Results 51 to 60 of about 530,157 (260)
Ten‐Year Post‐traumatic Osteoarthritis Incidence Is Low After Pediatric Isolated Meniscal Surgery but Lower After Meniscal Repair Than Meniscectomy
Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.Purpose
To examine the 5‐ and 10‐year incidence of post‐traumatic osteoarthritis (PTOA) after isolated, primary meniscal surgery differentiating between meniscal repair and meniscectomy, in pediatric patients. Methods
Pediatric patients (≤16 years) undergoing primary meniscectomy or meniscal repair (2010‐2023) with ≥5‐year follow‐up were identified in ...Annika N. Hiredesai, Alejandro M. Holle, Jay R. Patel, Katelyn T. Koschmeder, Sailesh V. Tummala, Jeffrey M. Vaughn, Karan A. Patel +6 morewiley +1 more sourceArthritis and disability [PDF]
, 2014 Executive summary: Arthritis Australia commissioned the Social Policy Research Centre (SPRC) at UNSW Australia to carry out research on the lived experience of people with arthritis related conditions.Shona Bates, Karen Fisher, Fisher, KR ; https://orcid.org/, Bates, S ; https://orcid.org/, Smedley, C, Wong, M ; https://orcid.org/, Melissa Wong, Rosemary Kayess, Charlotte Smedley, Kayess, R +9 morecore +2 more sourcesFrom Interferon Signature to the Clinical Landscape: Type I Interferonopathies
Arthritis &Rheumatology, EarlyView.Objective
TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan +13 morewiley +1 more sourceDefining criteria for disease activity states in systemic juvenile idiopathic arthritis based on the systemic Juvenile Arthritis Disease Activity Score [PDF]
Objective
To develop and validate cutoff values in the systemic Juvenile Arthritis Disease Activity Score 10 (sJADAS10) that distinguish the states of inactive disease (ID), minimal disease activity (MiDA), moderate disease activity (MoDA), and high ...Robasto, Francesca, Silva, Rodrigo M., Shalaby, Radwa H., Consolaro, A., Marrani, Edoardo, Villarreal, Giselle, Lotfy, Hala M., Ozen, S., Costi, Stefania, Kriulin, Ivan, Sztajnbok, Flavio, Al‐Mayouf, Sulaiman M., Abu-Zaid, M., Abu‐Rumeleih, S., Hassan, Waleed, Maggio, Maria C., Minoia, F., Civino, Adele, Montin, Davide, Tarantola, Letizia, Khubchandani, Raju, Fouad, Nermeen A., Osman, Naglaa S., Vilaiyuk, Soamarat, Filocamo, Giovanni, Pal, P., Maldar, Naziya P., Almaaitah, Hiba, Al‐Sofyani, Fuad, Bracaglia, C., El Owaidy, R., El Miedany, Yasser, Alzyoud, Raed, Pardeo, M., Khan, A., Mahgoub, Marwa Y., Patrone, Elisa, Bathia, Jigna N., Saad‐Magalhães, Claudia, Eissa, M., Lerkvaleekul, Butsabong, Simonini, Gabriele, De Benedetti, F., Katsicas, María M., Ravelli, A., Rebollo‐Gimenez, Ana I., Mosa, D., Bayindir, Yagmur, Licciardi, F., Abu‐Shady, Hend, Vyzhga, Y., Radwan, Ahmed R., Alexeeva, Ekaterina, Dvoryakovskaya, Tatyana, Marino, Achille, Nasef, S., Kostik, M., Dāvidsone, Zane, Pistorio, Angela, Adel, Yasmin, Diomeda, Federico, Alsuweiti, Motasem, Rosina, Silvia, Tabra, Samar A. A., Rossano, Martina, El‐Ghoneimy, Dalia H., Mohamed, Sheren E. M., Belozerov, Konstantin E., Abu-Shady, Hend, De Benedetti, Fabrizio, Maggio, Maria C, Maldar, Naziya P, Abu‐Rumeileh, Sarah, Eissa, Mervat, Tabra, Samar A A, Mosa, Doaa M, Mohamed, Sheren E M, Belozerov, Konstantin E, Al-Sofyani, Fuad, Lotfy, Hala M, Abu‐Zaid, Mohamed H., Bathia, Jigna N, Saad-Magalhães, Claudia [UNESP], Rebollo-Giménez, Ana I, Kostik, Mikhail M, Katsicas, María M, El Owaidy, Rasha, Vyzhga, Yulia, Radwan, Ahmed R, Saad-Magalhães, Claudia, Osman, Naglaa S, Ozen, Seza, Abu-Rumeileh, Sarah, Kostik, Mikhail M., El-Ghoneimy, Dalia H, Nasef, Samah I, Pardeo, Manuela, Bracaglia, Claudia, Rebollo-Gimenez, Ana I., Silva, Rodrigo M, Al-Mayouf, Sulaiman M, Khan, Archana, Mosa, Doaa M., Pal, Priyankar, Licciardi, Francesco, Al-Mayouf, Sulaiman M., Consolaro, Alessandro, Abu-Rumeleih, Sarah, Abu-Zaid, Mohamed H., Fouad, Nermeen A, Abu-Zaid, Mohamed H, Shalaby, Radwa H, El-Ghoneimy, Dalia H., Mahgoub, Marwa Y, Nasef, Samah I., Ravelli, Angelo, Minoia, Francesca +116 morecore +1 more sourcePharmacokinetics, Effectiveness and Safety of Certolizumab Pegol in Children and Adolescents With Active Juvenile Idiopathic Arthritis: 9+‐Year Results From a Multicenter, Open‐Label Study
Arthritis &Rheumatology, EarlyView.Objective
The purpose of this study was to assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods
Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients aged 2 to 17 years with ...Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Laura Shaughnessy, Saori Shimizu, Paulette Williams, Rocío Lledó‐García, Gauri Utturkar, Baran Ufuktepe, Alberto Martini, Daniel J. Lovell, Nicolino Ruperto, the Paediatric Rheumatology International Trials Organisation (PRINTO); the Pediatric Rheumatology Collaborative Study Group (PRCSG), Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Alberto Martini, Daniel L. Lovell, Nicolino Ruperto +52 morewiley +1 more sourceComplement Activation Linked to Type II Interferon Signaling in Still Disease
Arthritis &Rheumatology, EarlyView.Objective
Still disease (SD) is an autoinflammatory syndrome characterized by innate immune dysregulation. Although complement can drive inflammation, its involvement in SD remains to be defined. Thus, we aimed to assess complement activation in SD. Methods
Complement was assessed using transcriptomic, proteomic, and in vitro approaches. RNA sequencing Freya M. C. H. Huijsmans, Tabea Thalheim, Alejandra Bodelón, Greta Rogani, Lyanne J. P. M. Sijbers, Remco G. A. Erkens, Aafke de Ligt, Rianne Scholman, Aron Brinker, Gisella B. Beretta, Nienke M. Ter Haar, Thomas Vogl, Johannes Roth, Trang T. Duong, Sytze de Roock, Joost F. Swart, Deborah A. Marshall, Susanne M. Benseler, Rae S. M. Yeung, Christoph Kessel, Sebastiaan J. Vastert, Emely L. Verweyen, Jorg van Loosdregt, on behalf of the UCAN CAN‐DU/UCAN CURE Consortia and the One Child Every Child Initiative, Adam Huber, Bianca Lang, Chelsea DeCoste, Elizabeth Stringer, Suzanne Ramsey, Alan Rosenberg, Kate Neufeld, Mehul Jariwala, Tristan Kerr, Alexander Mosoiu, Alisa Rachlis, Amy Xu, Arthur Cheng, Brenleigh Jebb, Brian Feldman, Bruno Pereira, Deborah Levy, Dilan Dissanayake, Elizaveta Limenis, Evelyn Rozenblyum, Harper Cheng, Jennifer Ji Young Lee, Lynn Spiegel, Rayfel Schneider, Ronald Laxer, Ruud Verstegen, Shirley Tse, Andrea Human, David Cabral, Herman Tam, Jaime Guzman, Kim Morishita, Kristin Houghton, Lori Tucker, Mercedes Chan, Ross Petty, Tommy Gerschman, Annet van Royen‐Kerkhof, Berent Prakken, Erika Van Nieuwenhove, Marc Jansen, Nico Wulffraat, Ciarán Duffy, Nadia Luca, Roman Jurencak, Tala El Tal, Claire LeBlanc, Gaëlle Chédeville, Piya Lahiry, Rosie Scuccimarri, Sarah Campillo, Clare Hutchinson, Daniah Basodan, Dax G Rumsey, Hon Yan Ng, Jeanine McColl, Lillian Lim, Tara McGrath, Danielle Brinkman, Petra Hissink Muller, Elizabeth Legger, Wineke Armbrust, Ellen Schatorje, Esther Hoppenreijs, Elodie Boudes, Gillian Currie, Heinrike Schmeling, Muhammed Dhalla, Nicole Johnson, Paivi Miettunen, Ravneet Sran, Rebeka Stevenson, Erkan Demirkaya, Jonathan Park, Roberta Berard, Giske Biesbroek, Mariken Gruppen, Gordon Soon, Joseph Cafazzo, Liane Heale, Michelle Batthish, Tania Cellucci, Lily Lim, Maarten IJzerman, Marinka Twilt, Marleen Verkaaik, Philomine van Pelt, Sylvia Kamphuis, Michelle Kip, Nicholas Blanchette, Paul Dancey, Regina de Geus +115 morewiley +1 more source