Results 51 to 60 of about 41,818 (235)

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Burden of childhood-onset arthritis

Pediatric Rheumatology Online Journal, 2010
Juvenile arthritis comprises a variety of chronic inflammatory diseases causing erosive arthritis in children, often progressing to disability. These children experience functional impairment due to joint and back pain, heel pain, swelling of joints and ...
Hassett Afton L, Peterson Margaret GE, Moorthy Lakshmi N, Lehman Thomas JA   +3 more
doaj   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Ten‐Year Public Expenditure Savings Associated with TNF Inhibitor Biosimilars under Australia's Pharmaceutical Benefits Scheme

Clinical Pharmacology &Therapeutics, EarlyView.
Biologic therapies are a major and growing driver of pharmaceutical expenditure globally, with tumor necrosis factor (TNF) inhibitors among the most widely used and costly biologics. In Australia, these therapies are funded through the Pharmaceutical Benefits Scheme (PBS), where biosimilars offer lower cost alternatives; however, the long‐term public ...
Chin Hang Yiu, Bella D. Ianni, Richard O. Day, Jacques Raubenheimer, Christine Y. Lu   +4 more
wiley   +1 more source

Tocilizumab in the treatment of systemic juvenile idiopathic arthritis

Open Access Rheumatology: Research and Reviews, 2012
Miho Murakami,1 Minako Tomiita,2,3 Norihiro Nishimoto11Laboratory of Immune Regulation, Wakayama Medical University, Wakayama, 2Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, 3Department of Allergy and Rheumatology, Chiba
Murakami M, Tomiita M, Nishimoto N
doaj  

THE ROLE OF APOPTOSIS VIOLATIONS IN THE JUVENILE IDIOPATHIC ARTHRITIS FORMATION

Педиатрическая фармакология, 2012
We investigated the polymorphism of the gene p53 exon 4 Arg72Pro and intron 3 ins/del 16 b. p. in children with juvenile idiopathic arthritis in order to identify the influence of gene polymorphisms on the course and outcome of the disease.
A. N. Kozhevnikov, M. V. Moskalenko, N. A. Pozdeeva, G. A. Novik, V. I. Larionova   +4 more
doaj   +1 more source

Piezosurgical partial ostectomy of the incisive bone for an ossifying fibroma removal in a 4‐year‐old Warmblood gelding

Equine Veterinary Journal, EarlyView.
Abstract Background Ossifying fibromas are uncommon in horses and complete surgical excision with premaxillectomy, maxillectomy or mandibulectomy is recommended. Piezosurgery has been previously used in equines only in one study. Objective To report a case of ossifying fibroma treated with piezosurgery and to describe its follow‐up.
G. Forni, M. E. Falomo, I. Casalini, M. Isola   +3 more
wiley   +1 more source

Frequency and diagnostic significance of anti-cyclic citrullinated peptide antibodies (ACCP) and anti-modified citrullinated vimentin antibodies (AMCV) in children with early juvenile arthritis

Научно-практическая ревматология, 2008
Objective. To determine frequency of anti-cyclic citrullinated peptide antibodies (ACCP) and anti-modified citrullinated vimentin antibodies (AMCV) elevation and their diagnostic significance in children with early juvenile arthritis (JA).
S O Salugina, E S Fedorov, E N Alexandrova, A A Novikov, A A Baranov, Y A Valogina, M. V. Cherkasova, T N Nikolaeva, N A Subova   +8 more
doaj   +1 more source

Association of Childhood Acute Leukemia With Autoimmune Diseases

International Journal of Cancer, EarlyView.
A possible link exists between various pediatric autoimmune diseases (AIDs) and increased risk of childhood leukemia. Although immune dysregulation is a key feature of these conditions, the connection between them remains unclear. In this study, using cancer registry data in Finland, the authors examined associations between AIDs and childhood acute ...
Ida Pellikka, Julia Ventelä, Anssi Auvinen, Olli Lohi, Atte Nikkilä   +4 more
wiley   +1 more source

Modern concepts of vitamin D role in juvenile idiopathic arthritis in children (review)

Zdorovʹe Rebenka, 2019
Arthritis is one of the most common chronic rheumatic diseases in children. Juvenile idiopathic arthritis (JIA) is the current nomenclature that is used to refer to a group of diseases that include chronic arthritis, childhood-onset arthritis of unknown ...
Y.V. Khadzhynova
doaj   +1 more source