Results 71 to 80 of about 2,427 (143)
GluN3A promotes NMDA spiking by enhancing synaptic transmission in Huntington's disease models
Neurobiology of Disease, 2016 Age-inappropriate expression of juvenile NMDA receptors (NMDARs) containing GluN3A subunits has been linked to synapse loss and death of spiny projection neurons of the striatum (SPNs) in Huntington's disease (HD).
Kashif Mahfooz +5 more
doaj +1 more source
Huntington's disease: a clinical review
Orphanet Journal of Rare Diseases, 2010 Huntington disease (HD) is a rare neurodegenerative disorder of the central nervous system characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia.
Roos Raymund AC
doaj +1 more source
Clinical and genetic study of a juvenile⁃onset Huntington disease
Chinese Journal of Contemporary Neurology and Neurosurgery, 2012 Background Huntington's disease (HD) is an autosomal dominant hereditary progressive neurodegenerative disorder with a distinct phenotype characterized by chorea, dementia, cognitive and affective impairment.
Ying HAO +8 more
doaj
A Case Report of Response to Quetiapine Treatment in Neuropsychiatric Manifestations of Juvenile Huntington\'s Disease (JHD) [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i BābulBackground and Objective: Juvenile Huntington’s disease (JHD) represents a rare form of neurodegenerative genetic disorder characterized by potential neuropsychiatric symptoms.
TMS Tengku Kamarulbahri, F Rahim
doaj
Drug-Resistant Epilepsy in Children with Juvenile Huntington's Disease: A Challenging Case and Brief Review. [PDF]
Qatar Med J, 2020 Khair Md AM, Kabrt DO J, Falchek Md S.
europepmc +1 more source
The MicrobeThe CRISPR-Cas systems, initially identified as bacterial defense mechanisms, have become innovative tools for genetic research and translational therapeutics. These systems are made up of clustered regularly interspaced short palindromic repeats (CRISPR)
Kamran Saeed +3 more
doaj +1 more source