Results 41 to 50 of about 378,540 (249)

The von Willebrand Factor Antigen Reflects the Juvenile Dermatomyositis Disease Activity Score

Biomedicines, 2023
Objective: This study determined if an accessible, serologic indicator of vascular disease activity, the von Willebrand factor antigen (vWF:Ag), was useful to assess disease activity in children with juvenile dermatomyositis (JDM), a rare disease, but ...
Ellie Gibbs, Amer M. Khojah, Gabrielle A Morgan, L. Ehwerhemuepha, L. Pachman   +4 more
semanticscholar   +1 more source

An 8-year-old-girl with juvenile dermatomyositis and autoimmune thyroiditis in Tanzania: a case report

Journal of Medical Case Reports, 2021
Background Juvenile dermatomyositis is an inflammatory disease of muscles, skin, and blood vessels of unknown cause affecting all age and ethnic groups, with a reported incidence of 1.9–4.1 per million.
Fatima Mussa, Neema Nalitolela, Francis Fredrick   +2 more
doaj   +1 more source

Juvenile dermatomyositis and nephrotic syndrome: A case report and a mini literature review

Frontiers in Pediatrics, 2023
BackgroundRenal involvement is rarely reported in juvenile dermatomyositis and may be caused by the toxic effects of myoglobinuria or an autoimmune reaction. We report a case of dermatomyositis and nephrotic syndrome in a child to explore the association
Weiran Zhou, Linlin Dong, Xuemei Liu, Chunhua Dong, Hongxia Zhang   +4 more
doaj   +1 more source

Juvenile dermatomyositis. Where are we now?

Clinical and Experimental Rheumatology, 2022
Juvenile onset idiopathic inflammatory myopathy (IIM) has many similarities and distinct differences from adult-onset disease. This review will focus on recent developments in understanding and treatment of juvenile dermatomyositis (JDM), the most common
L. McCann, P. Livermore, M. Wilkinson, L. Wedderburn   +3 more
semanticscholar   +1 more source

Distinct by Design: Unraveling the Unique Clinical and Transcriptomic Identity of Juvenile Scleromyositis Overlap Compared to Juvenile Systemic Sclerosis and Juvenile Dermatomyositis: Implications for Care and Pathogenesis. [PDF]

ACR Open Rheumatol
Robinson AD, Pain CE, Morgan GA, Sanyal A, Chaparala S, Pachman LM, Torok KS.   +6 more
europepmc   +2 more sources

Erythroderma as a presenting sign of juvenile overlap syndrome

Indian Journal of Paediatric Dermatology, 2023
Juvenile dermatomyositis (JDM), which is rarely presented with erythroderma, and juvenile morphea are both autoimmune connective tissue diseases. We report a 14-year-old male child with resistant generalized erythroderma and mild proximal muscle weakness
Sarah Hamdy Soliman, Sameh Sarsik, Nehal Mohamed Elshebiny, Rania Ahmed El-Tatawy, Noha Nabil Doghaim, Nesrin Sabry Gomaa   +5 more
doaj   +1 more source

A rare case of suspected lupus erythematosus panniculitis as the presenting skin feature of juvenile dermatomyositis: A case report

SAGE Open Medical Case Reports, 2022
Juvenile dermatomyositis is a rare autoimmune myopathy of childhood, associated with systemic vasculopathy, primarily affecting the capillaries. Panniculitis is seen histologically in about 10% of patients with dermatomyositis; however, its clinical ...
Dylan C Ginter, Michele L Ramien, Marie-Anne Brundler, Laura C Swaney, Paivi MH Miettunen, Nadia JC Luca   +5 more
doaj   +1 more source

Role of CD14+ monocyte-derived oxidised mitochondrial DNA in the inflammatory interferon type 1 signature in juvenile dermatomyositis

Annals of the Rheumatic Diseases, 2022
Objectives To define the host mechanisms contributing to the pathological interferon (IFN) type 1 signature in Juvenile dermatomyositis (JDM). Methods RNA-sequencing was performed on CD4+, CD8+, CD14+ and CD19+ cells sorted from pretreatment and on ...
M. Wilkinson, D. Moulding, T. McDonnell, M. Orford, C. Wincup, Joanna Y J Ting, Georg W Otto, Restuadi Restuadi, D. Kelberman, C. Papadopoulou, S. Castellano, S. Eaton, C. Deakin, E. Rosser, L. Wedderburn   +14 more
semanticscholar   +1 more source

Case of a fatal lung disease in a child with juvenile dermatomyositis

Zdorovʹe Rebenka, 2017
The article presents a case of a fatal lung disease in a child with juvenile dermatomyositis. Juvenile dermatomyositis is a serious disease with an unpredictable course, and lung damage in juvenile dermatomyositis is one of the most severe manifestations
O.A. Oshlianska, L.I. Omelchenko, L.F. Slepova, O.P. Gladyshko, V.G. Ivanova, V.V. Krat   +5 more
doaj   +1 more source

JAK inhibitors are effective in a subset of patients with juvenile dermatomyositis: a monocentric retrospective study.

Rheumatology, 2021
OBJECTIVE To evaluate the efficacy and safety of JAK inhibitors (JAKi) in juvenile dermatomyositis (JDM). METHODS We conducted a single-center retrospective study of patients with JDM treated by JAKi with a follow-up of at least 6 months. Proportion of
Tom Le Voyer, C. Gitiaux, F. Authier, C. Bodemer, I. Melki, P. Quartier, F. Aeschlimann, A. Isapof, J. Herbeuval, V. Bondet, J. Charuel, M. Frémond, D. Duffy, M. Rodero, B. Bader-Meunier   +14 more
semanticscholar   +1 more source