Results 61 to 70 of about 3,652 (213)

Central precocious puberty and granulosa cell ovarian tumor in an 8-year old female

Pediatric Reports, 2013
Ovarian tumors associated with hormonal changes of the peripheral iso-sexual precocious puberty are of common presentation. We describe here a rare case of juvenile granulosa cell tumor in a female with central precocious puberty (CPP).
Valeria Calcaterra, Ghassan Nakib, Gloria Pelizzo, Barbara Rundo, Gaetana Anna Rispoli, Stella Boghen, Federico Bonetti, Barbara Del Monte, Chiara Gertosio, Daniela Larizza   +9 more
doaj   +1 more source

Reproductive and developmental effects of phthalate diesters in females. [PDF]

, 2013
Phthalate diesters, widely used in flexible plastics and consumer products, have become prevalent contaminants in the environment. Human exposure is ubiquitous and higher phthalate metabolite concentrations documented in patients using medications with ...
Chambers, Christina, Foster, Warren G, Kay, Vanessa R   +2 more
core   +1 more source

Systematic drug sensitivity testing reveals synergistic growth inhibition by dasatinib or mTOR inhibitors with paclitaxel in ovarian granulosa cell tumor cells [PDF]

, 2017
Objective. Resistance to standard chemotherapy poses a major clinical problem in the treatment of ovarian cancer patients. Adult-type granulosa cell tumor (AGCT) is a unique ovarian cancer subtype for which efficient treatment options are lacking in ...
Aittokallio, Tero, Andersson, Noora, Anttonen, Mikko, Butzow, Ralf, Farkkila, Anniina, Haltia, Ulla-Maija, Heikinheimo, Markku, Kallioniemi, Olli, Kankainen, Matti, Kulesskiy, Evgeny, Leminen, Arto, Riska, Annika, Tang, Jing, Unkila-Kallio, Leila, Wennerberg, Krister, Yadav, Bhagwan   +15 more
core   +1 more source

Adult‐Onset Juvenile Granulosa Cell Tumor With Early Metastasis: A Rare Case With Fatal Outcome

Case Reports in Obstetrics and Gynecology, Volume 2026, Issue 1, 2026.
Background Juvenile granulosa cell tumors (JGCTs) are rare ovarian sex cord–stromal tumors that primarily affect children and adolescents. Their occurrence in adults is exceptionally uncommon and presents unique diagnostic and therapeutic challenges due to limited evidence.
Zainab Chatbi, Ghizlane Graiti, Hafsa Taheri, Hanane Saadi, Ahmed Mimouni, Suraiya Saleem   +5 more
wiley   +1 more source

The molecular mechanism of ovarian granulosa cell tumors

Journal of Ovarian Research, 2018
Over these years, more and more sex cord-stromal tumors have been reported. Granulosa cell tumor (GCT) is a rare tumor in ovaries, accounts for 2% to 5% of ovarian cancers.
Jiaheng Li, Riqiang Bao, Shiwei Peng, Chunping Zhang   +3 more
doaj   +1 more source

Estrone and estradiol concentrations in human ovaries, testes, and adrenals during the first two years of life [PDF]

, 1987
To determine the origin of estrogens in infant blood, we measured estrone (E1) and estradiol (E2) in the gonads of 50 girls and 64 boys who died suddenly between birth and 2 yr of age as well as in the adrenals of 18 of these infant girls and 16 of the ...
Bidlingmaier, F., Dorr, H. G., Eisenmenger, Wolfgang, Knorr, D., Strom, T. M.   +4 more
core   +1 more source

A Rare Case of Nasal Chondromesenchymal Hamartoma Presenting With Respiratory Distress in a Newborn: A Case Report

Case Reports in Otolaryngology, Volume 2026, Issue 1, 2026.
Introduction Nasal chondromesenchymal hamartoma (NCMH) is a rare cause of nasal mass in infants and children. It was first described in 1998, and since then, only 63 previous cases have been reported. Case Report Here, we report a case of a 4‐day‐old neonate with a right‐sided nasal mass presenting with respiratory distress since birth.
Mikiyas Olani, Mohammed Juhar, Siraw Girum, Amanuel Damie, Alemwork Amare, Abel Daniel, Gabriella Cadoni   +6 more
wiley   +1 more source

Surgical Management of Ovarian Masses in Children: A Comparative Analysis by Pediatric Surgeons and Gynecologists at Two Academic Hospitals in Johannesburg

Cancer Reports, Volume 8, Issue 11, November 2025.
ABSTRACT Background and Objectives Existing literature on ovarian masses necessitating intervention in children by pediatric surgeons and gynecologists in Low‐ and Middle‐Income Countries is sparse and lacks collaborative standardization in management between the two subspecialties.
Nkhensani C. Mashaba, Langanani Mbodi, Ellen M. Mapunda, Tanvier Omar, Derek S. Harrison   +4 more
wiley   +1 more source

Tracing metastatic spread in pediatric solid tumors using copy number and targeted deep sequencing

The Journal of Pathology, Volume 267, Issue 3, Page 347-365, November 2025.
Abstract The most common cause of death in pediatric cancer patients is a treatment‐resistant tumor, compounded by metastatic spread, making surgery, radiation therapy, and chemotherapy unfeasible as curative treatment options. However, the mechanisms behind metastatic spread in pediatric tumors remain largely unexplored. We conducted whole‐genome copy
Natalie Andersson, Michele Ferro, Caroline Jansson, Subhayan Chattopadhyay, Jenny Karlsson, David Gisselsson   +5 more
wiley   +1 more source

Immunohistochemical markers of prognosis in adult granulosa cell tumors of the ovary – a review

Journal of Ovarian Research, 2023
Background Granulosa cell tumors (GCT) are rare malignant ovarian tumors. The two subtypes, adult and juvenile granulosa cell tumors, differ in clinical and molecular characteristics.
Dennis Jung, Katrin Almstedt, Marco J. Battista, Alexander Seeger, Jörg Jäkel, Walburgis Brenner, Annette Hasenburg   +6 more
doaj   +1 more source