Results 71 to 80 of about 149,638 (356)

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Optimising use of electronic health records to describe the presentation of rheumatoid arthritis in primary care: a strategy for developing code lists [PDF]

, 2013
Background Research using electronic health records (EHRs) relies heavily on coded clinical data. Due to variation in coding practices, it can be difficult to aggregate the codes for a condition in order to define cases.
A Hansell, A. Rosemary Tate, Amanda Nicholson, AR Tate, AR Tate, Christian Lovis, CJ Edwards, CJ Edwards, D Blumenthal, D Blumenthal, DA Houssien, DG Manuel, DH Lawson, E Herrett, Elizabeth Ford, Greta Rait, Helen E. Smith, IE van der Horst-Bruinsma, Irene Petersen, JA Cassell, JA Linder, Jackie Cassell, K Jordan, K Jordan, K Jordan, K Kumar, K Thiru, Kevin A. Davies, KP Liao, MC Gulliford, MG Marmot, RJ Carroll, S Dave, S DeLisle, SL Thomas, SS Pakhomov, SW Pascoe, U Arndt   +37 more
core   +10 more sources

The Molecular Genetic Features of Patients with Juvenile Arthritis in Yakutia [PDF]

International Journal of Biomedicine, 2019
The research objective was to conduct a retrospective study of patients with Juvenile arthritis (JA) in association with the carriage of the HLA-B27 allele.
Khariton A. Kurtanov, ¹; Fekla V. Vinokurova, Nadezhda I. Pavlova, Aitalina S. Golderova, Aleksandra T. Diakonova, Galina A. Apsolikhova, Vlad A. Alekseev   +6 more
doaj   +1 more source

Performance Characteristics of Anti‐Collagen II Antibodies in Relapsing Polychondritis and Related Diseases: Prospective Analysis, Systematic Review, and Meta‐Analysis

Arthritis Care &Research, Accepted Article.
Background Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti‐collagen II (anti‐Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick, Marcela A. Ferrada, Alice Fike, Kaitlin A. Quinn, Benjamin A. Turturice, Casey Stein, Peter C Grayson   +6 more
wiley   +1 more source

Systemic juvenile idiopathic arthritis with chronic recurrent multifocal osteomyelitis in an adolescent: A case report

SAGE Open Medical Case Reports
Chronic recurrent multifocal osteomyelitis is a rare auto-inflammatory disease in children, with only a few reports of its association with other inflammatory diseases, such as systemic juvenile idiopathic arthritis. A 15-year-old boy was admitted due to
Mohsen Jari, Sogol Alesaeidi
doaj   +1 more source

Childhood Leukemia Presenting as Clinical Arthritis and Chronic Recurrent Multifocal Osteomyelitis: A Case Report

Oman Medical Journal
A previously healthy five-year-old boy was seen in the rheumatology clinic with a five-month history of migrating joint discomfort, followed by right knee and left ankle arthritis. He showed no signs of lymphadenopathy, organomegaly, rashes, or fever. He
Eman Al Masroori, Sumaiya Al Hadhrami, Nawal Al Shamli   +2 more
doaj   +1 more source

СONCENTRATION OF ANTI-INFLAMATORY CYTOKINES IN CELL CULTURE SUPERNATANTS IN CHILDREN WITH JUVENILE IDIOPATHIC ARTHRITIS

Медицинская иммунология, 2019
Juvenile idiopathic arthritis is a chronic inflammatory disease of the joints in children, mainly of autoimmune or auto-inflammatory nature. It is a heterogeneous group, which includes different subtypes of the disease. Different mechanisms may play role
I. M. Krivolapova, I. A. Pashnina, V. A. Chereshnev   +2 more
doaj   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) network investigators   +14 more
wiley   +1 more source

Demographic, clinical, and treatment characteristics of the juvenile primary fibromyalgia syndrome cohort enrolled in the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry. [PDF]

, 2019
BackgroundTo describe the demographic, clinical, and treatment characteristics of youth diagnosed with juvenile primary fibromyalgia syndrome (JPFS) who are seen in pediatric rheumatology clinics.MethodsInformation on demographics, symptoms, functioning,
Boneparth, Alexis D, CARRA Registry Investigators, Connelly, Mark, Schikler, Kenneth N, Weiss, Jennifer E   +4 more
core   +1 more source

Oral Health Status among Group of Patients with Juvenile Idiopathic Arthritis According to Duration of Illness and Age Group in Iraq

Journal of Baghdad College of Dentistry, 2016
Background: Juvenile idiopathic arthritis (JIA) is a chronic disease of childhood. Increased prevalence of periodontal disease and dental caries in juvenile idiopathic arthritis is due to difficulties in executing good oral hygiene.
Zainab Shallan, Nadia Aftan Al-Rawi
doaj   +1 more source