Results 121 to 130 of about 53,788 (241)
CANAKINUMAB IN THE TREATMENT OF RHEUMATIC DISEASES IN CHILDREN
Вопросы современной педиатрии, 2014 The article describes international multicenter controlled studies of efficacy and safety of monoclonal antibodies towards interleukin 1β — kanakinumab — when treating cryopyrin-associated periodic syndrome and systemic juvenile idiopathic arthritis in ...
Ye. I. Alekseeva, R. V. Denisova
doaj +1 more source
Juvenile arthritis caused by a novel FAMIN (LACC1) mutation in two children with systemic and extended oligoarticular course [PDF]
, 2016 Background The pathophysiological origin of juvenile idiopathic arthritis (JIA) is largely unknown. However, individuals with presumably pathogenic mutations in FAMIN have been reported, associating this gene with a rare subtype of this disorder.
Hundsdoerfer, Patrick +7 more
core +1 more source
Journal of Diabetes Investigation, EarlyView.In this target trial emulation of patients with immune‐mediated inflammatory diseases and type 2 diabetes, SGLT2 inhibitor initiation was not associated with a clear increase in UTI risk versus metformin, including across immunosuppressive therapy strata.
Hiroshi Tsushima +6 more
wiley +1 more source
Blogging as a viable research methodology for young people with arthritis: a qualitative study. [PDF]
, 2015 The development of services that are responsive to the needs of users is a health policy priority. Finding ways of engaging young people in research to gain insights into their particular experiences, perspectives, and needs is vital but challenging ...
Gray, NJ +3 more
core
Clinical phenotypes and biologic treatment use in juvenile dermatomyositis-associated calcinosis [PDF]
, 2018 Background Few risk factors have been identified for the development of calcinosis among patients with Juvenile Dermatomyositis, and currently no clinical phenotype has been associated with its development.
Al-Hammadi, Noor +4 more
core +2 more sources
Myeloid A20 Regulates Periodontal Tissue Integrity and Temporomandibular Joint Structure
Journal of Periodontal Research, EarlyView.Dysregulation of A20 signaling has been implicated in several immune‐mediated diseases, including rheumatoid arthritis and psoriasis, conditions characterized by excessive NF‐κB activation and inflammatory tissue damage. The structural alterations observed in this model suggest that impaired regulation of innate immune signaling may increase ...
Karol Alí Apaza Alccayhuaman +6 more
wiley +1 more source
Oral Diseases, EarlyView.ABSTRACT Objective This systematic review and meta‐analysis aimed to evaluate the most effective minimally invasive intra‐articular procedure for reducing pain and improving maximum mouth opening (MMO) in individuals diagnosed with painful articular TMD, specifically TMJ osteoarthritis and/or internal derangement.
Mateus Gaya dos Santos +5 more
wiley +1 more source
Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang +3 more
wiley +1 more source
A Teenage Guitarist's Swollen Fingers
JEADV Clinical Practice, EarlyView.
Maho Matsuo, Hiroaki Iwata
wiley +1 more source
Tubulointerstitial nephritis and uveitis syndrome in children: What to keep an eye on
Acta Ophthalmologica, Volume 104, Issue 4, Page e443-e452, June 2026.Abstract Purpose The purpose of this study was to determine the disease course in patients with tubulointerstitial nephritis and uveitis (TINU) syndrome, focusing on long‐term outcome and the incidence of complications such as chronic kidney disease (CKD).
Jytte Hendrikse +4 more
wiley +1 more source