Results 91 to 100 of about 3,713 (208)

Landscape of potential germline pathogenic variants in select cancer susceptibility genes in patients with adult‐type ovarian granulosa cell tumors

Cancer Medicine, Volume 13, Issue 12, June 2024.
Predicted germline mutations were found in 6.6% of sequenced, FOXL2‐mutated AGCT. Predicted germline CHEK2 were found in 3.5% of this cohort, 2.8 times higher than anticipated. Further prospective investigation into the biology of germline mutations in this population is warranted.
Rebekah M. Summey, Erica Gornstein, Brennan Decker, Kali C. Dougherty, Janet S. Rader, Elizabeth Hopp   +5 more
wiley   +1 more source

Estrone and estradiol concentrations in human ovaries, testes, and adrenals during the first two years of life [PDF]

, 1987
To determine the origin of estrogens in infant blood, we measured estrone (E1) and estradiol (E2) in the gonads of 50 girls and 64 boys who died suddenly between birth and 2 yr of age as well as in the adrenals of 18 of these infant girls and 16 of the ...
Bidlingmaier, F., Dorr, H. G., Eisenmenger, Wolfgang, Knorr, D., Strom, T. M.   +4 more
core   +1 more source

Clinicopathological evaluation of ovarian juvenile granulosa cell tumor: Is fertility-sparing surgery safe?

Reproductive and Developmental Medicine, 2019
Objective: To retrospectively investigate the clinicopathological characteristics of ovarian juvenile granulosa cell tumors (JGCTs) and to evaluate the safety of fertility-sparing surgery.
Lu Guo, Xiao-Cheng Liu, Xiu-Ying Chen, Xi-Rong Xiao, Yu-Qing Qu, Bin Li   +5 more
doaj   +1 more source

Bilateral ovarian juvenile granulosa cell tumor in a neonate with Donohue syndrome: a case report and review of literature

Egyptian Pediatric Association Gazette
Background Hereditary severe insulin resistance syndrome (H-SIRS) is a group of disorders classified into four principal categories: primary insulin receptor defects, lipodystrophies, complex genetic syndromes, and obesity-related H-SIRS.
Amany Reda Elbahbity, Amr Abdelhamid AbouZeid, Mohammad Hassan Mohamed, Mohammad Hassan Elibiary, Soha M. khafagy, Amira Mostafa Rashad, Shaimaa Mahmoud Abdelraouf, Sohair Abdelbaset Zayed, Manal Fawzy Gadalla, Shaimaa Abdelsattar Mohammad   +9 more
doaj   +1 more source

Granulosa cell tumor of the testis in a newborn

Autopsy and Case Reports, 2014
Testicular neoplasms are uncommon tumors of childhood. These tumors comprise the germ cell tumors, and other tumors that may originate from histological testicular components, which are unrelated to the germinal lineage. Among the latter are the sex cord-
Oliver Rojas Claros, Américo Toshiaki Sakai, Horácio Consolmagno, Marcos de Paula Nogueira, Leonardo Abreu Testagrossa, Oscar Eduardo Hidetoshi Fugita   +5 more
doaj   +1 more source

Juvenile granulosa cell tumor in a teenager: a case report

Journal of Pediatric Surgery Case Reports
Introduction: Juvenile granulosa cell tumors (JGCTs) are rare ovarian sex cord–stromal neoplasms that primarily affect young females and are often detected early due to hyperestrogenic manifestations.
Ian Cummings-Ruiz, Nicole A. Martínez-Martínez, Kenneth Avilés-Fernández, Yaiel Rodríguez-Avilés, Victor Ortiz-Justiniano   +4 more
doaj   +1 more source

Juvenile granulosa cell tumor in a transgender male with Ollier disease: A case report. [PDF]

Gynecol Oncol Rep, 2023
Ing BI, Huepenbecker SP, Hameed N, Lu KH.   +3 more
europepmc   +1 more source

Case report of a 3-year-old girl with pleuropulmonary blastoma and family history of a tumor predisposition syndrome with c. 2830 gene mutation in DICER1

Journal of Pediatric Surgery Case Reports, 2015
Pleuropulmonary blastoma (PPB) is a childhood mesenchymal pleural-based tumor that is associated with a germline mutation in DICER1 gene in familial PPB. It occurs most commonly in children between the ages of 2 and 5.
Y. Puckett, J. Howe, D. Vane, A. Agarwal, J.R. Batanian, J. Greenspon   +5 more
doaj   +1 more source

Atualização em etiologia, diagnóstico e manejo da precocidade sexual [PDF]

, 2008
Precocious puberty is defined as the development of secondary sexual characteristics before the age of 8 years in girls and 9 years in boys. Gonadotropin-dependent precocious puberty (GDPP) results from the premature activation of the hypothalamic ...
ARNHOLD, Ivo J. P., BRITO, Vinicius Nahime, LATRONICO, Ana Claudia, MENDONÇA, Berenice Bilharinho   +3 more
core   +2 more sources

A 12-Year-Old Girl with Juvenile Granulosa Cell Tumor of the Ovary, Presenting with Adolescent Hyperprolactinemia, Galactorrhea, and Amenorrhea. [PDF]

Am J Case Rep, 2023
Park H, Goodman CP, Raymond SL, Sundin A, Khan FA, Radulescu A.   +5 more
europepmc   +1 more source