Results 1 to 10 of about 1,352 (181)
Limited sensitivity and specificity of the ACR/EULAR-2019 classification criteria for SLE in JSLE?—observations from the UK JSLE Cohort Study [PDF]
Rheumatology, 2021 Abstract Objectives This study aimed to test the performance of the new ACR and EULAR criteria, that include ANA positivity as entry criterion, in JSLE. Methods Performance of the ACR/EULAR-2019 criteria were compared with Systemic ...
Robert Moots +2 more
exaly +12 more sources
Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus (jSLE)
Molecular and Cellular Pediatrics, 2023 Systemic lupus erythematosus (SLE) is a rare autoimmune/inflammatory disease with significant morbidity and mortality. Approximately 15–20% of SLE patients develop the disease during childhood or adolescence (juvenile-onset SLE/jSLE).
Valentina Natoli +3 more
doaj +4 more sources
Differential analysis of serum and urine S100 proteins in juvenile-onset systemic lupus erythematosus (jSLE) [PDF]
Clinical Immunology, 2020 Up to 80% of juvenile-onset systemic lupus erythematosus (jSLE) patients develop lupus nephritis (LN) that affects treatment and prognosis. Easily accessible biomarkers do not exist to reliably diagnose LN, leaving kidney biopsies as the gold-standard.
Christian Hedrich +2 more
exaly +4 more sources
P3 Is there a relationship between lupus anticoagulant autoantibody and fatigue in jSLE? [PDF]
Poster presentations, 2020 Background Fatigue is a common symptom in systemic lupus erythematosus (SLE) and is associated with poorer quality of life and higher depression scores. Lupus anticoagulant (AcL) refers to a subset of autoantibodies to phospholipids interfering with clotting tests, which major clinical association is thrombosis.
Margarida Figueiredo-Braga +2 more
exaly +2 more sources
Clinical predictors of active LN development in children – evidence from the UK JSLE Cohort Study
Lupus, 2018 Background Juvenile-onset systemic lupus erythematosus (JSLE) patients may develop lupus nephritis (LN) during their initial presentation, or later in their disease. This study aimed to assess whether clinical/demographic factors characterize patients with LN within the United Kingdom JSLE Cohort Study, and ...
Michael William Beresford +2 more
exaly +3 more sources
1675 Real world treatment of juvenile systemic lupus erythematosus (JSLE): evidence from the UK JSLE cohort study [PDF]
Abstracts, 2021 Christian Hedrich +2 more
exaly +2 more sources
Lupus, 2018 Objective To systematically review and summarize the available literature regarding the effectiveness and safety of biologics in the treatment of juvenile-onset systemic lupus erythematosus. Methods PubMed was systematically searched ...
Matthew Keasey +1 more
exaly +4 more sources
Global prevalence of JIA, JSLE and club foot [PDF]
Nature Reviews Rheumatology, 2020 Jessica McHugh
exaly +3 more sources
European Journal of Investigation in Health, Psychology and Education, 2021 Juvenile systemic lupus erythematosus (JSLE) is diagnosed in children younger than 18 years of age. Depression and anxiety are common, but not well understood in JSLE.
Margarida Figueiredo-Braga +6 more
doaj +1 more source