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Juvenile idiopathic arthritis

Autoimmunity Reviews, 2006
One of the most enigmatic problems in rheumatology has been juvenile idiopathic arthritis (JIA). Firstly, the classification has often depended on clinical features that have variations between patients. Secondly, there are different classification schemes in usage and there are few objective serologic tests that help to resolve the differences between
A. T. Borchers   +5 more
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Juvenile idiopathic arthritis

Nederlands Tijdschrift voor Tandheelkunde, 2018
Juvenile idiopathic arthritis (JIA) is the most common cause of chronic inflammation of the joints in childhood. Currently, JIA is divided into 7 subtypes, distinguished on the basis of the symptoms present in the first six months of the illness. Pharmacological treatment is different for every subtype. With all forms of JIA, dental problems can occur.
Schatorjé, E.J., Royen-Kerkhof, A. Van
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Systemic Juvenile Idiopathic Arthritis

Pediatric Clinics of North America, 2018
Systemic juvenile idiopathic arthritis (sJIA) is a distinctive subtype of juvenile idiopathic arthritis, characterized by fever and arthritis, often accompanied by rash, sometimes by generalized lymphadenopathy, hepatosplenomegaly, and serositis. The diagnosis requires adequate exclusion of infectious, oncologic, autoimmune, and autoinflammatory ...
Rayfel Schneider, Jennifer J Y Lee
exaly   +3 more sources

Juvenile Idiopathic Arthritis

Rheumatic Disease Clinics of North America, 2005
Juvenile idiopathic arthritis (JIA), a term referring to a group of disorders characterized by chronic arthritis, is the most common chronic rheumatic illness in children and is a significant cause of short- and long-term disability. This article discusses the classification, differential diagnosis, and treatment of JIA.
Jennifer E, Weiss, Norman T, Ilowite
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The Etiology of Juvenile Idiopathic Arthritis

Clinical Reviews in Allergy & Immunology, 2014
Over the years, the commonly used term to describe juvenile idiopathic arthritis (JIA) has changed. By definition, JIA includes all types of arthritis with no apparent cause, lasting more than 6 weeks, in patients aged less than 16 years at onset. JIA pathogenesis is still poorly understood: the interaction between environmental factors and multiple ...
Rigante, Donato, Bosco, A, Esposito, S.
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Adalimumab in juvenile rheumatoid arthritis/juvenile idiopathic arthritis

Expert Review of Clinical Immunology, 2008
Chronic arthritis in childhood is the most common pediatric rheumatic disease and can lead to significant short- and long-term disability. TNF-a is a cytokine involved in joint inflammation and destruction. It has been suggested that early and aggressive treatment leads to improved outcomes by ameliorating clinical signs and symptoms, inhibiting joint ...
Katherine Anne B, Marzan   +1 more
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Pharmacosurveillance in Juvenile Idiopathic Arthritis

Rheumatic Disease Clinics of North America, 2021
The advent of biologic disease-modifying antirheumatic drugs targeting specific cytokines or cell-cell interactions has dramatically changed the outlook of patients with juvenile idiopathic arthritis. However, safety concerns remain around the use of therapeutic agents for children with juvenile idiopathic arthritis.
Natalie J, Shiff, Timothy, Beukelman
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Early Juvenile Idiopathic Arthritis

Rheumatic Disease Clinics of North America, 2012
Early juvenile idiopathic arthritis (JIA) is important to recognize as timely diagnosis and treatment improves prognosis. It is a misconception that complications of JIA arise only from long-standing disease and that children will outgrow it. Early aggressive treatment is the paradigm as early disease activity has long-term consequences.
Katherine Anne B, Marzan, Bracha, Shaham
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Glucocorticoids in Juvenile Idiopathic Arthritis

Neuroimmunomodulation, 2014
Glucocorticoid (GC) drugs are a potent and rapidly effective therapeutic option for the treatment of juvenile idiopathic arthritis (JIA). These medications are mainly used for the management of the extra-articular features of systemic-onset disease. A course of low-dose prednisone may be considered for achieving a rapid disease control in patients with
Schiappapietra B   +5 more
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Imaging of Juvenile Idiopathic Arthritis

Pediatric Radiology, 2006
Over the past decade there have been considerable changes in the classification and imaging of juvenile idiopathic arthritis (JIA). Radiology now has a considerable role in the management of JIA, the differential diagnosis, monitoring disease progression and detecting complications. The different imaging modalities available, their role and limitations
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