Results 31 to 40 of about 267,960 (152)

Favorable outcomes with reduced steroid use in juvenile dermatomyositis

Pediatric Rheumatology Online Journal, 2021
Background High-intensity glucocorticoid regimens are commonly used to induce and maintain remission in Juvenile Dermatomyositis but are associated with several adverse side-effects.
Amir B. Orandi, Lampros Fotis, Jamie Lai, Hallie Morris, Andrew J. White, Anthony R. French, Kevin W. Baszis   +6 more
doaj   +1 more source

The Vasculopathy of Juvenile Dermatomyositis [PDF]

Frontiers in Pediatrics, 2018
Juvenile dermatomyositis (JDM) is a rare autoimmune disease mainly characterized by muscle and skin involvement. Vasculopathy is considered central to the pathogenesis of the disease. The exact nature of vasculopathy is not yet understood but it is a complex process with both an inflammatory and a non-inflammatory, occlusive component.
Charalampia Papadopoulou, Charalampia Papadopoulou, Liza J. McCann   +2 more
openaire   +4 more sources

Juvenile amyopathic dermatomyositis

Dermatology Online Journal, 2005
A 3-year-old girl presented with a 6-month history of multiple, light-pink, flat-topped papules over the dorsal aspects of the metacarpophalangeal and interphalangeal joints of the hands and feet. Nailfold telangiectases, ragged cuticles, and a heliotrope color of the upper eyelids were also evident, but there was no clinical evidence of muscle ...
Henning, J Scott, Witkiewicz, Agnieszka, Schaffer, Julie V, Orlow, Seth J   +3 more
openaire   +4 more sources

Comparison between treatment naive juvenile and adult dermatomyositis muscle biopsies: difference of inflammatory cells phenotyping

Advances in Rheumatology, 2018
Background Different inflammatory cells (i.e., CD4, CD8, CD20 and CD68) are involved in pathogenesis of DM muscle. In this context, the aim of this study was to assess and compare these inflammatory cell phenotyping in muscle samples of treatment naive ...
Samuel Katsuyuki Shinjo, Adriana Maluf Elias Sallum, Sueli Mieko Oba-Shinjo, Marilda Guimarães Silva, Clovis Artur Silva, Suely Kazue Nagahashi Marie   +5 more
doaj   +1 more source

Juvenile idiopathic inflammatory myopathies: the value of magnetic resonance imaging in the detection of muscle involvement

São Paulo Medical Journal, 2000
CONTEXT: One of the major current challenges related to juvenile idiopathic inflammatory myopathy is the search for highly sensitive and specific non-invasive methods for diagnosis as well as for follow-up.
Maria Odete Esteves Hilário, Hélio Yamashita, Daniela Lutti, Cláudio Len, Maria Teresa Terreri, Henrique Lederman   +5 more
doaj   +1 more source

Severe Phenotype in an Indian Family With Progressive Pseudorheumatoid Arthropathy of Childhood

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive pseudorheumatoid arthropathy of childhood (PPAC) is a rare autosomal recessive progressive condition that affects the cartilage of joints and bones. The symptoms of PPAC include stiffness of the joints, bony swelling of the toes and fingers, short stature, kyphosis, and muscle weakness.
Narinder Singh, Arpita Neogi, Liliane H. Gibbs, Jagdish Soni, Elizabeth Chao, Virginia Kimonis   +5 more
wiley   +1 more source

Case Report: IVIG causing bilateral papilledema and increased intracranial hypertension in patients with anti-TIF-1γ antibody-positive JDM

Frontiers in Pediatrics
Juvenile dermatomyositis is a systemic autoimmune disease characterized by progressive proximal muscle weakness, pathognomonic rashes, and often the presence of myositis-specific antibodies.
Sarah Baluta, Ivana Stojkic, Kyla Driest, Christina Schutt   +3 more
doaj   +1 more source

Respiratory symptoms as initial manifestations of interstitial lung disease in clinically amyopathic juvenile dermatomyositis: a case report with literature review

BMC Pediatrics, 2021
Background Clinically amyopathic juvenile dermatomyositis (CAJDM) is a clinical subgroup of juvenile dermatomyositis (JDM), characterized by JDM rashes with little or no clinically evident muscle weakness.
Jingyi Xia, Gaoli Jiang, Tingting Jin, Quanli Shen, Yangyang Ma, Libo Wang, Liling Qian   +6 more
doaj   +1 more source

Assessment of the trophological status of children with rheumatic diseases

Zdorovʹe Rebenka, 2021
Background. Analyzing modern medical literature, it can be noted that in pediatric rheumatology, insufficient attention is paid to assessing the trophological status of sick children.
L.I. Omelchenko, O.M. Mukvich, E.A. Belskaya, I.V. Dudka, T.A. Ludvik   +4 more
doaj   +1 more source

From Interferon Signature to the Clinical Landscape: Type I Interferonopathies

Arthritis &Rheumatology, EarlyView.
Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz, Seza Ozen, Hacer Neslihan Bildik, Canberk Ipsir, Dilara Unal, Saliha Esenboga, Begum Cicek, Mehmet Emin Seker, Fatima Aerts‐Kaya, Seher Sener, Mehmet Orhan Erkan, Hanife Avci, Deniz Cagdas, Ilhan Tezcan   +13 more
wiley   +1 more source