Journal of Pediatric Gastroenterology and Nutrition, EarlyView.Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Dan Turner +21 more
wiley +1 more source
Vital activity limitation in patients with juvenile chronic arthritis
Современная ревматология, 2012 The results of examination using the CHAQ are employed to analyze the degree of vital activity limitation in patients with different types of juvenile chronic arthritis. Whether it is advisable to use the questionnaire in young preschoolers is discussed.
Tatyana Andreyevna Shelepina
doaj +3 more sources
FRI0374 PLASMA LEVELS OF 14-3-3 PROTEIN, S100A8/S100A9-PROTEIN, INTERLEUKIN-6, INTERLEUKIN-18, INTERLEUKIN-4, INTERLEUKIN-17, INTERLEUKIN-1Β AND TUMOR NECROSIS FACTOR-Α IN CHRONIC NON-BACTERIAL OSTEOMYEILITIS AND NON-SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS [PDF]
, 2020 Mikhail M. Kostik +7 more
openalex +1 more source
Juvenile idiopathic arthritis-associated uveitis [PDF]
, 2016 Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease of childhood, with JIA-associated uveitis its most common extra-articular manifestation.
Clarke, Sarah +2 more
core +3 more sources
JPGN Reports, EarlyView.Abstract Objective To determine if multiplex autoantibody arrays can identify novel biomarker signatures in children with one or multiple autoimmune diseases (polyautoimmunity). Methods Plasma collected from children (18 years or younger) in the Boston Children's Hospital Precision Link Biobank for Health Discovery between January 2007 and June 2021 ...
Nan Du +7 more
wiley +1 more source
Social Functioning of Children and Their Parents: Are They Related? [PDF]
, 2010 This study examined whether parents' social support was related to their children's peer acceptance and likability. The moderating role of the parent's and the child's gender was also examined.
Wetzel, Megan
core
Mydriasis as a Secondary Effect in Patients With HLA‐B27–Associated Uveitis
Medicine Advances, EarlyView.HLA‐B27‐associated acute anterior uveitis causes significant inflammation of the iris and anterior chamber, which disrupts normal parasympathetic control and results in increased sympathetic tone leading to pupil dilation (mydriasis). This finding can sometimes resemble herpetic uveitis, making a clinical context and careful evaluation crucial for ...
Saim Mahmood Khan +6 more
wiley +1 more source
Interleukin-7 deficiency in rheumatoid arthritis: consequences for therapy-induced lymphopenia [PDF]
, 2004 We previously demonstrated prolonged, profound CD4+ T-lymphopenia in rheumatoid arthritis (RA) patients following lymphocyte-depleting therapy. Poor reconstitution could result either from reduced de novo T-cell production through the thymus or from poor
Bingham, S.J. +26 more
core +2 more sources
New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics
Rare Metals, EarlyView.ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu +8 more
wiley +1 more source
Cardiac tamponade in juvenile chronic arthritis: report of two cases and review of publications. [PDF]
, 1990 J Goldenberg +6 more
openalex +1 more source