Rapidly growing juvenile granulosa cell tumor of the ovary arising in adult: a case report and review of the literature [PDF]
Background Ovarian granulosa cell tumors (GCTs) are divided into adult GCT (AGCT) and juvenile GCT (JGCT). The AGCT is more common type, conversely, less than 5% of tumors are the JGCT and occur in mainly premenarchal girls and in women younger than 30 ...
Yuki Inada +7 more
doaj +2 more sources
Objective: Ovarian juvenile granulosa cell tumor has an interesting association with multiple enchondromatosis (Ollier disease and Maffucci syndrome) and should be considered a leading diagnosis when an ovarian mass is found in young patients with these ...
Andrea Burgetova +8 more
doaj +3 more sources
Juvenile Granulosa Cell Tumor of the Testis: Prenatal Diagnosis and Management [PDF]
Prepubertal primary testicular tumors account for ∼1% of all pediatric solid tumors. We report a new case of prenatal diagnosis of juvenile-type granulosa cell tumor (JGCT).
Fabrizio Vatta +6 more
doaj +2 more sources
Juvenile Granulosa Cell Tumor of the Ovary in Pregnancy: A Case Report [PDF]
Juvenile-type granulosa cell tumors (JGCT) of the ovary are extremely rare. Most of them occur in premenarchal girls. The occurrence of JGCT in an adult, particularly during pregnancy, is very rare.
Kavita Khoiwal +5 more
doaj +2 more sources
Juvenile Granulosa Cell Tumor Mimicking HAIR-AN in a 4-year-old: A Case Report [PDF]
Predominantly androgen secreting juvenile granulosa cell tumors (JGCT) are uncommon and few reports have been published. We present a case of a JGCT that presented with signs of prepubertal hyperandrogenism and insulin resistance to highlight the ...
Rachel Choe Kim +6 more
doaj +2 more sources
Advances in non-germ cell tumours of the testis: focus on new molecular developments in sex cord-stromal tumours. [PDF]
In this review, we summarise the major recent advances in Testicular Sex Cord‐Stromal Tumours, focusing on molecular alterations and biomarkers relevant for diagnosis, classification and prognosis. Testicular sex cord‐stromal tumours (TSCSTs) represent ~4%–8% of all testicular neoplasms.
Lobo J, Acosta AM.
europepmc +2 more sources
Adult granulosa cell tumours of the testis analogous to ovarian counterparts are exceptionally rare: analysis of a multicentric series and review of the literature. [PDF]
Assessment of twenty testicular AGCTs with two different next‐generation sequencing (NGS) panels reveals differences with ovarian AGCTs, including absence of hotspot FOXL2 variants. Aims Testicular adult granulosa cell tumours (AGCTs) are rare and show several clinical–pathological differences with their ovarian counterparts.
Ricci C +20 more
europepmc +2 more sources
Folate receptor alpha (FRα) expression in tubo-ovarian and endometrial tumors: a study of 923 cases. [PDF]
Abstract Folate receptor alpha (FRα) is a promising therapeutic target due to its high expression in several tumor types and its rare expression in healthy tissue. Recently, the antibody‐drug conjugate mirvetuximab soravtansine has been approved for treatment of advanced platinum‐resistant high‐grade serous carcinoma (HGSC).
Töltési I +13 more
europepmc +2 more sources
Juvenile Granulosa Cell Tumor of the Testis: A Preoperative Approach of the Diagnosis with Ultrasound [PDF]
Granulosa cell tumor of the testis is a rare intermediate stromal cell tumor that can be distinguished in adult and juvenile type. The juvenile type is commonly presented in infants less than a year old-most often during the first 6 months of life and ...
Rodanthi Sfakiotaki, MS, Sergia Liasi, BM, Eleni Papaiakovou, BM, Irene Vraka, PhD, Marina Vakaki, PhD, Chrysoula Koumanidou, PhD
doaj +1 more source
A Case Report of Anaplastic Variant Juvenile Granulosa Cell Tumour [PDF]
Introduction: Anaplastic variant of juvenile granulosa cell tumor is one of the rarest ovarian malignancies. The aim of this study is to describe a case of anaplastic variant ovarian granulosa cell tumor in a 14-year-old girl with presentation of ...
Masoumeh Gharib +3 more
doaj +1 more source

