Results 51 to 60 of about 86,259 (260)

Whole exome sequencing in a juvenile idiopathic arthritis large family with SERPINA1 gene mutations

open access: yesBMC Rheumatology, 2022
Objectives Although the underlying mechanisms and mediators of arthritis in juvenile idiopathic arthritis are not well understood, accumulated evidence supports the mixt role of genetic and environmental factors.
Cyprian Popescu
doaj   +1 more source

Concealed concern: Fathers' experience of having a child with Juvenile Idiopathic Arthritis [PDF]

open access: yes, 2008
Despite increased research into families of chronically ill children, more needs to be known about the father’s experience. We address this issue through asking: ‘What is it like to be the father of a child with juvenile idiopathic arthritis?’ (JIA ...
A. Madill   +25 more
core   +1 more source

2019 American College of Rheumatology/Arthritis Foundation Guideline for the Treatment of Juvenile Idiopathic Arthritis: Therapeutic Approaches for Non‐Systemic Polyarthritis, Sacroiliitis, and Enthesitis

open access: yesArthritis care & research, 2019
To develop treatment recommendations for children with juvenile idiopathic arthritis manifesting as non‐systemic polyarthritis, sacroiliitis, or enthesitis.
S. Ringold   +25 more
semanticscholar   +1 more source

ASAS definition for sacroiliitis on MRI in SpA : applicable to children? [PDF]

open access: yes, 2017
Background: The Assessment of Spondyloarthritis International Society (ASAS) definition for a'positive' Magnetic Resonance Imaging (MRI) for sacroiliitis is well studied and validated in adults, but studies about the value of this definition in children ...
Baraliakos, Xenofon   +10 more
core   +2 more sources

Progressive pseudorheumatoid dysplasia misdiagnosed as juvenile idiopathic arthritis: a case report

open access: yesJournal of Medical Case Reports, 2021
Background Progressive pseudorheumatoid dysplasia is a rare, autosomal recessively inherited, noninflammatory musculoskeletal disorder caused by mutations occurring in the WNT1-inducible signaling pathway protein 3 gene.
Anjumanara Anver Omar   +4 more
doaj   +1 more source

Histopathology of the gut in rheumatic diseases [PDF]

open access: yes, 2018
The gastrointestinal tract regulates the trafficking of macromolecules between the environment and the host through an epithelial barrier mechanism and is an important part of the immune system controlling the equilibrium between tolerance and immunity ...
Ciccia F.   +4 more
core   +1 more source

Tocilizumab in patients with anti-TNF refractory juvenile idiopathic arthritis-associated uveitis (APTITUDE): a multicentre, single-arm, phase 2 trial

open access: yesThe Lancet Rheumatology, 2020
Summary Background Uveitis associated with juvenile idiopathic arthritis is a cause of major ocular morbidity. A substantial proportion of children are refractory to systemic methotrexate and TNF inhibitors.
A. Ramanan   +9 more
semanticscholar   +1 more source

ProNGF-p75NTR axis plays a proinflammatory role in inflamed joints. A novel pathogenic mechanism in chronic arthritis [PDF]

open access: yes, 2017
To identify the role of mature nerve growth factor (mNGF), its immature form proNGF and their receptors in arthritis ...
Benedetti, Fabrizio De   +9 more
core   +1 more source

Improved Disease Course Associated With Early Initiation of Biologics in Polyarticular Juvenile Idiopathic Arthritis: Trajectory Analysis of a Childhood Arthritis and Rheumatology Research Alliance Consensus Treatment Plans Study

open access: yesArthritis & Rheumatology, 2021
To investigate the effects of early introduction of biologic disease‐modifying antirheumatic drugs (bDMARDs) on the disease course in untreated polyarticular juvenile idiopathic arthritis (JIA).
Mei‐Sing Ong   +499 more
semanticscholar   +1 more source

2019 American College of Rheumatology/Arthritis Foundation Guideline for the Screening, Monitoring, and Treatment of Juvenile Idiopathic Arthritis–Associated Uveitis

open access: yesArthritis & Rheumatology, 2019
To develop recommendations for the screening, monitoring, and treatment of uveitis in children with juvenile idiopathic arthritis (JIA).
S. Angeles-Han   +27 more
semanticscholar   +2 more sources

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