Results 51 to 60 of about 5,067,029 (185)

Factor analysis of the hospital anxiety and depression scale among a Huntington's disease population

, 2015
Introduction: Depression and anxiety are common in Huntington's disease, a genetic neurodegenerative disorder. There is a need for measurement tools of mood to be validated within a Huntington's disease population.
ROMANO, SILVIA, Shimozaki, Steve, Maltby, John, Martucci, Rossana, Registry, investigators of theEuropean Huntington's Disease Network, Dale, Maria   +5 more
core   +1 more source

Avoidance as a strategy of (not) coping: qualitative interviews with carers of Huntington's Disease patients [PDF]

, 2005
Peer ...
Lowit, Alison, van Teijlingen, Edwin R.
core   +4 more sources

Radiotherapy Side Effects: Comprehensive Proteomic Study Unraveled Neural Stem Cell Degenerative Differentiation upon Ionizing Radiation

Biomolecules, 2022
Cranial radiation therapy is one of the most effective treatments for childhood brain cancers. Despite the ameliorated survival rate of juvenile patients, radiation exposure-induced brain neurogenic region injury could markedly impair patients’ cognitive
Dong Liang, Meng Ning, Hang Xie, Xiaoyan He, Peigen Ren, Xiaohua Lei, Xuepei Zhang   +6 more
doaj   +1 more source

The Timely Rise of a Teenage Reformer: Youth Revolt, Feminism and the Struggle for a ‘New Sexual Morality’ at the Dawn of the Spanish Second Republic

Gender &History, EarlyView.
ABSTRACT The contributions of propagandist and writer Hildegart (1914–1933) to Spanish cultural life are overshadowed by accounts of her unusual upbringing and violent death. This article examines the conditions that enabled the teenager to become a prominent voice for feminism and sexual reform on the eve of Spain's Second Republic (1931–1939).
Micaela Pattison
wiley   +1 more source

Analysis of White Adipose Tissue Gene Expression Reveals CREB1 Pathway Altered in Huntington's Disease. [PDF]

, 2015
In addition to classical neurological symptoms, Huntington's disease (HD) is complicated by peripheral pathology and both the mutant gene and the protein are found in cells and tissues throughout the body.
Haider, Salman, Björkqvist, Maria, Tabrizi, Sarah J, Silajdzic, Edina, Sethi, Huma,, Parker, Jennifer, McCourt, Andy, Björkqvist, Maria,, McCourt, Andy,, Haider, Salman,, Silajdzic, Edina,, Tabrizi, Sarah J,, Warner, Thomas T,, Parker, Jennifer,, Warner, Thomas T, Lund University., Sethi, Huma   +16 more
core   +1 more source

Ghosts From the Past: A Juvenile Onset Huntington's Disease Case From Bahrain

BJPsych Open
Aims Huntington’s disease (HD) is a rare inherited disease in an autosomal dominant pattern, that is most prevalent among Caucasians. Juvenile onset Huntington disease (JHD) is a rare subtype of the disease, defined by presence of the disease by the age
Hanan Husain, Shaima Bucheeri, Feras Alsaif   +2 more
doaj   +1 more source

Genetic epidemiological characteristics of a Hungarian subpopulation of patients with Huntington’s disease

BMC Neurology, 2021
Background Recent advances in therapeutic options may prevent deterioration related to Huntington’s disease (HD), even at the pre-symptomatic stage. Be that as it may, a well-characterized patient population is essential for screening and monitoring ...
Katalin Despotov, Dénes Zádori, Gábor Veres, Katalin Jakab, Gabriella Gárdián, Eszter Tóth, Tamás Zsigmond Kincses, László Vécsei, András Ajtay, Dániel Bereczki, Péter Klivényi   +10 more
doaj   +1 more source

Iloperidone treatment mitigates the Juvenile Huntington's Disease phenotype possibly via Sigma‐1 Receptor Modulation

The FEBS Journal, EarlyView.
We investigated the potential of iloperidone as an activator of Sigma‐1 receptor (S1R) neuroprotective function in juvenile Huntington's disease (jHD). We tested iloperidone on cortical neurons differentiated from patient‐derived iPSCs, demonstrating that it acts as a S1R agonist, decreasing apoptosis, huntingtin aggregation, and oxidative stress ...
Ersilia Fornetti, Gaia Galluzzi, Mario Frezzini, Cécile Exertier, Vittorio Brufani, Gianni Colotti, Giancarlo Ruocco, Jessica Rosati, Angelo Luigi Vescovi, Daniele Narzi, Ilaria Genovese, Andrea Ilari   +11 more
wiley   +1 more source

Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells. [PDF]

PLoS ONE, 2016
Mutations of the huntingtin protein (HTT) gene underlie both adult-onset and juvenile forms of Huntington's disease (HD). HTT modulates mitotic spindle orientation and cell fate in mouse cortical progenitors from the ventricular zone.
Carla Lopes, Sophie Aubert, Fany Bourgois-Rocha, Monia Barnat, Ana Cristina Rego, Nicole Déglon, Anselme L Perrier, Sandrine Humbert   +7 more
doaj   +1 more source

Evaluation of an open formula reference diet on California yellowtail (Seriola dorsalis) Broodstock

Journal of the World Aquaculture Society, Volume 57, Issue 5, October 2026.
Abstract The reliable production of marine finfish is contingent on the quantity and quality of the eggs available from the broodstock. Proper broodstock nutrition is critical for maintaining a supply of good quality eggs. Here, we compared an open‐formula reference diet (OFRD; 18 mm pellet) and a commercial broodstock diet (Europa, Skretting; 12 mm ...
Kevin Stuart, Lee A. Fuiman, Mark Drawbridge   +2 more
wiley   +1 more source