Results 1 to 10 of about 732 (166)

Neuropsychiatric Involvement in Juvenile-Onset Systemic Lupus Erythematosus (jSLE)

Molecular and Cellular Pediatrics, 2023
Systemic lupus erythematosus (SLE) is a rare autoimmune/inflammatory disease with significant morbidity and mortality. Approximately 15–20% of SLE patients develop the disease during childhood or adolescence (juvenile-onset SLE/jSLE).
Valentina Natoli, Amandine Charras, Christian M Hedrich   +2 more
exaly   +4 more sources

An Unprecedented Triad: Simultaneous Acute Pancreatitis, Axonal Polyneuropathy, and Type 1 Diabetes Mellitus in a Catastrophic Juvenile Lupus Flare [PDF]

Clinical Case Reports
A 14‐year‐old female with juvenile systemic lupus erythematosus (jSLE) presented with a life‐threatening and previously unreported triad: the simultaneous onset of acute pancreatitis, severe axonal polyneuropathy, and autoimmune Type 1 Diabetes (T1D ...
Laiba Hashmi, Fazeela Bibi, Kishan Chand Lohana, Khalil El Abdi, Zonaira Mushahid, Muhammad Asad Asif, Mahnoor Ilyas, Osvani Leyva Matos, Ariba Munam, Muhammad Saad Sammi, Samaha Kanden Mohammed Shafi, Said Hamid Sadat   +11 more
doaj   +3 more sources

Vitronectin, a Novel Urinary Proteomic Biomarker, Promotes Cell Pyroptosis in Juvenile Systemic Lupus Erythematosus

Mediators of Inflammation, 2022
Objective. Identifying new markers of juvenile systemic lupus erythematosus (JSLE) is critical event to predict patient stratification and prognosis. The aim of the present study is to analyze alteration of urinary protein expression and screen potential
Song Zhang, Wenxu Pan, Hongli Wang, Cheng Zhi, Yanhao Lin, Ping Wu, Qi Ren, Ping Wei, Rui Chen, Feng Li, Ying Xie, Chun Kwok Wong, Hong Tang, Zhe Cai, Wanfu Xu, Huasong Zeng   +15 more
doaj   +2 more sources

TNFSF4/OX40L and IKZF1/IKAROS Genetic Variant Associations with Egyptian Juvenile Systemic Lupus Erythematosus (JSLE) [PDF]

Biology
Background: The etiopathogenesis of juvenile systemic lupus erythematosus (JSLE), a complex and complicated illness, is unknown. Genetic, environmental, and dysregulated immune system responses are all thought to contribute to the disease’s etiology ...
Zeinab R. Attia, Ahmed M. Amshawee, Ahmed Flayyih Hasan, Dalia Tawfeek Hussein, Rania A. Abd El Azeem, Mohamed M. Zedan, Thuraya M. Mutawi, Nanis S. El-beltagy, Mohamed A. El Basuni   +8 more
doaj   +2 more sources

Interdisciplinary Clinical Practice Guidelines for patient-centred management of juvenile-onset systemic lupus erythematosus [PDF]

EULAR Rheumatology Open
: Objectives: To develop updated interdisciplinary clinical practice guidelines for the management of juvenile-onset systemic lupus erythematosus (jSLE) in a patient-centred, treat-to-target (T2T) approach.
Kirsten Mönkemöller, Lutz T. Weber, Martin Häusler, Tilmann Kallinich, Susanne Benseler, Hermine I. Brunner, Caroline Bieber, Jürgen Brunner, Christoph Deuter, Gabriele Hahn, Christian Hedrich, Claas Hinze, Anton Hospach, Heike-Katharina Hoyer-Kuhn, Ales Janda, Dirk Kamitz, Min Ae Lee-Kirsch, Ulrich Neudorf, Jörg Reichert, Martin Aringer, Sabine Schanze, Nicolaus Schwerk, Merle Seume, Fabian Speth, Norbert Wagner, Matthias Schneider, Burkhard Tönshoff, Klaus Tenbrock, Dieter Haffner, Catharina Schuetz   +29 more
doaj   +2 more sources

Interplay of NF-κB and PPAR-γ transcription factors in patients with juvenile systemic lupus erythematosus [PDF]

Lupus Science and Medicine
Objective Juvenile SLE (jSLE) is an autoimmune disease characterised by the presence of high levels of autoantibodies, predominantly targeting nuclear antigens, resulting in a breakdown of self-tolerance.
Ozgur Kasapcopur, Sezgin Sahin, Amra Adrovic, Kenan Barut, Sinem Durmus, Remise Gelisgen, Hafize Uzun   +6 more
doaj   +2 more sources

Endocrine and metabolic comorbidities in juvenile-onset systemic lupus erythematosus [PDF]

Frontiers in Medicine
Background and aimsJuvenile-onset systemic lupus erythematosus (JSLE) is a chronic autoimmune disease affecting individuals under 18, causing multi-system impairment.
Su Jin Park, Moon Bae Ahn, Dae Chul Jeong   +2 more
doaj   +2 more sources

Kidney Function, Age, and Education as Contributors to Depression and Anxiety in Juvenile Systemic Lupus Erythematosus

European Journal of Investigation in Health, Psychology and Education, 2021
Juvenile systemic lupus erythematosus (JSLE) is diagnosed in children younger than 18 years of age. Depression and anxiety are common, but not well understood in JSLE.
Margarida Figueiredo-Braga, Beatriz Silva, Sara Ganhão, Francisca Aguiar, Caleb Cornaby, Iva Brito, Brian D. Poole   +6 more
doaj   +1 more source

The role of hsa_circ_0008945 in juvenile-onset systemic lupus erythematosus

BMC Medical Genomics, 2023
Background circular RNAs (circRNAs) play a crucial role in many physiological and pathological processes including juvenile-onset systemic lupus erythematosus (JSLE).
Qifan Wang, Baiye Xu, Qingmei Zhang, Haidao Wang, Shulian Chen, Tingting Chen, Shishan Liang   +6 more
doaj   +1 more source

Systemic lupus erythematosus organ manifestation and disease activity in children based on Mexican systemic lupus erythematosus disease activity index score at East Java, Indonesia

Indian Journal of Rheumatology, 2021
Background: Disease activity in systemic lupus erythematosus (SLE) is associated with organ damage, outcome worsening, comorbidities, and mortalities in the patients.
Zahrah Hikmah, Anang Endaryanto, I Dewa Gede Ugrasena   +2 more
doaj   +1 more source