Exhaustion‐Resistant CD8 + T Cells in Ankylosing Spondylitis: A Proposed Three‐Axis Model
Exhaustion‐resistant CD8+ T cells may sustain ankylosing spondylitis. A three‐axis model—intermittent T‐cell receptor engagement, IL‐15/CD28 co‐stimulation and maintained metabolic fitness—explains how PD‐1^high CD8+ T cells retain effector function and accumulate from gut to entheses, promoting inflammation and aberrant bone remodelling.
Xuhong Zhang +3 more
wiley +1 more source
Transfer of Aging: Implications for Pediatric Solid Organ Transplantation
ABSTRACT Solid organ transplantation (SOT) is a life‐saving intervention for pediatric patients with end‐stage organ failure. Due to the limited availability of pediatric donor organs, organs from older donors are frequently utilized, increasing the risk of age‐mismatched transplants.
Rosalie Wolff von Gudenberg +14 more
wiley +1 more source
Using the attract method to identify core pathways in juvenile idiopathic arthritis
Jiashuo Li +3 more
openalex +1 more source
A Systematic Review on Children's Participation in Healthcare From a Child's Perspective
ABSTRACT Background Children have a right to express their opinion on all matters concerning them. For children to be seen as actors in healthcare situations, both the child perspective and the child's perspective are needed. Aim To explore child participation in healthcare from the child's perspective through the following questions: Question 1: What ...
Merja Hietanen +4 more
wiley +1 more source
Urine Peptidomic and Targeted Plasma Protein Analyses in the Diagnosis and Monitoring of Systemic Juvenile Idiopathic Arthritis [PDF]
Xuefeng B. Ling +12 more
openalex +1 more source
Addressing the unmet needs of transitional care in juvenile idiopathic arthritis [PDF]
Nihal Şahin +3 more
openalex +1 more source
Evaluation of cardiovascular risk factors in juvenile idiopathic arthritis [PDF]
Livia BOGONOVSCHI +2 more
openalex +1 more source
Development and initial validation of the parent acceptable symptom state in juvenile idiopathic arthritis (JIA) [PDF]
Giovanni Filocamo +10 more
openalex +1 more source
MTX intolerance in children and adolescents with juvenile idiopathic arthritis [PDF]
Boris Hügle +1 more
openalex +1 more source

