Results 21 to 30 of about 267,960 (152)

Clinical and autoantibody phenotypes of juvenile dermatomyositis

, 2022
Juvenile dermatomyositis (JDM) is a heterogeneous autoimmune inflammatory myositis with symmetrical proximal muscle weakness and a characteristic rash. Juvenile dermatomyositis is characterized by variable presentation and phenotypes.
Iryna Yuryk, Boyarchuk, Oksana, Kuka, Anna, Oksana Boyarchuk, Anna Kuka, Yuryk, Iryna   +5 more
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Juvenile Dermatomyositis

Journal of Rheumatic Diseases, 2022
Juvenile dermatomyositis (JDM) is a systemic capillary vasculopathy. Patients present with proximal muscle weakness, raised muscle enzymes, and pathognomic skin rashes such as heliotrope rash, Gottron's papules. Main complications are calcinosis, lipodystrophy, osteoporosis. Complement-mediated damage of vessels is a major mechanism. Magnetic resonance
openaire   +3 more sources

Validation of a score tool for measurement of histological severity in juvenile dermatomyositis and association with clinical severity of disease. [PDF]

, 2013
OBJECTIVES: To study muscle biopsy tissue from patients with juvenile dermatomyositis (JDM) in order to test the reliability of a score tool designed to quantify the severity of histological abnormalities when applied to biceps humeri in addition to ...
Pilkington, Clarissa A, Varsani, Hemlata, Marie, Suely KN, Lundberg, Ingrid E, Sallum, Adriana M E, Banwell, Brenda, Sallum, Adriana ME, Corse, Andrea M, Charman, Susan C, Jacques, Thomas S, Amato, Anthony A, Bove, Kevin E, Emslie-Smith, Alison M, Marie, Suely K N, Holton, Janice L, Nennesmo, Inger, Rushing, Elisabeth J, UK Juvenile Dermatomyositis Research Group, Li, Charles K, Amato, Anthony, Minetti, Carlo, Sewry, Caroline, Wedderburn, Lucy R, Bove, KE, Banwell, B, Varsani, H, Emslie-Smith, AM, Marie, SKN, Corse, AM, Li, CK, Jacques, TS, Amato, AA, Charman, SC, Li CK, Sallum AM, Varsani H, Banwell B, Charman SC, Marie SK, Sewry C, Emslie-Smith AM, Amato AA, Lundberg IE, Holton JL, Wedderburn LR, Corse AM, Nennesmo I, Pilkington CA, Jacques TS, Minetti C, Bove KE, Rushing EJ   +51 more
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A national registry for juvenile dermatomyositis and other paediatric idiopathic inflammatory myopathies: 10 years' experience; the Juvenile Dermatomyositis National (UK and Ireland) Cohort Biomarker Study and Repository for Idiopathic Inflammatory Myopathies [PDF]

, 2010
Objectives: The paediatric idiopathic inflammatory myopathies (IIMs) are a group of rare chronic inflammatory disorders of childhood, affecting muscle, skin and other organs.
Juvenile Dermatomyositis Research Group, Martin, N, Lucy R. Wedderburn, Sally Smith, Davidson, J.E., Wedderburn, L.R., Smith, S., Neil Martin, Pilkington, C.A., Gardner-Medwin, J. [JD Research Group], Joyce E. Davidson, Krol, P., Petra Krol, Murray, K., Kevin Murray, Clarissa A. Pilkington   +15 more
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Skeletal muscle major histocompatibility complex class I and II expression differences in adult and juvenile dermatomyositis

Clinics, 2012
OBJECTIVE: To analyze major histocompatibility complex expression in the muscle fibers of juvenile and adult dermatomyositis. METHOD: In total, 28 untreated adult dermatomyositis patients, 28 juvenile dermatomyositis patients (Bohan and Peter's criteria)
Samuel Katsuyuki Shinjo, Adriana Maluf Elias Sallum, Clovis Artur Silva, Suely Kazue Nagahashi Marie   +3 more
doaj   +1 more source

Erythematous scaling lesions of the face, dorsal fingers, elbows, and knees together with symmetrical muscle weakness in a child

Clinical Case Reports, 2019
Juvenile dermatomyositis shows characteristic skin lesions. However, this does not rule out co‐occurring other autoimmune diseases, which may be more prominent regarding skin manifestations.
Aleksander Markovic, Volker Schuster, Jan‐Christoph Simon, Manfred Kunz   +3 more
doaj   +1 more source

Resolution of calcinosis using bisphosphonates in overlap syndrome – a case report

BMC Rheumatology, 2021
Introduction Calcinosis cutis is a common complication of pediatric rheumatologic diseases. However, there is currently no consensus on first-line treatment.
Mitchell Platter, Brian Pugmire, Reshma Patel   +2 more
doaj   +1 more source

A Case of Juvenile Dermatomyositis Manifesting Inflammatory Epidermal Nevus-Like Skin Lesions: Unrecognized Cutaneous Manifestation of Blaschkitis?

Allergology International, 2010
Background: Juvenile dermatomyositis is potentially life threatening rare autoimmune illness that mainly affects muscle and skin. Cutaneous features are useful in establishing the diagnosis of this disease.
Yuji Takahashi, Hiroyuki Murota, MasahitoTarutani, Shigetoshi Sano, Takeshi Okinaga, Koji Tominaga, Toshie Yano, Ichiro Katayama   +7 more
doaj   +1 more source

Anti-nuclear matrix protein 2 antibody-associated juvenile dermatomyositis with gastrointestinal perforations was successfully treated with traditional therapeutic drugs combined with vedolizumab: a case report after a long-term follow-up and a review of the literature

Frontiers in Pediatrics
Gastrointestinal perforation in patients with juvenile dermatomyositis has been reported as a life-threatening complication in the literature. However, effective treatment of juvenile dermatomyositis with gastrointestinal perforation remains challenging.
Xue-mei Xu, Shuang Ye, Ying-ying Jin, Chen-xi Liu, Sheng-fang Bao, Hua Huang, Fei Ding, Zhen Yang, Yan-liang Jin   +8 more
doaj   +1 more source

Juvenile Dermatomyositis: A 20-year Retrospective Analysis of Treatment and Clinical Outcomes

Pediatrics and Neonatology, 2015
Juvenile dermatomyositis is a rare childhood multisystem autoimmune disease involving primarily the skin and muscles, and it may lead to long-term disability.
Chi Sun, Jyh-Hong Lee, Yao-Hsu Yang, Hsin-Hui Yu, Li-Chieh Wang, Yu-Tsan Lin, Bor-Luen Chiang   +6 more
doaj   +1 more source