GluN3A promotes NMDA spiking by enhancing synaptic transmission in Huntington's disease models
Neurobiology of Disease, 2016 Age-inappropriate expression of juvenile NMDA receptors (NMDARs) containing GluN3A subunits has been linked to synapse loss and death of spiny projection neurons of the striatum (SPNs) in Huntington's disease (HD).
Kashif Mahfooz +5 more
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Behavioral Genetics Research and Criminal DNA Databases [PDF]
, 2006 Kaye discusses DNA databanks and the potential use of such databanks for behavioral genetics research. He addresses the concern that DNA databanks serve as a limitless repository for future research and that the samples used in the databanks could be ...
Kaye, D. H.
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Huntington's disease: a clinical review
Orphanet Journal of Rare Diseases, 2010 Huntington disease (HD) is a rare neurodegenerative disorder of the central nervous system characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia.
Roos Raymund AC
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Evaluating motor progression of juvenile-onset Huntington's Disease: An Enroll-HD analysis [PDF]
, 2023 Sophia Nopoulos +4 more
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Clinical and genetic study of a juvenile⁃onset Huntington disease
Chinese Journal of Contemporary Neurology and Neurosurgery, 2012 Background Huntington's disease (HD) is an autosomal dominant hereditary progressive neurodegenerative disorder with a distinct phenotype characterized by chorea, dementia, cognitive and affective impairment.
Ying HAO +8 more
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Potential Neuroprotective Drug Evp4593 Reduces Excessive Expression of Huntingtin in iPSC-Based Juvenile Model of Huntington's Disease [PDF]
, 2019 Dmitry Grekhnyov +2 more
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Diverse Mechanisms of Trinucleotide Repeat Disorders: An Exploration of Fragile X Syndrome and Huntington’s Disease [PDF]
, 2013 Trinucleotide repeat disorders are an umbrella group of genetic diseases that have been well described clinically for a long time; however, the scientific community is only beginning to understand their molecular basis.
Strobel, Cara
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Neuropsychological functioning in juvenile/adolescent onset Huntington's disease: A case series [PDF]
, 1997 J. J. Vasterling +4 more
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Longitudinal Clinical and Biological Characteristics in Juvenile‐Onset Huntington's Disease
, 2022 Jordan L. Schultz +10 more
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A Case Report of Response to Quetiapine Treatment in Neuropsychiatric Manifestations of Juvenile Huntington\'s Disease (JHD) [PDF]
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i BābulBackground and Objective: Juvenile Huntington’s disease (JHD) represents a rare form of neurodegenerative genetic disorder characterized by potential neuropsychiatric symptoms.
TMS Tengku Kamarulbahri, F Rahim
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