Results 71 to 80 of about 1,885 (186)

Activity and Heterogeneity of Astrocytes in Neurological Diseases: Molecular Mechanisms and Therapeutic Targets

MedComm, Volume 6, Issue 9, September 2025.
Astrocytes display heterogeneity in various neurological disorders and behavioral neuropsychiatric disorders. Astrocytes influence the progression of neurological diseases through neuroinflammation, oxidative stress, metabolic abnormalities, intercellular interactions, and a spectrum of other pathophysiological processes.
Shijie Mao, Rui Qiao, Qi Wang, Ling Shen, Daxing Li, Xinchen Huo, Jindou Wang, Kunxuan Liu, Wenjing Chen, Tianhao Zhu, Beicheng Zhang, Shuo Leng, Ying Bai   +12 more
wiley   +1 more source

The Role of Anti‐Müllerian Hormone in Van Cats in Relation to Sex and Reproductive Status

Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.
This study investigates the serum anti‐Müllerian hormone (AMH) concentrations in Van cats across different reproductive statuses. Blood samples were collected from prepubertal, pubertal and neutered male cats; prepubertal; pubertal as well as spayed queens. AMH levels were measured and compared to assess gonadal function and sexual development.
Mehmet Yildiz, Davut Koca, Busra Nur Kilic Yildiz, Muhammed Zeyd Isik, Ali Osman Turgut, Yunus Çetin   +5 more
wiley   +1 more source

Juvenile Granulosa Cell Tumor with Elevated Peripheral Interleukin-6 Level Shows Prolonged Fever and Delayed Puberty [PDF]

Juvenile granulosa cell tumor (JGCT), classified as a sex cord-stromal tumor, is a rare neoplasm. This is an instructive case report of JGCT accompanied by augmented interleukin (IL)-6 secretion.
17268, 17269, Okuno, Keisuke, Nishimura, Rei, Kanzaki, Susumu, Kuwamoto, Satoshi, 100000360, 90224873, 791, 60229226, 572, 1855, 100000861, Harada, Tasuku, 100000223, 100000421, 1311, 100001118, 60567189, Horie, Yasushi, 2649, Komatsu, Hiroaki, Ueyama, Jun-ichi, 17270, 17271, Sano, Hiroshi, 2919, 100000139, 40218649, Yoneda, Naohiro   +29 more
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Ovarian granulosa cell tumor : a clinicopathological series [PDF]

, 2018
Introduction: Granulosa cell tumours (GCT) are uncommon neoplasms, accounting for 2-5% of all ovarian carcinomas. The pathogenesis of these tumours is characterised by differentiation towards the follicular granulosa cell.
Zrinzo, Salvina, Aquilina, Annelise, Pisani, David, Brincat, Mark R., Metaraku, Donika, Borg, Eleanor, Muscat Baron, Yves, Micallef, Rachel, Degaetano, James   +8 more
core   +1 more source

Virilization and abdominal mass in a newborn female: A case report

Journal of Pediatric Surgery Case Reports, 2017
We describe virilization in a newborn female secondary to bilateral congenital juvenile granulosa cell tumor (JGCT). The patient presented with abdominal mass and ambiguous genitalia at birth, and bilateral ovarian masses were discovered on further ...
Natalie A. Drucker, MD, Brian W. Gray, MD, Johanna Askegard-Giesmann, MD   +2 more
doaj   +1 more source

Testicular and ovarian Juvenile granulosa cell tumors in children and adolescents: Analysis of 113 patients registered to the German Registry for Rare Pediatric Tumors (STEP)

Cancer, Volume 131, Issue 9, 1 May 2025.
Abstract Background In juvenile granulosa cell tumors (juvGCTs), impaired survival was reported after preoperative tumor rupture, peritoneal metastases, or high mitotic rate (≥20 mitoses per 10 high‐power fields). Therefore, a risk stratification was developed to select patients for chemotherapy. Methods Between 2001 and 2019, 89 female patients and 24
Dominik T. Schneider, Andrea Witowski, Michael Abele, Martin Benesch, Benedikt Bernbeck, Tabea Blessing, Bastian Brummel, Gabriele Calaminus, Ulrich Göbel, Norbert Graf, Christian Vokuhl, Kris Ann P. Schultz, Ines B. Brecht   +12 more
wiley   +1 more source

An 11-year-old girl with juvenile-type granulosa cell tumor of the ovary that recurs in a short time: a case report

Aim: Ovarian tumors with granulosa cells constitute 2-5% of all malignant ovarian tumors. Its incidence among sexcord stromal tumors is over 90%. There are two subtypes of granulosa cell tumors; adult type (95%) and juvenile type(5%).
Vatansever, Doğan, Dönmez, Emin Erhan, Giray, Buak, Taşkıran, Çağatay, Arslan, Oğuz   +4 more
core   +1 more source

Postpartum Cystic Juvenile Granulosa Cell Tumor: A Case Report [PDF]

, 2014
Introduction: Juvenile granulosa cell tumor (JGCT) is a subtype of granulosa cell tumors of the ovary. 80% of JGCT occurs at prepubertal period. And, it is considered to be a slow growing tumor. In addition, gross appearence of it is mostly solid. Herein,
Seçkin, Levent, ŞAHİN, SEVİNÇ, Seçkin, Selda   +2 more
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Adult Type Granulosa Cell Tumor Causing Precocious Pseudopuberty in a 6 Year-old Girl

, 2003
Malignant ovarian tumors are responsible for 2-3% of all cases of precocious pseudo-puberty (PP) in girls. The most common forms of ovarian tumors presenting as PP are the granulosa cell tumors (GCT).
Adal, E, Ilvan, S, S. Ilvan, M. Yildi, Isguven, P, E. Adal, Arslanoglu, I, Yildiz, M, I. Arslanoglu, Yoruk, A, P. Isguven, A. Yoruk   +11 more
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Congenital bilateral juvenile granulosa cell tumor of the ovary in leprechaunism: a case report

, 1993
We report on a case of leprechaunism. In addition to the typical clinical and biochemical features, a bilateral juvenile granulosa cell tumor of the ovaries and cytomegalovirus hepatitis were found.
Cohen A, Gatti R, Fabbretti G, Pesce F, PARENTI, GIANCARLO, Callea F., Brisigotti M   +6 more
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