Juvenile Granulosa Cell Tumors of the Ovary
Abstract Objective To explore the clinical and pathologic features of ovarian juvenile granulosa cell tumors (JGCTs). Methods Clinical data, histopathologic observations, immunohistochemical results, FOXL2 mutation status, and follow ...
Yuhong Ye +6 more
openaire +2 more sources
Advances in non-germ cell tumours of the testis: focus on new molecular developments in sex cord-stromal tumours. [PDF]
In this review, we summarise the major recent advances in Testicular Sex Cord‐Stromal Tumours, focusing on molecular alterations and biomarkers relevant for diagnosis, classification and prognosis. Testicular sex cord‐stromal tumours (TSCSTs) represent ~4%–8% of all testicular neoplasms.
Lobo J, Acosta AM.
europepmc +2 more sources
Juvenile granulosa cell tumor in a nine year old
Pediatric granulosa cell tumors of the ovary are rare functional neoplasms causing secondary precocious puberty. The tumor possesses significant diagnostic challenge when occurs in a patient approaching puberty due to masking of symptoms.
Syed Waqas Ali +4 more
doaj +1 more source
Juvenile granulosa cell tumor: A rare case of hemoperitoneum in a 5-month-old infant
This is a case with associated radiologic and intra-operative images for an infant who presented with hemoperitoneum and acute abdomen. Pre-operative imaging included abdominal ultrasound and computed tomography, which raised suspicion for a pelvic mass ...
Centura R. Anbarasu +3 more
doaj +1 more source
Adult granulosa cell tumours of the testis analogous to ovarian counterparts are exceptionally rare: analysis of a multicentric series and review of the literature. [PDF]
Assessment of twenty testicular AGCTs with two different next‐generation sequencing (NGS) panels reveals differences with ovarian AGCTs, including absence of hotspot FOXL2 variants. Aims Testicular adult granulosa cell tumours (AGCTs) are rare and show several clinical–pathological differences with their ovarian counterparts.
Ricci C +20 more
europepmc +2 more sources
Folate receptor alpha (FRα) expression in tubo-ovarian and endometrial tumors: a study of 923 cases. [PDF]
Abstract Folate receptor alpha (FRα) is a promising therapeutic target due to its high expression in several tumor types and its rare expression in healthy tissue. Recently, the antibody‐drug conjugate mirvetuximab soravtansine has been approved for treatment of advanced platinum‐resistant high‐grade serous carcinoma (HGSC).
Töltési I +13 more
europepmc +2 more sources
A rare ovarian tumor in childhood: Juvenile granulosa cell tumor revealed by pelvic pain and ovarian torsion. [PDF]
We report the case of a 5-year-old girl admitted with a one-month history of pelvic heaviness and acute pelvic pain. Imaging revealed a large heterogeneous pelvic mass involving the genital compartment, with features suggestive of a malignant ovarian ...
Haddar K +6 more
europepmc +2 more sources
Ovarian Juvenile Granulosa Cell Tumor Case Report [PDF]
N ...
Lemmons, Jasmine +2 more
openaire +4 more sources
Adult-Type Granulosa Cell Tumor of the Testis: A Report of a Case and a Discussion of the Literature
Testicular granulosa cell tumors (TGCTs) are rare tumors of sex cord-stromal origin. TGCTs are classified into two main categories, the adult type and the juvenile type.
Georgios Zervopoulos +3 more
doaj +1 more source
Prevalence and Management of Nonepithelial Ovarian Cancer in a Sub-Saharan African Setting. [PDF]
Background Nonepithelial ovarian cancers (NEOCs) comprise a group of uncommon malignancies which can be challenging to treat. This broad term includes germ cell tumors, sex cord–stromal tumors, and rare types of ovarian cancer, such as small‐cell carcinomas and sarcomas.
Batu BG +4 more
europepmc +2 more sources

