Results 141 to 150 of about 149,638 (356)

The return of metabolism: biochemistry and physiology of glycolysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning   +19 more
wiley   +1 more source

How Do Dental Professionals and Students Assess Orthodontic Case Complexity?

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Background Accurately diagnosing and assessing orthodontic case complexity is essential for treatment planning, estimating therapy duration, and determining required expertise. Various indices, such as the American Board of Orthodontics Discrepancy Index (ABO DI), provide objective evaluations.
Giulia Semerari   +4 more
wiley   +1 more source

Serum interleukin 12 concentration in juvenile chronic arthritis [PDF]

open access: bronze, 1998
Marco Gattorno   +5 more
openalex   +1 more source

Catalyzing collective action in evidence‐based parenting support: A model for effective research alliances

open access: yesFamily Relations, EarlyView.
Abstract Objective The purpose of this article was to present a model for effective research alliances that facilitate collective action to advance scientific fields. The Parenting and Family Research Alliance (PAFRA) was used as an exemplar to illustrate its application.
Matthew R. Sanders   +13 more
wiley   +1 more source

A Retrospective Study of Adult and Pediatric D‐Dimer Tests to Identify Opportunities for Improved Utilization

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction D‐dimers are produced by lysis of cross‐linked fibrin. In children, D‐dimer testing is used to evaluate disseminated intravascular coagulation (DIC) and some inflammatory states, but its use is not validated for screening or ruling out suspected venous thromboembolic events (VTE).
Rabab Al Dawood   +4 more
wiley   +1 more source

DNA methylation profiling of human CD4+ T helper cells reveals the epigenetic control of SLAMF7 expression in IFN‐γ producing cells

open access: yesImmunology &Cell Biology, EarlyView.
In this study, we confirmed the close relationship between Th17 and ncTh1 cells by conducting a genome‐wide DNA methylation analysis with CD4+ T helper subsets. However, partial epigenetic changes enable ncTh1 cells to execute Th1‐specific transcriptional programs and express proteins such as SLAMF7. Therefore, we hypothesize that epigenetic adaptation
Anna Ntalli   +7 more
wiley   +1 more source

Epidemiology and Genetics of Rheumatic Diseases Suggest a Constant Rate of DNA Damage as Underlying Cause

open access: yesImmunology, EarlyView.
A constant rate of DNA damage that is not perfectly repaired will cause a constant rate of DNA mutations. The chance of mutation will increase if DNA is prone to damage, such as occurs in somatic hypermutation (SHM) hotspots and GC‐rich DNA. Thus, if one mutation‐prone DNA site drives disease, the age of onset of disease and degree of penetrance should
Piet C. de Groen
wiley   +1 more source

Periodontitis and Periodontal Conditions in Systemically Healthy Children and Adolescents

open access: yesJournal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To answer the PICoS question ‘in systemically healthy children and adolescents (Population), what are the main features of periodontitis, necrotising periodontal diseases (NPD) and other periodontal conditions (periodontal abscesses, endo‐periodontal lesions, traumatic occlusal forces, prosthesis‐ and tooth‐related factors ...
Inbar Eshkol‐Yogev   +5 more
wiley   +1 more source

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