Results 81 to 90 of about 3,652 (213)

Ovarian cysts and tumors as the cause of isosexual pseudoprecocious puberty [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2006
Introduction. Precocious puberty in girls is generally defined as appearance of secondary sexual characteristics before eight years of age. Menarche before the ninth birthday may serve as an additional criterion.
Mitrović Katarina, Zdravković Dragan, Milenković Tatjana, Sedlecki Katarina, Stanković Zoran   +4 more
doaj   +1 more source

Loss of Cx43 in Murine Sertoli Cells Leads to Altered Prepubertal Sertoli Cell Maturation and Impairment of the Mitosis-Meiosis Switch. [PDF]

, 2020
Male factor infertility is a problem in today's society but many underlying causes are still unknown. The generation of a conditional Sertoli cell (SC)-specific connexin 43 (Cx43) knockout mouse line (SCCx43KO) has provided a translational model ...
Behr, Rüdiger, Brehm, Ralph HJ, Distl, Ottmar, Hilbold, Erika, Hoedemaker, Martina, Jung, Klaus, Langeheine, Marion, Metzger, Julia, Rajkovic, Aleksandar, Rode, Kristina, Wilkening, Sandra   +10 more
core   +1 more source

New histopathological and molecular findings in gynecological cancers

International Journal of Gynecology &Obstetrics, Volume 171, Issue S1, Page 109-119, September 2025.
Abstract This review covers significant developments in the pathological classification of gynecological tumors in recent years. Topics covered include The Cancer Genome Atlas (TCGA) Classification of endometrial carcinomas and how to incorporate this into routine reporting, the fact that most synchronous endometrial and ovarian endometrioid carcinomas
W. Glenn McCluggage
wiley   +1 more source

Functional analysis and transcriptional output of the Göttingen minipig genome [PDF]

, 2015
In the past decade the Göttingen minipig has gained increasing recognition as animal model in pharmaceutical and safety research because it recapitulates many aspects of human physiology and metabolism.
Badi, Laura, Berrera, Marco, Bishop, Richard, Certa, Ulrich, Daff, Hamina, Daubenberger, Claudia, Ebeling, Martin, Heckel, Tobias, Khan, Azinwi Phina, Kiialainen, Anna, Kratochwil, Nicole A., Kuhn, Bernd, Küng, Erich, Lekolool, Isaac, Nowaczyk, Corinne, Okoth, Edward, Pelle, Roger, Ravon, Morgane, Ringshandl, Stephan, Schmitt, Georg, Schmucki, Roland, Steiner, Guido   +21 more
core   +9 more sources

Activity and Heterogeneity of Astrocytes in Neurological Diseases: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 6, Issue 9, September 2025.
Astrocytes display heterogeneity in various neurological disorders and behavioral neuropsychiatric disorders. Astrocytes influence the progression of neurological diseases through neuroinflammation, oxidative stress, metabolic abnormalities, intercellular interactions, and a spectrum of other pathophysiological processes.
Shijie Mao, Rui Qiao, Qi Wang, Ling Shen, Daxing Li, Xinchen Huo, Jindou Wang, Kunxuan Liu, Wenjing Chen, Tianhao Zhu, Beicheng Zhang, Shuo Leng, Ying Bai   +12 more
wiley   +1 more source

The Role of Anti‐Müllerian Hormone in Van Cats in Relation to Sex and Reproductive Status

Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.
This study investigates the serum anti‐Müllerian hormone (AMH) concentrations in Van cats across different reproductive statuses. Blood samples were collected from prepubertal, pubertal and neutered male cats; prepubertal; pubertal as well as spayed queens. AMH levels were measured and compared to assess gonadal function and sexual development.
Mehmet Yildiz, Davut Koca, Busra Nur Kilic Yildiz, Muhammed Zeyd Isik, Ali Osman Turgut, Yunus Çetin   +5 more
wiley   +1 more source

Testicular and ovarian Juvenile granulosa cell tumors in children and adolescents: Analysis of 113 patients registered to the German Registry for Rare Pediatric Tumors (STEP)

Cancer, Volume 131, Issue 9, 1 May 2025.
Abstract Background In juvenile granulosa cell tumors (juvGCTs), impaired survival was reported after preoperative tumor rupture, peritoneal metastases, or high mitotic rate (≥20 mitoses per 10 high‐power fields). Therefore, a risk stratification was developed to select patients for chemotherapy. Methods Between 2001 and 2019, 89 female patients and 24
Dominik T. Schneider, Andrea Witowski, Michael Abele, Martin Benesch, Benedikt Bernbeck, Tabea Blessing, Bastian Brummel, Gabriele Calaminus, Ulrich Göbel, Norbert Graf, Christian Vokuhl, Kris Ann P. Schultz, Ines B. Brecht   +12 more
wiley   +1 more source

Virilization and abdominal mass in a newborn female: A case report

Journal of Pediatric Surgery Case Reports, 2017
We describe virilization in a newborn female secondary to bilateral congenital juvenile granulosa cell tumor (JGCT). The patient presented with abdominal mass and ambiguous genitalia at birth, and bilateral ovarian masses were discovered on further ...
Natalie A. Drucker, MD, Brian W. Gray, MD, Johanna Askegard-Giesmann, MD   +2 more
doaj   +1 more source

Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish

, 2013
Mild mutations in BRCA2 (FANCD1) cause Fanconi anemia (FA) when homozygous, while severe mutations cause common cancers including breast, ovarian, and prostate cancers when heterozygous.
BreMiller, Ruth A., Cañestro García, Cristian, Grayl, E. M., He, Xinjun, Johnston, A., Kanki, J. P., Nanda, I., Postlethwait, John H., Rodríguez Marí, Adriana, Schindeler, D., Spitsbergen, J., Titus, T. A., Wilson, Catherine, Yan, Yi-Lin   +13 more
core   +2 more sources

Persistent organic pollutant burden, experimental POP exposure and tissue properties affect metabolic profiles of blubber from grey seal pups [PDF]

, 2018
Persistent organic pollutants (POPs) are toxic, ubiquitous, resist breakdown, bioaccumulate in living tissue and biomagnify in food webs. POPs can also alter energy balance in humans and wildlife.
Bennett, Kimberley A., Debier, Cathy, Eppe, Gauthier, Hall, Ailsa J., Robinson, Kelly J., Thomé, Jean Pierre   +5 more
core   +4 more sources