Results 51 to 60 of about 378,540 (249)

Developmentally appropriate transitional care during the Covid-19 pandemic for young people with juvenile-onset rheumatic and musculoskeletal diseases: the rationale for a position statement

Pediatric Rheumatology Online Journal, 2021
Background The importance of developmentally appropriate transitional care in young people with juvenile-onset rheumatic and musculoskeletal disease is well recognised.
Janet E. McDonagh, Rachel Tattersall, Jacqui Clinch, Joanne Swan, Helen E. Foster, Liza McCann   +5 more
doaj   +1 more source

Juvenile Dermatomyositis: New Clues to Diagnosis and Therapy

Current Treatment Options in Rheumatology, 2021
To identify clues to disease activity and discuss therapy options. The diagnostic evaluation includes documenting symmetrical proximal muscle damage by exam and MRI, as well as elevated muscle enzymes—aldolase, creatine phosphokinase, LDH, and SGOT—which
L. Pachman, B. Nolan, Deidre DeRanieri, Amer M. Khojah   +3 more
semanticscholar   +1 more source

A Cause of High Creatine Kinase: A Case of Juvenile Dermatomyositis

Haseki Tıp Bülteni, 2014
Although juvenile dermatomyositis is rare, it is the most common idiopathic nonsupurrative inflammatory myositis in childhood. Skin lesions, proximal muscle weakness, elevated levels of muscle enzymes, electromyography, and muscle biopsy findings are ...
İsmail Yıldız, Özge Umur, Muhammet Ali Varkal, Alev Yılmaz, Gökçen Gündoğdu, Ayşe Kılıç, Fatma Oğuz, Emin Ünüvar   +7 more
doaj   +1 more source

Short-term effectiveness of baricitinib in children with refractory and/or severe juvenile dermatomyositis

Frontiers in Pediatrics, 2022
Objective To determine the short-term effectiveness safety of baricitinib in children with refractory and/or severe juvenile dermatomyositis (rsJDM) in a real-world setting. Methods This was a single-center retrospective study, including 20 children with
Zhaoling Wang, Qi Zheng, Wenjie Xuan, Xisheng Xu, Meiping Lu, Jianqiang Wu, Lixia Zou, Yiping Xu, Xuefeng Xu   +8 more
semanticscholar   +1 more source

Skeletal muscle major histocompatibility complex class I and II expression differences in adult and juvenile dermatomyositis

Clinics, 2012
OBJECTIVE: To analyze major histocompatibility complex expression in the muscle fibers of juvenile and adult dermatomyositis. METHOD: In total, 28 untreated adult dermatomyositis patients, 28 juvenile dermatomyositis patients (Bohan and Peter's criteria)
Samuel Katsuyuki Shinjo, Adriana Maluf Elias Sallum, Clovis Artur Silva, Suely Kazue Nagahashi Marie   +3 more
doaj   +1 more source

The clinical features of juvenile dermatomyositis: A single-centre inception cohort.

Seminars in Arthritis & Rheumatism, 2022
INTRODUCTION Juvenile Dermatomyositis (JDM), a severe and rare autoimmune disease, is the most common idiopathic inflammatory myopathy in children. We describe the clinical features of a large single-centre cohort.
P. Cancarini, T. Nozawa, Kristi Whitney, Audrey Bell‐Peter, Jo-Anne Marcuz, A. Taddio, Jesssica Guo, Saunya Dover, B. Feldman   +8 more
semanticscholar   +1 more source

Updates on Interferon in Juvenile Dermatomyositis: Pathogenesis and Therapy

Current Opinion in Rheumatology, 2021
Purpose of review This review provides updates regarding the role of interferon (IFN) in juvenile dermatomyositis (JDM), including comparison to interferonopathies and therapeutic implications.
Hanna Kim
semanticscholar   +1 more source

Adult and juvenile dermatomyositis treatment

Journal of Cosmetic Dermatology, 2022
Dermatomyositis is a rare autoimmune inflammatory condition affecting skin and muscles. The disease can be seen in both adults and children. It can be associated with malignancy.
Anant D Patil, Jun Lu, M. Kassir, Mahsa Babaei, M. Goldust   +4 more
semanticscholar   +1 more source

Clinical and autoantibody phenotypes of juvenile dermatomyositis

Rheumatology, 2022
Juvenile dermatomyositis (JDM) is a heterogeneous autoimmune inflammatory myositis with symmetrical proximal muscle weakness and a characteristic rash. Juvenile dermatomyositis is characterized by variable presentation and phenotypes.
O. Boyarchuk, Anna Kuka, I. Yuryk
semanticscholar   +1 more source

Transcriptomes of peripheral blood mononuclear cells from juvenile dermatomyositis patients show elevated inflammation even when clinically inactive

bioRxiv, 2021
In juvenile dermatomyositis (JDM), the most common pediatric inflammatory myopathy, weakness is accompanied by a characteristic rash that often becomes chronic and is associated with vascular damage.
E. Roberson, R. Mesa, Gabrielle A Morgan, Li Cao, Wilfredo Marin, L. Pachman   +5 more
semanticscholar   +1 more source