Results 171 to 180 of about 18,031 (200)

Ocular Manifestations in Children with Juvenile-Onset Systemic Lupus Erythematosus

Seminars in Ophthalmology, 2017
To study the ocular manifestations of juvenile systemic lupus erythematosus (JSLE), including the ocular side-effects of the systemic medications used.A descriptive cross-sectional study on 40 children diagnosed with JSLE was conducted. Ophthalmological and laboratory investigations as well as a calculation of the Systemic Lupus Disease Activity Index ...
Ghada, Gawdat, Dina, El-Fayoumi, Huda, Marzouk, Yomna, Farag   +3 more
openaire   +2 more sources

Validation of the systemic lupus erythematosus responder index for use in juvenile-onset systemic lupus erythematosus

Annals of the Rheumatic Diseases, 2014
This study tested the concurrent validity of the systemic lupus erythematosus responder index (SRI) in assessing improvement in juvenile-onset systemic lupus erythematosus (jSLE).The SRI considers changes in the SELENA-SLEDAI, BILAG and a 3-cm visual analogue scale of physician-rated disease activity (PGA) to determine patient improvement.
Mina R, Klein Gitelman MS, Nelson S, Eberhard BA, Higgins G, Singer NG, Onel K, Tucker L, O'Neil KM, Punaro M, Levy DM, Haines K, MARTINI, ALBERTO, Ruperto N, Lovell D, Brunner HI   +15 more
openaire   +4 more sources

Juvenile-onset systemic lupus erythematosus: different clinical and serological pattern than adult-onset systemic lupus erythematosus

Annals of the Rheumatic Diseases, 2009
To investigate differences in clinical signs and symptoms, and in antinuclear antibodies (ANA), between patients with juvenile-onset and adult-onset systemic lupus erythematosus (SLE).Clinical and serological data of 56 patients with juvenile-onset SLE were compared with data of 194 patients with adult-onset SLE. ANA were determined by line immunoassay
I E A, Hoffman, B R, Lauwerys, F, De Keyser, T W J, Huizinga, D, Isenberg, L, Cebecauer, J, Dehoorne, R, Joos, G, Hendrickx, F, Houssiau, D, Elewaut   +10 more
openaire   +2 more sources

Multi-disciplinary care in juvenile-onset systemic lupus erythematosus

British Journal of School Nursing, 2012
Juvenile onset systemic lupus erythematosus (JSLE) is a chronic autoimmune disease that can affect any part of the body including skin, joints and organs and can be associated with significant morbidity and mortality. Multi-disciplinary care of children and young people with JSLE is essential, in close partnership with schools.
Jane Kelly, Jane Dunnage, Michael W Beresford, Liza J McCann   +3 more
openaire   +1 more source

Analysis of serum IL-38 in juvenile-onset systemic lupus erythematosus

Modern Rheumatology, 2018
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with widespread immunologic abnormalities and multiple organ involvement [1].
Yusuke, Takeuchi, Tomoko, Seki, Norimoto, Kobayashi, Kenji, Sano, Tomonari, Shigemura, Hisashi, Shimojo, Kazuhiko, Matsumoto, Kazunaga, Agematsu   +7 more
openaire   +2 more sources

Herpes Zoster in Juvenile-Onset Systemic Lupus Erythematosus

The Pediatric Infectious Disease Journal, 2006
Herpes zoster (HZ) is common in systemic lupus erythematosus (SLE) patients, but its clinical features and risk factors in juvenile-onset SLE have not been well described before.A retrospective review of the clinical course and infections in pediatric SLE patients managed in our institution from 1988-2004 was performed.
HokKung Ho, M, Lau, YL, Lee, PPW, Lee, TL, Wong, WHS   +4 more
openaire   +5 more sources

Disease modifying immunosuppressant drugs for juvenile-onset systemic lupus erythematosus

Cochrane Database of Systematic Reviews, 2010
This is the protocol for a review and there is no abstract. The objectives are as follows: To summarise the evidence from randomised controlled trials for the effectiveness and safety of DMARDs in the treatment of juvenile-onset systemic lupus erythematosus, specifically: To quantify the effects of DMARDs on disease activity, health related ...
Craig, Jean V., Pain, Clare E., Beresford, Michael William   +2 more
openaire   +2 more sources

Juvenile-onset systemic lupus erythematosus: how to diagnose and manage

Paediatrics and Child Health, 2015
Abstract Systemic lupus erythematosus (SLE) is the prototypic autoimmune disorder, characterised by auto-antibody production against nuclear antigens. Juvenile-onset systemic lupus erythematosus (JSLE) is a more severe form than the adult-onset disease, with a more balanced gender ratio.
Louise Oni, Colin Thorbinson, Michael W. Beresford   +2 more
openaire   +1 more source

Renal biomarkers in Juvenile-onset systemic lupus erythematosus

2013
Background: Juvenile-onset Systemic Lupus Erythematosus (JSLE) is a rare, but severe, autoimmune condition with lupus nephritis (LN) occurring in up to 80% of patients and predisposing to an increased mortality. Aims/Objectives: As part of the UK JSLE Cohort Study this study aimed to identify whether standard and/or novel biomarkers are useful for ...
openaire   +1 more source

Juvenile onset systemic lupus erythematosus thyroid dysfunction: A subgroup with mild disease?

Journal of Autoimmunity, 2009
The aim of this study was to evaluate the frequency of thyroid dysfunction and thyroid antibodies in patients with juvenile onset Systemic Lupus Erythematosus (JOSLE) and its association with clinical and immunological features. Seventy-seven patients with JOSLE, 64 females, median age 19 years, were consecutively enrolled from March to December 2007 ...
Luciana, Parente Costa, Eloisa, Bonfá, Ciro D, Martinago, Ricardo M, de Oliveira, Jozélio Freire, Carvalho, Rosa M R, Pereira   +5 more
openaire   +2 more sources