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Juvenile Dermatomyositis [PDF]

open access: yesCurrent Rheumatology Reports, 2011
Juvenile dermatomyositis (JDM) is a rare, often chronic autoimmune disease with onset during childhood. It is characterized by weakness in proximal muscles and pathognomonic skin rashes. Although the etiology remains unclear, it has been proposed that JDM is caused by a vasculopathy within the muscle tissue and multiple other organ systems of ...
Michelle, Batthish, Brian M, Feldman
core   +8 more sources
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Dermatomyositis und juvenile Dermatomyositis

Zeitschrift für Rheumatologie, 2022
Dermatomyositis (DM) is an inflammatory multisystem disease of unknown etiology, which can already occur in children but first onset can also be in older adulthood. Myalgia and muscle weakness can occur later in the course of the disease or even be completely absent in some forms.
F. Dressler, B. Maurer
semanticscholar   +3 more sources

Rapid Improvement in Recalcitrant Cutaneous Juvenile Dermatomyositis With Anifrolumab Treatment.

JAMA dermatology, 2023
This case report describes a 14-year-old girl with juvenile dermatomyositis who presented with a 6-year history of a pruritic, photosensitive eruption involving her face, neck, trunk, and extremities and was successfully treated with anifrolumab.
Katharina S. Shaw   +6 more
semanticscholar   +1 more source

Shared and Distinctive Transcriptomic and Proteomic Pathways in Adult and Juvenile Dermatomyositis

Arthritis & Rheumatology, 2023
Transcript and protein expression were interrogated to examine gene locus and pathway regulation in the peripheral blood of active adult dermatomyositis (DM) and juvenile DM patients receiving immunosuppressive therapies.
James M. Ward   +12 more
semanticscholar   +1 more source

Association of Juvenile Dermatomyositis Disease Activity With the Expansion of Blood Memory B and T Cell Subsets Lacking Follicular Markers

Arthritis & Rheumatology, 2023
This study was undertaken to identify blood markers of juvenile dermatomyositis (DM) disease activity (DA), which are needed to improve disease management.
Jacqueline S Gofshteyn   +24 more
semanticscholar   +1 more source

Comparison of clinical and laboratory features and treatment responses in patients with clinically amyopathic juvenile dermatomyositis and classical juvenile dermatomyositis

International Journal of Rheumatic Diseases, 2023
The aim of this study was to compare the clinical and laboratory features, treatment choices and responses, and outcomes between patients with clinically amyopathic juvenile dermatomyositis (CAJDM) and classical juvenile dermatomyositis (JDM).
Deniz Gezgin Yıldırım   +7 more
semanticscholar   +1 more source

Juvenile dermatomyositis

The Indian Journal of Pediatrics, 1996
The clinical profile of 7 children and their follow-up is described. There was female preponderance with mate to female ratio of 1:6. The median age of onset was 6 years. All the patients had skin rash, muscle weakness and abnormal enzyme profile. Muscle biopsy was performed in 6 and was abnormal in all of them.
V, Seth   +3 more
openaire   +4 more sources

Juvenile Dermatomyositis

Pediatric Annals, 2002
Juvenile dermatomyositis (JDM) is a multisystem disease characterized by acute and chronic lymphocytic inflammation of the skeletal muscle and skin. The disease is marked early in its course by the presence of a vasculopathy or vasculitis, and later by the development of calcinosis.
Ann M, Reed, Maricarmen, Lopez
  +7 more sources

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