Results 201 to 210 of about 53,788 (241)
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Glucocorticoids in juvenile idiopathic arthritis
Annals of the New York Academy of Sciences, 2014Although the use of corticosteroids in juvenile idiopathic arthritis (JIA) is now much more limited owing to the availability of methotrexate and biological agents, there are clinical scenarios where it is still indicated. For example, corticosteroids may be indicated for intraarticular injections to prevent joint deformities, as a “bridge” drug to ...
MALATTIA, CLARA, MARTINI, ALBERTO
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Adalimumab in juvenile rheumatoid arthritis/juvenile idiopathic arthritis
Expert Review of Clinical Immunology, 2008Chronic arthritis in childhood is the most common pediatric rheumatic disease and can lead to significant short- and long-term disability. TNF-a is a cytokine involved in joint inflammation and destruction. It has been suggested that early and aggressive treatment leads to improved outcomes by ameliorating clinical signs and symptoms, inhibiting joint ...
Katherine Anne B, Marzan +1 more
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Treatment of Juvenile Idiopathic Arthritis
Pediatric Annals, 2012CME Educational Objectives 1. Become familiar with the different types of medications used in treating juvenile idiopathic arthritis (JIA) patients. 2.
Alice Y, Chan, Diana, Milojevic
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Immunosenescence and juvenile idiopathic arthritis
Autoimmunity Reviews, 2012Aging of the immune system (immunosenescence) is characterized by diminished thymus function, decreased output of recent thymic emigrants, compensatory peripheral proliferation of mature T cells and oligoclonal expansions of specific CD28(-) T cells.
Christina, Mayerl, Martina, Prelog
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Imaging of Juvenile Idiopathic Arthritis
Pediatric Radiology, 2006Over the past decade there have been considerable changes in the classification and imaging of juvenile idiopathic arthritis (JIA). Radiology now has a considerable role in the management of JIA, the differential diagnosis, monitoring disease progression and detecting complications. The different imaging modalities available, their role and limitations
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Imaging of Juvenile Idiopathic Arthritis [PDF]
Radiologic Clinics of North America, 2017 Juvenile idiopathic arthritis is an umbrella term covering several distinct categories that share common features. The European League Against Rheumatism and the Pediatric Rheumatology European Society have published a consensus article with recommendations to guide radiologists and clinicians in choosing the best imaging technique for each particular ...
Dimitriou, Christos +5 more
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PROMs for Juvenile Idiopathic Arthritis
2016Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease in children and is an important cause of short-term and long-term disability. The International League of Associations for Rheumatology has defined JIA as arthritis with no apparent cause lasting more than 6 weeks with disease onset prior to age 16.
Consolaro A. +3 more
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Genetics of Juvenile Idiopathic Arthritis
Rheumatic Disease Clinics of North America, 2017Juvenile idiopathic arthritis (JIA) affects approximately 1 in 1000 US children. The cause of JIA is most likely multifactorial and due to an interplay of genetics and environmental factors. This article summarizes the known genetic risk factors for JIA that have been identified, and in some cases replicated, using a variety of methods, including ...
Aimee O, Hersh, Sampath, Prahalad
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Inflammation in Juvenile Idiopathic Arthritis
Pediatric Clinics of North America, 2005Inflammation evolved to aid in the clearance of microorganisms. In pediatric arthritides, the inflammation persists and causes damage to the joint. The contribution of the innate immune system to inflammation is significant and can be exploited therapeutically.
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Outcomes for Juvenile idiopathic arthritis
Paediatrics and Child Health, 2014Abstract Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatological disease of childhood. Despite the current availability of potent disease-modifying anti-rheumatic medications, most children still experience a chronic course with prolonged periods of active disease.
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