimmune/inflammatory condition affecting multiple bodily systems, typically manifest-ing before the age of 18.
Huda Marzouk, Dina Hesham Ahmed, Hend Mohamed Abu Shady, Hussien Tarek Abdelrahman Sarhan, Mohamed Salah Eldin Mohamed AbdelKader   +4 more
semanticscholar   +1 more source