Results 71 to 80 of about 347,568 (271)

Comparison between treatment naive juvenile and adult dermatomyositis muscle biopsies: difference of inflammatory cells phenotyping

Advances in Rheumatology, 2018
Background Different inflammatory cells (i.e., CD4, CD8, CD20 and CD68) are involved in pathogenesis of DM muscle. In this context, the aim of this study was to assess and compare these inflammatory cell phenotyping in muscle samples of treatment naive ...
Samuel Katsuyuki Shinjo, Adriana Maluf Elias Sallum, Sueli Mieko Oba-Shinjo, Marilda Guimarães Silva, Clovis Artur Silva, Suely Kazue Nagahashi Marie   +5 more
doaj   +1 more source

Plasma exosomes from children with juvenile dermatomyositis are taken up by human aortic endothelial cells and are associated with altered gene expression in those cells [PDF]

, 2019
BACKGROUND: The pathology of juvenile dermatomyositis (JDM) is characterized by prominent vessel wall and perivascular inflammation. This feature of the disease has remained unexplained and under-investigated. We have hypothesized that plasma exosomes,
Chen, Yanmin, Holmes, Lucy, Hu, Zihua, Jarvis, James N., Jiang, Kaiyu, Karasawa, Rie, O’Neil, Kathleen M.   +6 more
core   +1 more source

Design of the muscles in motion study: a randomized controlled trial to evaluate the efficacy and feasibility of an individually tailored home-based exercise training program for children and adolescents with juvenile dermatomyositis [PDF]

, 2012
BACKGROUND: Juvenile dermatomyositis (JDM) is a rare, often chronic, systemic autoimmune disease of childhood, characterized by inflammation of the microvasculature of the skeletal muscle and skin. Prominent clinical features include significant exercise
Anneli C Langbroek-Amersfoort, Annet van Royen-Kerkhof, Esther A Habers, Marco van Brussel, Tim Takken   +4 more
core   +2 more sources

Case Report: IVIG causing bilateral papilledema and increased intracranial hypertension in patients with anti-TIF-1γ antibody-positive JDM

Frontiers in Pediatrics
Juvenile dermatomyositis is a systemic autoimmune disease characterized by progressive proximal muscle weakness, pathognomonic rashes, and often the presence of myositis-specific antibodies.
Sarah Baluta, Ivana Stojkic, Kyla Driest, Christina Schutt   +3 more
doaj   +1 more source

Alu Overexpression Leads to an Increased Double‐Stranded RNA Signature in Dermatomyositis

Arthritis &Rheumatology, EarlyView.
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the noncoding genome in disease pathogenesis.
Rayan Najjar, Andrew Mammen, Tomas Mustelin   +2 more
wiley   +1 more source

Disease course, frequency of relapses and survival of 73 patients with juvenile or adult dermatomyositis [PDF]

, 2005
Objective Our aim is to present the disease course, frequency of relapses and survival of juvenile and adult dermatomyositis (JDM/DM) patients. Methods Analysis was performed using data on 73 patients. The median follow-up for 38 JDM patients was
Balogh, Zsolt, Borgulya, Gábor, Constantin, Tamás, Dankó, K., Fekete, György, Garami, Miklós, Molnár, K., Ponyi, Andrea, Szalai, Zsuzsanna, Tefner, I.   +9 more
core  

Bone mineral density of Brazilian girls with juvenile dermatomyositis [PDF]

, 2005
We measured bone mineral density (BMD) in girls with juvenile dermatomyositis (JDM) considering multiple factors in order to determine if it could be used as a predictor of reduction in bone mass.
Castro, Tania Caroline Monteiro de, Fonseca, A.s.m. da, Hilário, Maria Odete Esteves, Len, Claudio Arnaldo, Szejnfeld, Vera Lucia, Terreri, Maria Teresa Ramos Ascensão   +5 more
core   +2 more sources

Siglec-1 expression on monocytes is associated with the interferon signature in juvenile dermatomyositis and can predict treatment response

Rheumatology, 2021
Objective JDM is a rare chronic immune-mediated inflammatory disease with a predominant role for type I IFN responses. We aimed to determine the potential of Siglec-1 expression on monocytes as a novel IFN-inducible biomarker for disease activity ...
Butsabong Lerkvaleekul, S. Veldkamp, M. M. van der Wal, E. Schatorjé, S. Kamphuis, J. M. van den Berg, P. Muller, W. Armbrust, S. Vastert, J. Wienke, M. Jansen, A. van Royen-Kerkhof, F. van Wijk   +12 more
semanticscholar   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Juvenile dermatomyositis (JDM) and severe pulmonary involvement: case report [PDF]

, 2009
Juvenile dermatomyositis (JDM) is an inflammatory, non-pustular disorder of skeletal muscles and skin. Other organs, such as the lungs, can be involved.
Bugni, Vanessa Monteiro, Castro, Márcia Helena de Oliveira, Hilário, Maria Odete Esteves, Ishigai, Márcia Marcelino de Souza, Silva, Érika Cristina Carneiro da, Terreri, Maria Teresa Ramos Ascensão   +5 more
core   +2 more sources