Results 41 to 50 of about 10,614 (207)

Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease. [PDF]

, 2013
OBJECTIVES: To study muscle biopsy tissue from patients with juvenile dermatomyositis (JDM) in order to test the reliability of a score tool designed to quantify the severity of histological abnormalities when applied to biceps humeri in addition to ...
Amato, Anthony A, Banwell, Brenda, Bove, Kevin E, Charman, Susan C, Corse, Andrea M, Emslie-Smith, Alison M, Holton, Janice L, Jacques, Thomas S, Li, Charles K, Lundberg, Ingrid E, Marie, Suely KN, Minetti, Carlo, Nennesmo, Inger, Pilkington, Clarissa A, Rushing, Elisabeth J, Sallum, Adriana ME, Sewry, Caroline, UK Juvenile Dermatomyositis Research Group, Varsani, Hemlata, Wedderburn, Lucy R   +19 more
core   +3 more sources

Resolution of calcinosis using bisphosphonates in overlap syndrome – a case report

BMC Rheumatology, 2021
Introduction Calcinosis cutis is a common complication of pediatric rheumatologic diseases. However, there is currently no consensus on first-line treatment.
Mitchell Platter, Brian Pugmire, Reshma Patel   +2 more
doaj   +1 more source

Predictors of survival in a cohort of patients with polymyositis and dermatomyositis: effect of corticosteroids, methotrexate and azathioprine [PDF]

, 2012
Introduction: The idiopathic inflammatory myopathies are rare diseases for which data regarding the natural history, response to therapies and factors affecting mortality are needed.
Crofford, Leslie J., MacDonald, Paul M., Phillips, Kristine, Schiopu, Elena, Somers, Emily C.   +4 more
core   +3 more sources

Erythematous scaling lesions of the face, dorsal fingers, elbows, and knees together with symmetrical muscle weakness in a child

Clinical Case Reports, 2019
Juvenile dermatomyositis shows characteristic skin lesions. However, this does not rule out co‐occurring other autoimmune diseases, which may be more prominent regarding skin manifestations.
Aleksander Markovic, Volker Schuster, Jan‐Christoph Simon, Manfred Kunz   +3 more
doaj   +1 more source

A Case of Juvenile Dermatomyositis Manifesting Inflammatory Epidermal Nevus-Like Skin Lesions: Unrecognized Cutaneous Manifestation of Blaschkitis?

Allergology International, 2010
Background: Juvenile dermatomyositis is potentially life threatening rare autoimmune illness that mainly affects muscle and skin. Cutaneous features are useful in establishing the diagnosis of this disease.
Yuji Takahashi, Hiroyuki Murota, MasahitoTarutani, Shigetoshi Sano, Takeshi Okinaga, Koji Tominaga, Toshie Yano, Ichiro Katayama   +7 more
doaj   +1 more source

Risk factors associated with calcinosis of juvenile dermatomyositis [PDF]

, 2008
OBJETIVO: Identificar fatores de risco associados à calcinose em crianças e adolescentes com dermatomiosite juvenil. MÉTODOS: Prontuários de 54 pacientes com dermatomiosite juvenil foram estudados.
AIKAWA, Nádia E., DORIA-FILHO, Ulysses, LIPHAUS, Bernadete L., MARIE, Suely K. N., PIVATO, Francine C. M. M., SALLUM, Adriana M. E., SILVA, Clovis A. A.   +6 more
core   +3 more sources

Juvenile Dermatomyositis: A 20-year Retrospective Analysis of Treatment and Clinical Outcomes

Pediatrics and Neonatology, 2015
Juvenile dermatomyositis is a rare childhood multisystem autoimmune disease involving primarily the skin and muscles, and it may lead to long-term disability.
Chi Sun, Jyh-Hong Lee, Yao-Hsu Yang, Hsin-Hui Yu, Li-Chieh Wang, Yu-Tsan Lin, Bor-Luen Chiang   +6 more
doaj   +1 more source

Favorable outcomes with reduced steroid use in juvenile dermatomyositis

Pediatric Rheumatology Online Journal, 2021
Background High-intensity glucocorticoid regimens are commonly used to induce and maintain remission in Juvenile Dermatomyositis but are associated with several adverse side-effects.
Amir B. Orandi, Lampros Fotis, Jamie Lai, Hallie Morris, Andrew J. White, Anthony R. French, Kevin W. Baszis   +6 more
doaj   +1 more source

A recipe for myositis : nuclear factor κB and nuclear factor of activated T-cells transcription factor pathways spiced up by cytokines [PDF]

, 2017
Nuclear factor κB (NF-κB) is a well-known pro-inflammatory transcription factor that regulates the expression of the tissue’s immune-active components, which include cytokines, chemokines and adhesion molecules.
De Paepe, Boel
core   +3 more sources

Anti-nuclear matrix protein 2 antibody-associated juvenile dermatomyositis with gastrointestinal perforations was successfully treated with traditional therapeutic drugs combined with vedolizumab: a case report after a long-term follow-up and a review of the literature

Frontiers in Pediatrics
Gastrointestinal perforation in patients with juvenile dermatomyositis has been reported as a life-threatening complication in the literature. However, effective treatment of juvenile dermatomyositis with gastrointestinal perforation remains challenging.
Xue-mei Xu, Shuang Ye, Ying-ying Jin, Chen-xi Liu, Sheng-fang Bao, Hua Huang, Fei Ding, Zhen Yang, Yan-liang Jin   +8 more
doaj   +1 more source