Results 131 to 140 of about 93,672 (307)
Development and Role in Therapy of Canakinumab in Adult-Onset Still's Disease [PDF]
, 2018 Adult-onset Still's disease (AOSD) is a rare inflammatory disease of unknown etiology typically characterized by episodes of spiking fever, evanescent rash, arthralgia, leukocytosis, and hyperferritinemia. The pivotal role of interleukin (IL)-1 and other
Baggio, Chiara +4 more
core +1 more source
Severe Systemic Juvenile Idiopathic Arthritis-Associated Lung Disease in a Puerto Rican Child [PDF]
, 2021 V. Ocasio +2 more
openalex +1 more source
IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak +7 more
wiley +1 more source
CANAKINUMAB IN THE TREATMENT OF RHEUMATIC DISEASES IN CHILDREN
Вопросы современной педиатрии, 2014 The article describes international multicenter controlled studies of efficacy and safety of monoclonal antibodies towards interleukin 1β — kanakinumab — when treating cryopyrin-associated periodic syndrome and systemic juvenile idiopathic arthritis in ...
Ye. I. Alekseeva, R. V. Denisova
doaj +1 more source
Aging Cell, EarlyView.Combined baricitinib and lonafarnib treatment improved colonic pathology in LmnaG609G/G609G progeria mice by reducing progerin, maintaining epithelial regeneration, mitigating inflammation and senescence, and preserving microbiome composition. ABSTRACT Hutchinson‐Gilford Progeria Syndrome (HGPS) is a fatal genetic disorder caused by progerin, a mutant ...
Moritz Schroll +4 more
wiley +1 more source
Pediatric Rheumatology Online Journal, 2018 BackgroundConventional pharmacological therapies for the treatment of juvenile idiopathic arthritis (JIA) consist of non-biological, disease-modifying antirheumatic drugs, among which methotrexate (MTX) is the most commonly prescribed.
G. Ferrara +9 more
semanticscholar +1 more source
Disease activity states, reasons for discontinuation and adverse events in 1038 Italian children with juvenile idiopathic arthritis treated with etanercept [PDF]
, 2017 The advent of biologic medications has increased considerably the potential for treatment benefit in juvenile idiopathic arthritis (JIA), with clinical remission being now achievable in a substantial proportion of patients.
A. Civino +27 more
core
TREATMENT APPROACH FOR JUVENILE IDIOPATHIC ARTHRITIS-RELATED UVEITIS: 2012 UPDATE
Вопросы современной педиатрии, 2012 Chronic anterior uveitis is the most common extra-articular complication of juvenile idiopathic arthritis. It is more frequent in the early onset forms with a higher prevalence in the oligoarticular (40%) than in other juvenile idiopathic arthritis ...
Francesco Zulian +2 more
doaj +1 more source
Biologic‐Induced Paradoxical Psoriatic Alopecia: A Systematic Review
Australasian Journal of Dermatology, EarlyView.ABSTRACT A systemic review was completed of primary research articles reporting patient outcomes in paradoxical psoriatic alopecia in association with biologic therapy. Our search strategy identified 96 patients from 45 studies in addition to our own case.
Yaron Gu +3 more
wiley +1 more source
Contemporary Clinical Dentistry, 2014 Juvenile Idiopathic Arthritis (JIA) is the most chronic musculoskeletal disease of pediatric population. The chronic course of disease has a great impact on oral health.
Krupa H Bhatt +3 more
doaj +1 more source