Results 51 to 60 of about 267,960 (152)

Knockdown of mitotically associated long non‐coding RNA dysregulates endothelial functions, transcriptome and proteome

The Journal of Physiology, EarlyView.
Abstract figure legend Downregulation of mitotically associated long non‐coding RNA (MANCR) disturbs transcriptome and proteome in endothelial cells, possibly leading to endothelial and vascular dysfunction in preeclampsia. Abstract Preeclampsia (PE) is a hypertensive disorder during pregnancy, which is characterized by a wide spectrum of endothelial ...
Si‐Yan Zhang, Chi Zhou, Jing Zheng
wiley   +1 more source

Juvenile dermatomyositis with vasculopathy [PDF]

, 2022
Juvenile dermatomyositis (JDM) is rare, but serious disease with many possible complications. Hallmarks of this disease are heliotrope erythema, periorbital edema and Gottrone papules combined with symmetric proximal muscle weakness that usually slowly ...
Kovačević, Mia, Kujundžić, Magdalena, Frković, Marijana   +2 more
core   +1 more source

Superimposed segmental manifestation of juvenile amyopathic dermatomyositis in a 9-year-old boy

Indian Journal of Dermatology, 2017
Dermatomyositis is a well-known autoimmune disorder. On the other hand, juvenile amyopathic dermatomyositis (JADM) occurs rather rarely. Here, we report an unusual case in a 9-year-old Turkish boy showing a unilateral linear inflammatory skin lesion that
Isil Bulur, Hilal Kaya Erdogan, Zeynep Nurhan Saracoglu, Rudolf Happle, Funda Canaz   +4 more
doaj   +1 more source

Macrophage activation syndrome due to juvenile amyopathic dermatomyositis with atypical onset

Turkderm Turkish Archives of Dermatology and Venereology, 2022
Macrophage activation syndrome (MAS) is a life-threatening condition associated with rheumatic diseases. It is rarely reported in juvenile dermatomyositis.
Esma İnan Yüksel, Betül Demir, Metin kaya Gürgöze, Ilknur Calik   +3 more
doaj   +1 more source

Economic Burden and Treatment Patterns Among Patients Diagnosed With Vitiligo in Japan: An Observational Retrospective Cohort Study

The Journal of Dermatology, Volume 53, Issue 11, Page 1615-1625, November 2026.
ABSTRACT Vitiligo, a common and chronic depigmentation disorder, significantly impacts patients' quality of life and exerts a substantial economic burden. The deleterious impact of vitiligo can be exacerbated by comorbid conditions, including psychiatric and autoimmune conditions.
Naoki Oiso, Kent A. Hanson, Ahmed M. Soliman, Chao Li, Manabu Taura, Daniel Mercer, Andrew Rava, Danielle Bynoe, Haiyan Sun, Tamio Suzuki   +9 more
wiley   +1 more source

Inverse Gottron’s sign in Anti TIF1 gamma positive juvenile dermatomyositis [PDF]

Romanian Journal of Rheumatology
Dermatomyositis is a rare idiopathic inflammatory myopathy characterized by distinctive cutaneous findings and proximal muscle weakness. We describe a 15-year-old girl who presented with a six-month history of heliotrope rash and V-sign erythema ...
Subash Mohan Thulasi, Saranya Chinnadurai, Sornavalli Valliappan, Yohidha Balamurugan   +3 more
doaj   +1 more source

Anasarca as the presenting symptom of juvenile dermatomyositis: a case series

Pediatric Rheumatology Online Journal, 2021
Background Juvenile Dermatomyositis (JDM) is an autoimmune disease that typically presents with classic skin rashes and proximal muscle weakness. Anasarca is a rare manifestation of this disease and is associated with a more severe and refractory course,
Emily E. Schildt, Deirdre De Ranieri
doaj   +1 more source

Multicenter Clinical Comparison Between Anti‐NXP2 and Anti‐TIF1‐γ Antibody‐Positive Myositis, and Analysis of the Clinical Significance of Anti‐NXP2 Antibody Titers in Idiopathic Inflammatory Myopathies

The Journal of Dermatology, Volume 53, Issue 11, Page 1626-1637, November 2026.
ABSTRACT We aimed to measure anti‐nuclear matrix protein 2 antibody (anti‐NXP2) titers in patients with anti‐NXP2‐positive idiopathic inflammatory myopathies, investigate whether these titers are associated with clinical manifestations, malignancy risk, and treatment response, and compare the clinical and serological features between anti‐NXP2‐positive
Satoshi Kamiya, Mariko Ogawa‐Momohara, Yoshinao Muro, Yuta Yamashita, Satoko Yuasa, Masato Kakeda, Kimiko Nakajima, Hiroyuki Morita, Mitsuyo Kinjo, Takako Hashimoto, Ken Yoshida, Takuya Takeichi, Haruka Koizumi, Norika Akashi, Eori Noda, Masashi Akiyama   +15 more
wiley   +1 more source

Unilateral Heliotrope Rash in Juvenile Dermatomyositis: An Unusual Presentation of an Underlying Serious Disease

Case Reports in Rheumatology, 2014
Background. Heliotrope rash is one of the characteristic skin manifestations of juvenile dermatomyositis. It is a reddish-purple rash on the upper eyelids that is usually bilateral. Case Presentation.
Ghada Al-Janobi, Hisham Alkhalidi, Mohammed A. Omair   +2 more
doaj   +1 more source

Diagnostic utility of inflammatory markers in formalin‐fixed and paraffin‐embedded muscle biopsies for idiopathic inflammatory myopathies

Histopathology, Volume 89, Issue 4, Page 699-709, October 2026.
Formalin‐fixed, paraffin‐embedded (FFPE) muscle tissue supports robust immunohistochemical detection of MHC II, MxA, and p62 with performance comparable to frozen sections. This approach reliably identifies the pathological signatures of inclusion body myositis, dermatomyositis, immune‐mediated necrotizing myopathy, and overlap myositis, enhancing the ...
Chinnawut Suriyonplengsaeng, Jariya Waisayarat   +1 more
wiley   +1 more source