Results 71 to 80 of about 378,540 (249)

Favorable outcomes with reduced steroid use in juvenile dermatomyositis

Pediatric Rheumatology Online Journal, 2021
Background High-intensity glucocorticoid regimens are commonly used to induce and maintain remission in Juvenile Dermatomyositis but are associated with several adverse side-effects.
Amir B. Orandi, Lampros Fotis, Jamie Lai, Hallie Morris, Andrew J. White, Anthony R. French, Kevin W. Baszis   +6 more
doaj   +1 more source

Onset and Relapse of Juvenile Dermatomyositis Following Asymptomatic SARS-CoV-2 Infection

Journal of Clinical Immunology, 2021
Dear Editor, SARS-CoV-2 infection drives a marked inflammation and has been described to precede the appearance in rare occasion of various autoimmune and inflammatory diseases including clinical, radiological, muscle biopsy, and serological features ...
M. Rodero, S. Pelleau, A. Welfringer-Morin, D. Duffy, I. Melki, B. Bader-Meunier, V. Bondet, C. Gitiaux, J. Bonigen, Antoine Fayand, Laurence Courdavault Vagh Weinmann, E. Mahé, J. Charuel, M. Alyanakian, J. Herbeuval, M. White   +15 more
semanticscholar   +1 more source

Clues to Disease Activity in Juvenile Dermatomyositis: Neopterin and Other Biomarkers

Diagnostics, 2021
Easily accessible biomarkers are urgently needed to evaluate immune activation in Juvenile Dermatomyositis (JDM). The goal of this retrospective study is to define immunological and clinical differences between untreated JDM patients with either normal ...
Amer M. Khojah, Gabrielle A Morgan, L. Pachman   +2 more
semanticscholar   +1 more source

Juvenile amyopathic dermatomyositis

Dermatology Online Journal, 2005
A 3-year-old girl presented with a 6-month history of multiple, light-pink, flat-topped papules over the dorsal aspects of the metacarpophalangeal and interphalangeal joints of the hands and feet. Nailfold telangiectases, ragged cuticles, and a heliotrope color of the upper eyelids were also evident, but there was no clinical evidence of muscle ...
Henning, J Scott, Witkiewicz, Agnieszka, Schaffer, Julie V, Orlow, Seth J   +3 more
openaire   +4 more sources

Comparison between treatment naive juvenile and adult dermatomyositis muscle biopsies: difference of inflammatory cells phenotyping

Advances in Rheumatology, 2018
Background Different inflammatory cells (i.e., CD4, CD8, CD20 and CD68) are involved in pathogenesis of DM muscle. In this context, the aim of this study was to assess and compare these inflammatory cell phenotyping in muscle samples of treatment naive ...
Samuel Katsuyuki Shinjo, Adriana Maluf Elias Sallum, Sueli Mieko Oba-Shinjo, Marilda Guimarães Silva, Clovis Artur Silva, Suely Kazue Nagahashi Marie   +5 more
doaj   +1 more source

Respiratory symptoms as initial manifestations of interstitial lung disease in clinically amyopathic juvenile dermatomyositis: a case report with literature review

BMC Pediatrics, 2021
Background Clinically amyopathic juvenile dermatomyositis (CAJDM) is a clinical subgroup of juvenile dermatomyositis (JDM), characterized by JDM rashes with little or no clinically evident muscle weakness.
Jingyi Xia, Gaoli Jiang, Tingting Jin, Quanli Shen, Yangyang Ma, Libo Wang, Liling Qian   +6 more
doaj   +1 more source

Assessment of the trophological status of children with rheumatic diseases

Zdorovʹe Rebenka, 2021
Background. Analyzing modern medical literature, it can be noted that in pediatric rheumatology, insufficient attention is paid to assessing the trophological status of sick children.
L.I. Omelchenko, O.M. Mukvich, E.A. Belskaya, I.V. Dudka, T.A. Ludvik   +4 more
doaj   +1 more source

The Significance of Autoantibodies in Juvenile Dermatomyositis

BioMed Research International, 2021
Juvenile dermatomyositis is a chronic and rare autoimmune disorder classified into the spectrum of idiopathic inflammatory myopathies. Although this entity is mainly characterized by the presence of pathognomonic cutaneous lesions and proximal muscle ...
D. Kwiatkowska, A. Reich
semanticscholar   +1 more source

Interferon type I signature associated with skin disease in juvenile dermatomyositis

Frontiers in Medicine
Background Interferon type I (IFN-I) signaling system hyperactivation plays an important role in the pathogenesis of juvenile dermatomyositis (JDM). Aim of the study To analyze IFN-I score with disease activity in patients with JDM. Materials and methods
R. Raupov, E. Suspitsin, E. V. Preobrazhenskaya, M. Kostik   +3 more
semanticscholar   +1 more source

Clinical characteristics and concordance of anti‐MDA5 autoantibodies: A multicentre Australian study

Arthritis Care &Research, Accepted Article.
Objectives In Australia, anti‐MDA5 antibodies are exclusively tested by line immunoblot assay (LIA). The clinical concordance of a LIA‐positive anti‐MDA5 result is unclear. We aimed to describe the clinical features and determine the clinical concordance of patients with anti‐MDA5 antibodies.
Syed B Ali, Thomas Khoo, Keeran Shivakumar, Adam Caroll, Lauren Hender, Dimitra Beroukas, Kim Griggs, Celina Jin, Theo De Malmanche, Jessica Day, Gabor Major, Vidya Limaye   +11 more
wiley   +1 more source