Results 21 to 30 of about 3,652 (213)

Ovarian juvenile granulosa cell tumors with Ollier’s disease in children with IDH1 gene somatic mutation

Frontiers in Endocrinology, 2023
ObjectiveThe aim of this study was to explore the symptoms, treatment, and pathogenesis of ovarian juvenile granulosa cell tumors with Ollier’s disease in children.MethodsFrom October 2019 to October 2020, clinical data were retrospectively analyzed for ...
Jin Zhang, Renwu Hua, Lishuang Ma, Chao Liu, Yanxia Zhang, Xuemin Lü, Tianren Wang, Naijun Wan   +7 more
doaj   +1 more source

Adult granulosa cell tumours of the testis analogous to ovarian counterparts are exceptionally rare: analysis of a multicentric series and review of the literature. [PDF]

Histopathology
Assessment of twenty testicular AGCTs with two different next‐generation sequencing (NGS) panels reveals differences with ovarian AGCTs, including absence of hotspot FOXL2 variants. Aims Testicular adult granulosa cell tumours (AGCTs) are rare and show several clinical–pathological differences with their ovarian counterparts.
Ricci C, de Biase D, Maloberti T, Orsatti A, Ulbright TM, Idrees MT, Oliva E, Cornejo K, Lobo J, Michalova K, Raspollini MR, Williamson SR, van Leenders GJ, Kao CS, Maclean F, Sangoi AR, Osunkoya AO, Fiorentino M, De Leo A, Tallini G, Acosta AM.   +20 more
europepmc   +2 more sources

Folate receptor alpha (FRα) expression in tubo-ovarian and endometrial tumors: a study of 923 cases. [PDF]

J Pathol Clin Res
Abstract Folate receptor alpha (FRα) is a promising therapeutic target due to its high expression in several tumor types and its rare expression in healthy tissue. Recently, the antibody‐drug conjugate mirvetuximab soravtansine has been approved for treatment of advanced platinum‐resistant high‐grade serous carcinoma (HGSC).
Töltési I, Němejcová K, Kendall Bártů M, Vránková R, Cibula D, Fabian P, Frühauf F, Hausnerová J, Laco J, Méhes G, Špůrková Z, Švajdler M, Matěj R, Dundr P.   +13 more
europepmc   +2 more sources

Juvenile granulosa cell tumor in a nine year old

Journal of Pediatric Surgery Case Reports, 2020
Pediatric granulosa cell tumors of the ovary are rare functional neoplasms causing secondary precocious puberty. The tumor possesses significant diagnostic challenge when occurs in a patient approaching puberty due to masking of symptoms.
Syed Waqas Ali, Nouman Nawaz Ali, M. Sajjad Ashraf, Muhammad Arif Mateen Khan, Muhammad Usman Tariq   +4 more
doaj   +1 more source

Constitutively active transforming growth factor β receptor 1 in the mouse ovary promotes tumorigenesis [PDF]

, 2016
Despite the well-established tumor suppressive role of TGFβ proteins, depletion of key TGFβ signaling components in the mouse ovary does not induce a growth advantage.
Bartholin, Laurent, Davis, Anna Jane, Gao, Yang, Li, Qinglei, Sansom, Owen, Vincent, David   +5 more
core   +1 more source

Molecular manipulation of keratin 8/18 intermediate filaments: modulators of FAS-mediated death signaling in human ovarian granulosa tumor cells [PDF]

, 2016
Background: Granulosa cell tumors (GCT) are a rare ovarian neoplasm but prognosis is poor following recurrence. Keratin intermediate filaments expressed in these tumors are a diagnostic marker, yet paradoxically, may also constitute a target for ...
Davis, John S., Hou, Xiaoying, Schwab, Nicolette M., Townson, David H., Trisdale, Sarah K.   +4 more
core   +3 more sources

Juvenile granulosa cell tumor: A rare case of hemoperitoneum in a 5-month-old infant

Journal of Pediatric Surgery Case Reports, 2020
This is a case with associated radiologic and intra-operative images for an infant who presented with hemoperitoneum and acute abdomen. Pre-operative imaging included abdominal ultrasound and computed tomography, which raised suspicion for a pelvic mass ...
Centura R. Anbarasu, Lily S. Cheng, Bindi Naik-Mathuria, Mark V. Mazziotti   +3 more
doaj   +1 more source

Juvenile Type Granulosa Cell Tumor

Serbian Journal of Experimental and Clinical Research, 2018
Abstract Granulosa cell tumor is a type of neoplasm, which represents 2-5% of all ovarian cancers. About 5% of these tumors are juvenile- type and usually occur to girls before puberty and to women younger than thirty years of age. There are signs premature puberty or premature emergence of secondary sexual characteristics with irregular
Andric B., Arsenijevic P., Jović N., Arsenijevic, Nebojsa, Protrka, Zoran   +4 more
openaire   +2 more sources

Juvenile Granulosa Cell Tumors of the Testis: A Clinicopathologic Study of 70 Cases with Emphasis on Its Wide Morphologic Spectrum [PDF]

, 2015
The clinical and pathologic features of 70 juvenile granulosa cell tumors (JGCTs) of the testis are presented. The patients were from 30 weeks gestational age to 10 years old; 60 of 67 (90%) whose ages are known to us were 6 months old or younger.
Cornejo, Kristine M., Kao, Chia-Sui, Ulbright, Thomas M., Young, Robert H.   +3 more
core   +1 more source

Prevalence and Management of Nonepithelial Ovarian Cancer in a Sub-Saharan African Setting. [PDF]

Obstet Gynecol Int
Background Nonepithelial ovarian cancers (NEOCs) comprise a group of uncommon malignancies which can be challenging to treat. This broad term includes germ cell tumors, sex cord–stromal tumors, and rare types of ovarian cancer, such as small‐cell carcinomas and sarcomas.
Batu BG, Wondafrash M, Teka AY, Lucero-Prisno DE, Sium AF.   +4 more
europepmc   +2 more sources