Folate receptor alpha (FRα) expression in tubo‐ovarian and endometrial tumors: a study of 923 cases
Abstract Folate receptor alpha (FRα) is a promising therapeutic target due to its high expression in several tumor types and its rare expression in healthy tissue. Recently, the antibody‐drug conjugate mirvetuximab soravtansine has been approved for treatment of advanced platinum‐resistant high‐grade serous carcinoma (HGSC).
Isabela Töltési +13 more
wiley +1 more source
Assessment of twenty testicular AGCTs with two different next‐generation sequencing (NGS) panels reveals differences with ovarian AGCTs, including absence of hotspot FOXL2 variants. Aims Testicular adult granulosa cell tumours (AGCTs) are rare and show several clinical–pathological differences with their ovarian counterparts.
Costantino Ricci +20 more
wiley +1 more source
Larval and early juvenile development of Paralomis granulosa reared at different temperatures: tolerance of cold and food limitation in a lithodid crab from high latitudes [PDF]
Paralomis granulosa Jacquinot is a commercially fished lithodid crab species living in subantarctic and cold-temperate regions of southern South America.
Lovrich, G. +7 more
core +1 more source
Juvenile Granulosa Cell Tumor with Elevated Peripheral Interleukin-6 Level Shows Prolonged Fever and Delayed Puberty [PDF]
Juvenile granulosa cell tumor (JGCT), classified as a sex cord-stromal tumor, is a rare neoplasm. This is an instructive case report of JGCT accompanied by augmented interleukin (IL)-6 secretion.
17268 +29 more
core +1 more source
Personalized Models of Biological Barriers and Their Diseases: Recent Progress with Organs‐On‐Chips
Buck and Bugter et al. explore the architectural diversity and physiological functions of human barrier systems and reveal how organ‐on‐chip platforms, particularly those integrating patient‐derived cells, are advancing barrier disease modeling. They highlight how emerging biological and technological advances can be used to bridge the gap between ...
Franziska Buck +4 more
wiley +1 more source
Immunohistochemical markers of prognosis in adult granulosa cell tumors of the ovary – a review
Background Granulosa cell tumors (GCT) are rare malignant ovarian tumors. The two subtypes, adult and juvenile granulosa cell tumors, differ in clinical and molecular characteristics.
Dennis Jung +6 more
doaj +1 more source
Adult‐Onset Juvenile Granulosa Cell Tumor With Early Metastasis: A Rare Case With Fatal Outcome
Background Juvenile granulosa cell tumors (JGCTs) are rare ovarian sex cord–stromal tumors that primarily affect children and adolescents. Their occurrence in adults is exceptionally uncommon and presents unique diagnostic and therapeutic challenges due to limited evidence.
Zainab Chatbi +5 more
wiley +1 more source
ANTECEDENTES: El tumor de células de la granulosa representa del 2 al 5% de las neoplasias del ovario. Su manifestación clínica no siempre es específica.
Sillero Castillo, Ana +2 more
core +1 more source
Introduction Nasal chondromesenchymal hamartoma (NCMH) is a rare cause of nasal mass in infants and children. It was first described in 1998, and since then, only 63 previous cases have been reported. Case Report Here, we report a case of a 4‐day‐old neonate with a right‐sided nasal mass presenting with respiratory distress since birth.
Mikiyas Olani +6 more
wiley +1 more source
Extraovarian juvenile granulosa cell tumor in a prepubertal child: novel location of a rare tumor
Juvenile granulosa cell tumor (JGCT) is the most common type of sex cord stromal tumor arising from gonadal structures of children and young adults.
ORHAN, DİCLEHAN +6 more
core +1 more source

