Results 91 to 100 of about 378,540 (249)

Diagnostic utility of inflammatory markers in formalin‐fixed and paraffin‐embedded muscle biopsies for idiopathic inflammatory myopathies

open access: yesHistopathology, EarlyView.
Formalin‐fixed, paraffin‐embedded (FFPE) muscle tissue supports robust immunohistochemical detection of MHC II, MxA, and p62 with performance comparable to frozen sections. This approach reliably identifies the pathological signatures of inclusion body myositis, dermatomyositis, immune‐mediated necrotizing myopathy, and overlap myositis, enhancing the ...
Chinnawut Suriyonplengsaeng   +1 more
wiley   +1 more source

Panniculitis, A Rare Presentation of Onset and Exacerbation of Juvenile Dermatomyositis: A Case Report and Literature Review

open access: yesThe Turkish Journal of Gastroenterology, 2018
Panniculitis occurring in juvenile dermatomyositis has been rarely reported. However, it may lead to poor quality of life, and furthermore, induce an irreversible structural change in the subcutaneous layer.
Yun Jung CHOI, Wan-hee YOO
doaj  

Macrophage activation syndrome due to juvenile amyopathic dermatomyositis with atypical onset

open access: yesTurkderm Turkish Archives of Dermatology and Venereology, 2022
Macrophage activation syndrome (MAS) is a life-threatening condition associated with rheumatic diseases. It is rarely reported in juvenile dermatomyositis.
Esma İnan Yüksel   +3 more
doaj   +1 more source

Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models

open access: yesArthritis &Rheumatology, Volume 78, Issue 9, Page 1942-1951, September 2026.
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis   +11 more
wiley   +1 more source

Superimposed segmental manifestation of juvenile amyopathic dermatomyositis in a 9-year-old boy

open access: yesIndian Journal of Dermatology, 2017
Dermatomyositis is a well-known autoimmune disorder. On the other hand, juvenile amyopathic dermatomyositis (JADM) occurs rather rarely. Here, we report an unusual case in a 9-year-old Turkish boy showing a unilateral linear inflammatory skin lesion that
Isil Bulur   +4 more
doaj   +1 more source

Association of Childhood Acute Leukemia With Autoimmune Diseases

open access: yesInternational Journal of Cancer, Volume 159, Issue 5, Page 1188-1195, 1 September 2026.
A possible link exists between various pediatric autoimmune diseases (AIDs) and increased risk of childhood leukemia. Although immune dysregulation is a key feature of these conditions, the connection between them remains unclear. In this study, using cancer registry data in Finland, the authors examined associations between AIDs and childhood acute ...
Ida Pellikka   +4 more
wiley   +1 more source

Unilateral Heliotrope Rash in Juvenile Dermatomyositis: An Unusual Presentation of an Underlying Serious Disease

open access: yesCase Reports in Rheumatology, 2014
Background. Heliotrope rash is one of the characteristic skin manifestations of juvenile dermatomyositis. It is a reddish-purple rash on the upper eyelids that is usually bilateral. Case Presentation.
Ghada Al-Janobi   +2 more
doaj   +1 more source

International Guideline on the Diagnosis and Management of Pediatric Patients With Hereditary Angioedema

open access: yesAllergy, Volume 81, Issue 8, Page 2744-2774, August 2026.
ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas   +128 more
wiley   +1 more source

Radiographic Patterns of Soft Tissue Calcinosis in Juvenile Dermatomyositis and its Clinical Implications [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2014
Juvenile Dermatomyositis (JDM) is a rare autoimmune inflammatory disease of muscles affecting children and adolescents with soft tissue calcification and varying systemic involvement.
SHANTIRANJAN SANYAL   +3 more
doaj   +1 more source

The Swedish National Pediatric Cataract Register (PECARE): Coexisting systemic disorders 2007–2023

open access: yesActa Ophthalmologica, Volume 104, Issue 5, Page 510-516, August 2026.
Abstract Purpose To analyse the frequency and type of coexisting systemic disorders in children operated on for cataract in Sweden. Methods Data were retrieved from the Swedish National Pediatric Cataract Register (PECARE) for children operated between January 1, 2007, and December 31, 2023 (n = 975), including follow‐ups at age 1, 2, 5 and 10 ...
David Wackerberg   +9 more
wiley   +1 more source

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